# Liposome Calculator

> Calculates liposome solution components, concentrations, and analysis parameters. (iPhone/iPad app by Roman Volinsky.)

- Source: https://appshunter.io/ios/app/liposome-calculator/id988429323 (this page in markdown: same URL + `.md`)
- Developer: [Roman Volinsky](https://appshunter.io/developer/977951850)
- Category: Education, Utilities
- Price: $3.99 (on sale, was $4.99)
- Rating: 5.00/5 from 1 App Store ratings · 1 written reviews indexed
- Age rating: 4+
- Requires: iOS 17.0 · 2 MB
- Languages: American English
- Released: 2015-05-05
- Data updated: 2026-08-20
- Monetization: paid
- User reviews in markdown: https://appshunter.io/ios/app/liposome-calculator/id988429323/reviews.md

## What is Liposome Calculator?

Liposome Calculator helps in preparation of liposome solutions. Components concentrations (molarity and mg/ml) and moles, and volumes of stock solutions are calculated based upon data provided, such as: initial concentrations of the stock solutions, and required molar ratios. 
Application is comprised of two activities: First is Calculator, that helps to parameterize and prepare the complex suspension systems. Second is Analyzer that helps in analysis of liposome parameters, such as number of molecules per vesicle, inner, entrapped volume and encapsulation.  
 
The Calculator follows the common liposome preparation procedure (volard.wordpress.com):
        
1. Stock solutions of lipids (or any other compound) are mixed in appropriate molar ratios.
2.Obtained mixture is purged with nitrogen and organic solvent is finally evacuated under vacuum.
3.Obtained lipid mixture is hydrated and extruded or sonicated, according to the needs.
 
Calculator features:
 
Unlimited number of components is available. Additional components are added by touching “Solution# (+)” field and deleted by touching the “Molar% (-)” field. 
 
Application is fully interactive: all system parameters are updated immediately after any input from user (if it is sufficient!). For example: final molar concentration and molar ratios of the components can be adjusted at any time if molar concentrations of starting solutions and final suspension volume are provided. Upon any of the aforementioned changes, the application will calculate the volumes of the initial solutions to fit the desired parameters. 

The database is used to store compounds data, that will be available to autocomplete upon typing compounds' names in the main calculator.
  
Important points.
 
The user should follow the simple rule to ensure proper functionality: all known data should be provided in the following order (Only yellow fields are adjustable): solution or solute nicknames(optional)-> Mw (if needed)-> initial concentrations (must!)-> volumes (if known)-> molar ratios (if known)-> Total Molarity (if known)-> Total Volume (if known).
 
Sum of stock solution volumes doesn't have to be equal to final suspension volume (Refer to the procedure)!
 
Watch out the molar ratios to ensure that all starting components are included! Program will expel components for which insufficient data is provided! Thus, for example concentration in g/l cannot be included in calculations if Mw of solute is not provided.
 

Liposome Analysis Activity Layout:

The activity window divided to data panel (left) and results panel (right).
 
The data panel parameters:
 
Total Concentration: Total lipid concentration. Automatically uploaded from Liposome Calculator activity and can be corrected at any time.
Total Volume: Total solution volume. Automatically uploaded from Liposome Calculator activity and can be corrected at any time.
Diameter: Average liposome outer diameter in nanometers (one billionth of meter).
Bilayer Thickness: Lipid bilayer thickness in angstroms.
Molecular Area: Single lipid molecule area in square angstroms.
 
 
The results panel parameters:
 
Number of Molecules: Average number of lipid molecules in a single liposome (vesicle).
Number of Liposomes: Average total number of liposomes in the analyzed solution.
Inner Volume: Average volume entrapped in a single liposome.
Surface Area: Average surface area of a single liposome.
Encapsulation Efficiency: In this context is represented by ratio of the total entrapped volume to total solution volume. Look up for the definition in regards to the drug encapsulation.
 
Important Points.
 
Usage of high total concentrations (particularly in molar range) leads to an inappropriate system analysis (encapsulation efficiency values exceeding 100%), since physical state of system cannot anymore be considered as a dilute vesicle suspension.

## Key features

- Calculate component concentrations (molarity, mg/ml)
- Calculate moles and stock solution volumes
- Parameterize complex suspension systems
- Analyze liposome parameters (molecule count, volume, encapsulation)
- Unlimited components
- Interactive system updates
- Compound database for autocompletion

## Recent user reviews (1 of 1)

All indexed reviews: https://appshunter.io/ios/app/liposome-calculator/id988429323/reviews.md

### 5/5 — Good one!

*2018-05-29*

quite unique and working

## Frequently asked questions about Liposome Calculator

### What is Liposome Calculator used for?

Liposome Calculator is used to prepare liposome solutions by calculating component concentrations, moles, and stock solution volumes. It also aids in analyzing liposome parameters such as molecule count per vesicle and encapsulation efficiency.

### How does Liposome Calculator handle component concentrations?

The calculator allows for unlimited components and interactively updates system parameters, including final molar concentration and molar ratios, immediately after user input. It calculates the volumes of initial solutions needed to meet desired parameters.

### What liposome analysis features does Liposome Calculator offer?

The analyzer activity helps in determining the number of molecules per vesicle, inner and entrapped volume, and encapsulation efficiency. These parameters are crucial for understanding liposome characteristics.

### Is Liposome Calculator available on multiple devices?

Yes, Liposome Calculator is supported on both iPhone and iPad devices, making it accessible for users on Apple's mobile platforms.

### What is the price of Liposome Calculator?

Liposome Calculator is a paid application, priced at $3.99. This one-time purchase grants access to all its features for liposome preparation and analysis.

### How often is Liposome Calculator updated?

The application was last updated on October 6, 2024, indicating ongoing support and potential improvements. The latest version is 6.0.

### What is the age rating for Liposome Calculator?

Liposome Calculator has an age rating of 4+, making it suitable for a wide range of users, including students and professionals in relevant scientific fields.

### Does Liposome Calculator have ads?

No, Liposome Calculator does not contain advertisements. As a paid application, it provides an ad-free experience for users focused on scientific calculations.

## Version history (last 5 releases)

### 6.0 — 2024-10-06

Compatibility update.

### 5.9 — 2023-08-10

Compatibility update.

### 5.8 — 2022-05-16

Compatibility update.

### 5.7 — 2022-01-20

Compatibility update.

### 5.6 — 2021-07-18

Compatibility update.

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## More apps by Roman Volinsky

- [Acid Base pH](https://appshunter.io/ios/app/acid-base-ph/id977951851)
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All apps by Roman Volinsky: https://appshunter.io/developer/977951850

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*Data collected daily from the US App Store and indexed by [AppsHunter](https://appshunter.io/). User reviews are verbatim App Store reviews. Ratings, prices and chart positions refresh continuously; this snapshot is from 2026-08-20.*