# NEXO: Clinical Reasoning — One clinical case a day

> Daily clinical case simulator for medical professionals and students. (iPhone/iPad app by Thiago Longo Moraes.)

- Source: https://appshunter.io/ios/app/nexo-clinical-reasoning/id6761273295 (this page in markdown: same URL + `.md`)
- Developer: [Thiago Longo Moraes](https://appshunter.io/developer/1888570229)
- Category: Medical, Education
- Price: Free with in-app purchases
- Rating: 4.00/5 from 1 App Store ratings · 2 written reviews indexed
- Age rating: 17+
- Requires: iOS 15.1 · 43 MB
- Languages: American English, French (France), German (Germany), Brazilian Portuguese, Russian, European Spanish
- Released: 2026-06-07
- Data updated: 2026-11-09
- Monetization: freemium
- User reviews in markdown: https://appshunter.io/ios/app/nexo-clinical-reasoning/id6761273295/reviews.md

## What is NEXO?

A new clinical case every day. The same case for everyone, with a global ranking. Clues open one by one and you decide when to lock in the diagnosis. Free, forever.

Made for students, professionals, and specialists.

Portuguese, English, Spanish, French, German, and Russian. Switch anytime.

HOW IT WORKS
Each case has six clues, released in sequence: chief complaint, history, physical exam, additional workup, imaging or lab findings, and final finding.

Submit your hypothesis whenever you want by typing the diagnosis name or the ICD-10/11 code.

The earlier you get it right, the more synapses and XP you earn.
Missed? The next clue opens. You get up to six attempts.
At the end, the case explanation walks through the diagnostic reasoning.

EACH GUESS GUIDES THE NEXT
The color of each guess shows how close you got. On the ICD-10 map, the branches you ruled out dim and the branch with the answer lights up when a guess gets close.

GAME MODES
Daily Case
A new case every day, free forever. Everyone plays the same case and competes in the same global ranking.

Adrenaline
One case a day against the clock. Choose the dose before you start: the higher it is, the less time you get and the bigger the reward.

Continents
Regional tracks with the epidemiology of each region. Unlock with synapses, on any plan.

Multimedia
Cases with X-ray, CT, ECG, ultrasound, pathology, electrophoresis, and many other exams. Unlock with synapses, on any plan.

Archive
Missed a day? Past daily cases stay in the Archive, ready to play on Pro and Max.

PROGRESS

Stats
Find out at which clue you usually reach the correct diagnosis and in which specialties you get the most answers right. Your stats by clue and by specialty show your strengths and gaps, with no guessing.

Groups, University, and Global Ranking
Compete in the global ranking. Choose your university in your Profile and play for it in the Universities ranking. Create a private group with your friends, or join with an invite code, and follow the group ranking.

Achievements
Achievements are organized into tracks. Each milestone in the game unlocks a badge, and you can see what you have already completed and the next step in each track.

PLANS
Plans unlock access to the Archive, include the explanation of each case at no cost, and show the case area and the ICD range from the first clue.

Subscribing does not buy right answers. It buys repetition.

SUBSCRIPTIONS
NEXO Pro and NEXO Max are auto-renewable subscriptions processed by Apple. Payment is charged to your App Store account at confirmation of purchase. The subscription automatically renews unless canceled at least 24 hours before the end of the current period. Renewal is charged within 24 hours prior to the end of the period. You can manage your subscription and turn off auto-renewal in App Store Settings after purchase. Any unused portion of a free trial period is forfeited when purchasing a paid subscription. The price and duration of each plan are displayed on the purchase screen in the app.

EDUCATIONAL USE
NEXO is a medical study tool and is not Software as a Medical Device (SaMD). It does not issue diagnoses, does not replace patient history, physical examination, or clinical management, and is not intended for clinical care of real patients. All content is strictly educational.

Privacy Policy: https://nexo.wiki.br/privacy
Terms of Use: https://nexo.wiki.br/terms

## Key features

- Daily clinical cases
- Global and group rankings
- Clue-based diagnosis progression
- Multiple game modes (Daily Case, Adrenaline, Continents, Multimedia)
- Performance statistics and tracking
- Achievements and badges
- Multilingual support

## Pricing and in-app purchases

Base price: Free.

**Subscriptions**

| Subscription | Price | Period |
| --- | --- | --- |
| Pro Monthly | $4.99 | per month |
| Pro Annual | $29.99 | per year |
| Max Annual | $99.99 | per year |
| Max Monthly | $14.99 | per month |

**One-time purchases**

| Purchase | Price | Type |
| --- | --- | --- |
| 100 Sinapses | $0.99 | one-time |
| 350 Sinapses | $2.99 | one-time |
| 1500 Sinapses | $9.99 | one-time |
| 750 Sinapses | $4.99 | one-time |


## Is NEXO safe?

Not enough ratings yet to assess NEXO.

## Is NEXO legit?

NEXO: Clinical Reasoning has limited verification signals. The AppsHunter Legitimacy Score for NEXO is 58 out of 100 points across 7 verification signals from App Store and developer data.

## Recent user reviews (2 of 2)

All indexed reviews: https://appshunter.io/ios/app/nexo-clinical-reasoning/id6761273295/reviews.md

### 4/5 — Excellent diagnostic game with room to grow

*2026-09-22*

I rarely write app reviews, but I’ve really enjoyed NEXO and have played over 200 cases. I’m a fourth-year medical student in the U.S., and I’ve found the diagnostic format and ICD-10 system genuinely fun and useful for practicing clinical reasoning. I especially enjoy trying to make the diagnosis with as little information as possible.

My biggest limitation right now is the amount of content available at the different subscription levels. I would subscribe to Pro in a heartbeat if it gave access to a larger library of practice cases. During my trial, I completed the 30 additional cases in about two days, so a monthly limit doesn’t provide much value for someone who wants to use NEXO regularly for practice. More access to previous cases, or a larger/unlimited practice library, would make a subscription much more appealing to me.

I’d also love an option to hide the early ICD range on paid plans. Having the ICD range immediately available narrowed my differential enough that cases became noticeably easier. For advanced learners, an optional “Expert Mode” where the ICD range is hidden or only revealed when requested would be fantastic.

I also think the leaderboard could eventually benefit from separating competitive ranking from subscription XP multipliers. A score based on accuracy, case difficulty, and number of clues used would make ranking feel more representative of diagnostic performance while still allowing subscribers to receive XP bonuses for progression.

Finally, some of the social features still seem to be developing. I received a challenge from another player, but tapping the notification didn’t take me anywhere, and I couldn’t find a way to access it afterward.

Overall, I really like what the developers are building. The core diagnostic game is excellent, and I’m leaving this feedback because I’d genuinely like to subscribe and continue using NEXO long-term as the case library and features grow.

### 5/5 — Melhor jogo médico!!

*2026-08-27*

Excelente jogo! Eu tinha dificuldade em treinar casos clínicos, esse aplicativo resolveu 100% dos meus problemas. Na minha última prova fui tri bem porque lembrei de um caso que eu joguei na semana anterior e era parecido com o conteúdo da prova. Simplesmente, FENOMENAL 10/10

## Frequently asked questions about NEXO

### What is NEXO: Clinical Reasoning?

NEXO: Clinical Reasoning is a medical education app that presents users with a new clinical case each day. It allows users to progress through clues, make diagnoses, and compete on a global leaderboard.

### Is NEXO: Clinical Reasoning free to use?

The core 'Daily Case' mode of NEXO: Clinical Reasoning is free forever. However, certain features like accessing the Archive, explanations, and case area details require a subscription to NEXO Pro or NEXO Max.

### What are the subscription options for NEXO: Clinical Reasoning?

NEXO offers Pro and Max subscription plans, available monthly or annually. The Pro Annual plan includes a 7-day free trial. Subscriptions unlock access to past cases and detailed case explanations.

### How does the scoring and ranking work in NEXO: Clinical Reasoning?

Users earn synapses and XP based on how early they correctly identify the diagnosis. The app features a global ranking, university-specific rankings, and private group rankings for competitive play.

### What languages does NEXO: Clinical Reasoning support?

NEXO: Clinical Reasoning supports multiple languages, including Portuguese, English, Spanish, French, German, and Russian. Users can switch between these languages at any time within the app.

### What is the age rating for NEXO: Clinical Reasoning?

NEXO: Clinical Reasoning has an age rating of 17+, indicating it is suitable for mature users. This is likely due to the complex medical scenarios presented.

### How often is NEXO: Clinical Reasoning updated?

The app was last updated on November 6, 2026, with version 1.0.2. This suggests a recent update, and users can expect ongoing maintenance and potential new features.

### Does NEXO: Clinical Reasoning have ads?

No, NEXO: Clinical Reasoning does not contain advertisements. The app is free to use for its daily cases and offers optional subscriptions for enhanced features.

## Version history (last 3 releases)

### 1.0.2 — 2026-11-06

NEXO is now native on iPad. Plus Adrenaline mode, achievements organized into tracks, and a new result screen.

New
- NEXO on iPad: a native app with a two-column layout, a sidebar you can collapse in landscape, and a screen that adapts when you rotate or resize it.
- Adrenaline mode: a case against the clock. Choose the dose before you play; the higher the dose, the less time you get and the bigger the reward.
- Achievement tracks, so you can see what you have already completed and what the next step is.
- Universities: pick yours in your Profile, compete in the Universities tab inside Ranking, and complete the achievement tracks for representing it.
- ICD-10 map in the game: the branches your guesses ruled out are dimmed, and the branch that holds the answer lights up when a guess lands in the same chapter, group, or category, or when the ICD range is revealed.
- Flashcard button on the result screen: it copies a ready-made search, and pasting that into Anki lists the cards you already have for the diagnosis. Once the explanation is unlocked, it also copies the diagnosis with the pathophysiology and the treatment, ready for a new card.
- A new result screen, with your accuracy for the case and sharing as a vertical or square image.

Improved
- Game Modes screen with a preview of the Archive of daily cases, Continents, and Multimedia.
- The daily case and the countdown follow your time zone and turn over at midnight where you are.
- Before you spend synapses, the app shows the cost in a window of its own and asks you to confirm.
- The Social tab is gone. Friends moved to your Profile, groups became the Group tab in Ranking, and Achievements now have a tab of their own.
- A new floating navigation bar.
- In Continents and Multimedia, the card of a case you already played opens straight to the result. In the Archive, this works on Pro and Max.
- A single field for the referral code and the coupon: the app recognizes which of the two you entered.

Keep NEXO up to date.

### 1.0.1 — 2026-08-31

ICD-10 chapters inside the game, a streak that survives a wrong answer, and a button to report any case straight from the result screen.

New
- ICD-10 chapters in the game: tap the book to see all 22 code ranges and, once the code hint unlocks, the chapter of the current case.
- Report a problem with this case: flag a clue, the diagnosis, the explanation, the media, or the translation from the result screen.
- Skip clue, at the cost of one attempt.
- NEXO avatars in your profile.
- Streak calendar and a breakdown of correct answers by clue in your stats.
- Referrals: for every 3 friends you invite who finish their first case, you earn 1,000 sinapses and 7 days of Pro.

Improved
- The diagnosis field follows the keyboard, and the latest clue stays visible while you type.
- More accurate diagnosis search in all 6 languages.
- Streak protection now also covers a wrong answer on the daily case, and the streak keeps growing with a correct training case the same day.
- Daily Reward is collected when you open the app, without interrupting you.
- The result screen shows the case number and date.

Fixed
- Search that stopped responding after a guess.
- XP bars at the level milestone.
- "Next case" from the Archive returning to the list.

### 1.0 — 2026-06-07

No release notes.

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*Data collected daily from the US App Store and indexed by [AppsHunter](https://appshunter.io/). User reviews are verbatim App Store reviews. Ratings, prices and chart positions refresh continuously; this snapshot is from 2026-11-09.*