# CTCAE v4.0 > Standardized system for grading severity of adverse events in medical treatments. (iPhone/iPad app by The Children's Hospital of Philadelphia.) - Source: https://appshunter.io/ios/app/ctcae-v40/id378487242 (this page in markdown: same URL + `.md`) - Developer: [The Children's Hospital of Philadelphia](https://appshunter.io/developer/351401975) - Category: Medical, Reference - Price: Free - Rating: 3.50/5 from 11 App Store ratings · 6 written reviews indexed - Age rating: 12+ - Requires: iOS 9.2 · 3 MB - Languages: American English - Released: 2010-07-09 - Data updated: 2026-06-11 - Monetization: free - User reviews in markdown: https://appshunter.io/ios/app/ctcae-v40/id378487242/reviews.md ## What is CTCAE v4.0? The National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) is a standardized system to quantify or grade the severity of adverse events (AE) that occur with drug treatment or from medical devices. A definition of mild (grade 1), moderate (2), severe (3), life-threatening (4) and death related to AE (5) events is provided for each AE term. The CTCAE v4.02 was published by NCI on October 6, 2009, and is used by many healthcare providers and researchers to characterize adverse events consistently. The Center for Biomedical Informatics (CBMi) at The Children's Hospital of Philadelphia has converted the 190+ pages of the CTCAE v4.02 document into an intuitive iPhone application. With this application, healthcare providers can reference the full CTCAE v4.02 with an iPhone or iPod Touch, allowing for bedside grading at the time of a visit and generally allowing the information to be accessed from anywhere at any time. The application contains all published grading standards for all 26 categories of adverse events as well as event definitions. The application also offers a variety of advantages over the flat file CTCAE v4.02, including: * Hierarchical navigation of adverse event categories * Ability to bookmark adverse events and categories to quickly access frequently graded events * Search for events across names, definitions and grades This application is one example of the many ways in which CBMi helps transform clinical care and research at our institution and across the industry. The Children's Hospital of Philadelphia is a non-profit entity as defined by Section 501(c)(3) of the Internal Revenue Code of 1986. About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking third in National Institutes of Health funding. In addition, its unique family-centered care and public service programs have brought the 460-bed hospital recognition as a leading advocate for children and adolescents. For more information, visit http://www.chop.edu. About The Center for Biomedical Informatics: The Center for Biomedical Informatics (CBMi) resides in The Children's Hospital of Philadelphia Research Institute as the home for development of innovative solutions to healthcare's immediate and long-term informatics needs. We provide informatics-focused services, products, and educational programs to Children's Hospital clinicians and researchers and seek to transform their craft with high-impact, low-cost solutions. For more information, visit http://www.research.chop.edu/cbmi. References: Please note that NCI has directed us to use the May 29, 2009 reference without regard to updates. Our app uses the most updated version of the CTCAE despite our reference to the original. National Cancer Institute Common Terminology Criteria for Adverse Events v4.0 NCI, NIH, DHHS. May 29, 2009 NIH publication # 09-7473 ## Key features - Standardized adverse event grading system - Definitions for event severity (grades 1-5) - Hierarchical navigation of categories - Bookmark frequently used events - Search across names, definitions, and grades ## Recent user reviews (6 of 6) All indexed reviews: https://appshunter.io/ios/app/ctcae-v40/id378487242/reviews.md ### 3/5 — Update for ios11 *2017-10-02, version 1.2* Needs to be updated for iOS 11...also adding terms to my favorites doesn’t work. ### 1/5 — App is not working for iOS 11 *2017-09-26, version 1.1* App is not working ### 3/5 — Please update!!! *2017-04-26, version 1.1* Please update this app! I use it so frequently but my iPhone informs me that this app won't work with the next iOS update (I have version 10.something currently.) I don't want to be left high and dry!! I'd also like to be able to use the bookmarks but they have never worked on my phone. Pretty glitchy. Please update!!!! ### 3/5 — Useful But Needs Updating *2016-11-24, version 1.1* However a couple of suggestions- should b able to alphabetize Bookmarks & should open with the Search/Alpha list page, rather than Bookmark. Added 11/2016: definitely needs updating, many glitches, some functions freeze the app ### 2/5 — Needs to be updated for iOS 9 *2015-10-26, version 1.1* Decent interface but at $1.99(USD) this app is a little pricey. It also needs to be updated for iOS 9, interface is a little glitchy. Would also like to see MedDRA and lay term mapping, like a synonym list or something. ### 5/5 — Thank you :) *2012-08-01, version 1.1* Very very useful and easy to use. ## Frequently asked questions about CTCAE v4.0 ### What is CTCAE v4.0 used for? CTCAE v4.0 is a standardized system used by healthcare providers and researchers to quantify or grade the severity of adverse events that occur with drug treatment or from medical devices. It provides definitions for mild (grade 1) through death related to adverse events (grade 5). ### What information does CTCAE v4.0 provide? The application contains all published grading standards for over 26 categories of adverse events, along with event definitions. It allows users to reference the full CTCAE v4.02 document for bedside grading and information access. ### How does CTCAE v4.0 help users? It offers hierarchical navigation of adverse event categories, the ability to bookmark frequently accessed events and categories, and a search function to find events by name, definition, or grade. This makes referencing the CTCAE v4.02 document more intuitive than a flat file. ### Is CTCAE v4.0 available on multiple devices? Based on the information provided, CTCAE v4.0 is designed for iPhone and iPod Touch devices. It was released on July 9, 2010, and its latest version is 1.2, last updated on September 29, 2017. ### What is the age rating for CTCAE v4.0? CTCAE v4.0 has an age rating of 12+. This indicates it is suitable for users aged 12 and older. ### Does CTCAE v4.0 have ads? No, CTCAE v4.0 does not contain advertisements. The application is free to download and use without any ad interruptions. ### How often is CTCAE v4.0 updated? The application was last updated on September 29, 2017, with version 1.2. While the initial release was in 2010, the last update indicates it has received some maintenance or feature additions. ### What is the user rating for CTCAE v4.0? CTCAE v4.0 has a rating of 3.5 stars from 11 ratings. This suggests a mixed but generally positive reception from its user base. ## Version history (last 3 releases) ### 1.2 — 2017-09-29 This app has been updated by Apple to display the Apple Watch app icon. Support for iOS 11 ### 1.1 — 2010-08-30 - Updated terminology, grades and definitions to the CTCAE 4.03 revision (6/14/2010) - Changed the term "Categories" to the canonical term of "System Organ Class" as defined by the NCI ### 1.0 — 2010-07-09 No release notes. ## Apps similar to CTCAE v4.0 | App | Rating | Price | Category | | --- | --- | --- | --- | | [Pharmatheque Plus](https://appshunter.io/ios/app/pharmatheque-plus/id1568085280) | — | Free | Medical | | [HemeOncBuddy](https://appshunter.io/ios/app/hemeoncbuddy/id1579207336) | 5.0 (17) | Free | Medical | | [CTCAE 6 GO](https://appshunter.io/ios/app/ctcae-6-go/id6749604539) | 5.0 (3) | Free | Medical | | [ASCO Guidelines](https://appshunter.io/ios/app/asco-guidelines/id1238827183) | 4.8 (195) | Free | Medical | | [Med Scanner - Pharmacology](https://appshunter.io/ios/app/med-scanner-pharmacology/id1629604400) | 4.8 (22) | Free | Medical | | [ESMO Interactive Guidelines](https://appshunter.io/ios/app/esmo-interactive-guidelines/id1037353712) | 4.8 (139) | Free | Medical | ## More apps by The Children's Hospital of Philadelphia - [Vaccines on the Go](https://appshunter.io/ios/app/vaccines-on-the-go/id692759940) - [Proband - Pedigrees Made Simple](https://appshunter.io/ios/app/proband-pedigrees-made-simple/id829791227) - [MyCHOP](https://appshunter.io/ios/app/mychop/id1261956406) - [ADAPTS](https://appshunter.io/ios/app/adapts/id1493575447) - [iManageSCD](https://appshunter.io/ios/app/imanagescd/id1503238507) All apps by The Children's Hospital of Philadelphia: https://appshunter.io/developer/351401975 ## Related topics [ctagemedy](https://appshunter.io/ios/topics/ctagemedy) · [ctcae](https://appshunter.io/ios/topics/ctcae) · [v40](https://appshunter.io/ios/topics/v40) · [ctcae 5 pro](https://appshunter.io/ios/topics/ctcae-5-pro) · [nihfcu](https://appshunter.io/ios/topics/nihfcu) · [adverse](https://appshunter.io/ios/topics/adverse) --- *Data collected daily from the US App Store and indexed by [AppsHunter](https://appshunter.io/). User reviews are verbatim App Store reviews. Ratings, prices and chart positions refresh continuously; this snapshot is from 2026-06-11.*