# IOTA ADNEX

> Ovarian tumor risk assessment tool for medical professionals. (iPhone/iPad app by Katholieke Universiteit te Leuven.)

- Source: https://appshunter.io/ios/app/iota-adnex/id925286040 (this page in markdown: same URL + `.md`)
- Developer: [Katholieke Universiteit te Leuven](https://appshunter.io/developer/925286039)
- Category: Medical
- Price: $19.99
- Rating: 5.00/5 from 1 App Store ratings
- Age rating: 4+
- Requires: iOS 8.0 · 4 MB
- Languages: American English
- Released: 2014-10-28
- Data updated: 2026-06-25
- Monetization: paid
- User reviews in markdown: https://appshunter.io/ios/app/iota-adnex/id925286040/reviews.md

## What is IOTA ADNEX?

The ADNEX risk model can be used by medical doctors to preoperatively estimate the likelihood that an ovarian (including para-ovarian and tubal) tumor is benign, borderline, a stage I cancer, stage II-IV cancer, or secondary metastatic cancer (i.e. metastasis of non-adnexal cancer to the ovary). The model is based on data derived from women found to have at least one adnexal tumor that was judged not to be physiological, underwent a standardized ultrasound examination, and was later selected for surgery. 

The ADNEX model contains nine predictors: age, serum CA-125 (U/ml), type of center (oncology vs other), maximum lesion diameter, proportion of solid tissue, number of papillary projections, the presence of >10 cyst locules, acoustic shadows, and ascites. An oncology center is defined as a tertiary referral center with a specific gynecological oncological unit. 

The model was developed by clinicians and statisticians from the International Ovarian Tumour Analysis (IOTA) group, and is based on clinical and ultrasound data from almost 6000 women recruited at 24 centers in 10 countries (Italy, Belgium, Sweden, Czech Republic, Poland, France, UK, China, Spain, and Canada).

A full description of model development and validation is given in Van Calster B, Van Hoorde K, Valentin L, Testa AC, Fischerova D, Van Holsbeke C, Savelli L, Franchi D, Epstein E, Kaijser J, Van Belle V, Czekierdowski A, Guerriero S, Fruscio R, Lanzani C, Scala F, Bourne T, Timmerman D. Evaluating the risk of ovarian cancer before surgery using the ADNEX model to differentiate between benign, borderline, early and advanced stage invasive, and secondary metastatic tumours: prospective multicentre diagnostic study. The BMJ 2014;349:g5920.

## Key features

- Preoperative risk estimation for ovarian tumors
- Differentiates between benign, borderline, and cancerous tumors
- Utilizes nine clinical and ultrasound predictors
- Based on extensive international research data
- Developed by leading clinicians and statisticians


## Frequently asked questions about IOTA ADNEX

### What is IOTA ADNEX used for?

IOTA ADNEX is a medical application designed for doctors to estimate the preoperative risk of ovarian tumors being benign, borderline, or cancerous. It helps differentiate between various stages of malignancy and secondary metastatic cancers.

### What are the predictors used by IOTA ADNEX?

The model incorporates nine predictors: patient's age, serum CA-125 levels, type of medical center, maximum lesion diameter, proportion of solid tissue, number of papillary projections, presence of over 10 cyst locules, acoustic shadows, and ascites.

### How was the IOTA ADNEX model developed?

The model was developed by clinicians and statisticians from the International Ovarian Tumour Analysis (IOTA) group. It is based on clinical and ultrasound data from nearly 6000 women across 24 centers in 10 countries.

### What is the price of IOTA ADNEX?

IOTA ADNEX is a paid application, with a price of $19.99. This one-time purchase grants access to the full functionality of the risk assessment tool.

### On which devices can IOTA ADNEX be used?

IOTA ADNEX is available for use on iPhones, iPads, and iPods. It is designed to be compatible with Apple's mobile operating system.

### How frequently is IOTA ADNEX updated?

The latest version of IOTA ADNEX is 1.0.5, which was last updated on May 10, 2017. Users can expect the core functionality to remain stable, though major updates may be infrequent.

### What is the age rating for IOTA ADNEX?

IOTA ADNEX has an age rating of 4+. This indicates that the content is generally suitable for all ages, though it is intended for medical professionals.

### Does IOTA ADNEX contain advertisements?

The provided data does not specify whether IOTA ADNEX contains advertisements. As a paid medical application, it is generally expected to be ad-free.

## Version history (last 3 releases)

### 1.0.5 — 2017-05-10

This app has been updated by Apple to display the Apple Watch app icon.

Code optimization and minor enhancements

### 1.0.1 — 2014-11-05

Some minor fixes.

### 1.0.0 — 2014-10-27

No release notes.

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*Data collected daily from the US App Store and indexed by [AppsHunter](https://appshunter.io/). User reviews are verbatim App Store reviews. Ratings, prices and chart positions refresh continuously; this snapshot is from 2026-06-25.*