# Spearhead Calculator — Research purpose calculator

> Research purpose calculator (iPhone/iPad app by Matthias Unterhuber.)

- Source: https://appshunter.io/ios/app/spearhead-calculator/id6754850104 (this page in markdown: same URL + `.md`)
- Developer: [Matthias Unterhuber](https://appshunter.io/developer/1850504452)
- Category: Medical, Utilities
- Price: Free
- Age rating: 4+
- Requires: iOS 18.2 · 1 MB
- Languages: English
- Released: 2025-11-12
- Data updated: 2026-09-23
- User reviews in markdown: https://appshunter.io/ios/app/spearhead-calculator/id6754850104/reviews.md

## What is Spearhead Calculator?

SPEARHEAD is a research tool designed to explore and predict individual response to spironolactone therapy in patients with heart failure with preserved ejection fraction (HFpEF). Built on a gradient-boosting (XGBoost) model, it provides individualized estimates of treatment effect for research and validation purposes. It is powered by the model presented in the following study:  10.1016/j.ebiom.2023.104795.

Disclaimer
This application is intended solely for research and scientific validation purposes.
It does not provide medical diagnosis or treatment recommendations.
Users must not rely on the results for clinical decisions and should always seek professional medical advice before making any medical or therapeutic decision.


## Version history (last 2 releases)

### 1.1 — 2026-09-21

- Updated to iOS version 26+ compatibility
- Resolved some SSL bugs which led to connection timeout

### 1.0 — 2025-11-13

No release notes.

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*Data collected daily from the US App Store and indexed by [AppsHunter](https://appshunter.io/). User reviews are verbatim App Store reviews. Ratings, prices and chart positions refresh continuously; this snapshot is from 2026-09-23.*