# COM – Oxygen consumption

> COM – Oxygen consumption (iPhone/iPad app by Eduardo Galembeck.)

- Source: https://appshunter.io/ios/app/com-oxygen-consumption/id820289539 (this page in markdown: same URL + `.md`)
- Developer: [Eduardo Galembeck](https://appshunter.io/developer/421224798)
- Category: Education, Medical
- Price: Free
- Age rating: 4+
- Requires: iOS 16.0 · 2 MB
- Languages: English, Portuguese, Spanish
- Released: 2014-02-19
- Data updated: 2026-11-13

## What is COM?

COM simulates experiments with isolated mitochondria in an incubation chamber fitted with an oxygen electrode (oxygraph). Add mitochondria, substrates, ADP, inhibitors and uncouplers one after another and follow, in real time, O₂ consumption and the electrical potential of the inner membrane (Δψ).

The challenge is to find out what each compound does: which ones stimulate oxygen consumption, which ones inhibit it, where each electron transport chain inhibitor acts and how uncouplers separate respiration from ATP synthesis.

• 15 compounds: malate, pyruvate, α-ketoglutarate, succinate, TMPD + ascorbate, ADP + phosphate, rotenone, malonate, antimycin A, cyanide, carbon monoxide, oligomycin, 2,4-dinitrophenol and FCCP
• Recording of dissolved O₂ and Δψ, with a numbered history of every addition
• Several experiments side by side for comparison
• Question guide for undergraduate classes and an answer table for teachers
• Portuguese, English and Spanish

Current version of the COM simulator, created in 1997 at the Educational Technology Laboratory (LTE), Institute of Biology, University of Campinas (Unicamp), and used in biochemistry courses ever since. Part of BIOQUÍMICA +30.

Free, no ads, no sign-up and no data collection. Works offline.

## Is COM safe?

Not enough ratings yet to assess COM.

## Is COM legit?

COM – Oxygen consumption appears to be a legitimate app. The AppsHunter Legitimacy Score for COM is 90 out of 100 points across 7 verification signals from App Store and developer data.


## Version history (last 5 releases)

### 2.0 — 2026-11-12

New version of COM, rebuilt from scratch: oxygraph simulator with 15 compounds, O₂ and Δψ recording, class guide, in Portuguese, English and Spanish. Works offline.

### 1.04 — 2019-01-22

Animations

### 1.03 — 2018-12-14

iOS 11 support

### 1.02 — 2014-05-13

Bug fixes
Videos

### 1.01 — 2014-02-24

The language is auto selected in the beginning of the application.

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## More apps by Eduardo Galembeck

- [Síntese Proteica](https://appshunter.io/ios/app/sintese-proteica/id464324331)
- [Moléculas](https://appshunter.io/ios/app/moleculas/id683443866)
- [The Cell](https://appshunter.io/ios/app/the-cell/id779433459)
- [ARMET](https://appshunter.io/ios/app/armet/id874543777)
- [De la Química Prebiótica a la Bioquímica](https://appshunter.io/ios/app/de-la-quimica-prebiotica-a-la-bioquimica/id885819674)

All apps by Eduardo Galembeck: https://appshunter.io/developer/421224798

## Related topics

[cellular respiration process](https://appshunter.io/ios/topics/cellular-respiration-process)

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*Data collected daily from the US App Store and indexed by [AppsHunter](https://appshunter.io/). User reviews are verbatim App Store reviews. Ratings, prices and chart positions refresh continuously; this snapshot is from 2026-11-13.*
