# STEM Defense — Build, Defend, Evolve&Mutate

> Build, Defend, Evolve&Mutate (iPhone/iPad app by Andrea Carlomaria Sertorio.)

- Source: https://appshunter.io/ios/app/stem-defense/id6502572873 (this page in markdown: same URL + `.md`)
- Developer: [Andrea Carlomaria Sertorio](https://appshunter.io/developer/1465623599)
- Category: Games, Medical, Puzzle, Strategy
- Price: $6.99
- Age rating: 9+
- Requires: iOS 15.0 · 411 MB
- Languages: American English
- Released: 2024-05-24
- Data updated: 2026-08-22
- User reviews in markdown: https://appshunter.io/ios/app/stem-defense/id6502572873/reviews.md

## What is STEM Defense?

About This Game

"STEM Defense" immerses yourself in a strategic battle within the human body, where you manipulate pathways and tower placements on a dynamic hexagonal grid. This educational tower defense game teaches players about the immune system through engaging gameplay, focusing on the defense against microscopic invaders.

Key Features

Path Expansion: Dynamically extend the pathways pathogens travel to strategically shape each level and increase the effectiveness of your defenses.

Tower Placement Strategy: Strategic placement of your towers is essential. Elevate your towers to gain damage bonuses, crucial for optimizing defense effectiveness.

Mutation-Based Upgrades: Enhance your defenses through epigenetic modifications, providing temporary boosts, and genetic mutations for permanent enhancements. This mirrors real-life biological defense mechanisms.

Experience and Genetic Enhancements: Gain experience to unlock advanced defensive capabilities and permanent genetic upgrades, enhancing your ability to combat pathogens.

Varied Enemy Types: Encounter diverse pathogens, each with unique abilities. Develop strategies to handle enemies that can regenerate, accelerate, or spawn additional threats.

Endless Replayability: With a multitude of genetic enhancements and adaptive enemy tactics, each game offers new challenges and decisions, ensuring unique experiences with every playthrough.

Coming Soon:Acquired immunity mechanics!!

Support Independent Development

As a solo developer not well-versed in the art of social media, I rely on the support of players like you. If you've enjoyed "STEM Defense," please help spread the word and make it known to others!


## Version history (last 5 releases)

### 1.0.6 — 2026-08-17

Two years of work, in one update.

PLAY IN YOUR OWN LANGUAGE
STEM Defense now speaks 31 languages, from Arabic and Japanese to Russian and Portuguese. Menus, cards, tooltips and the whole upgrade page are translated — over a thousand lines each, not just the buttons.

A SAVE FILE YOU CAN TRUST
Resetting your progress now really resets it, and the reset survives closing the game. Creative mode no longer touches your records or your experience: try anything you like, your real progress stays your own.

FAIRER FIGHTS
The boss no longer takes a life twice for the same hit. A wave no longer breaks when a spawn point is missing. Victory is checked before the cards appear, so the end screen is never buried under them.

SMALLER THINGS, FELT EVERY GAME
The camera stays still in the main menu. Upgrade prerequisites read correctly. Currency is counted once, not twice. Losing with enemies still on the field ends the run cleanly instead of leaving it half-finished.

Thank you for playing, and for waiting.

### 1.0.5 — 2024-06-07

BIg Bugs FIxed

### 1.0.3 — 2024-06-04

Bug fixed

### 1.0.2 — 2024-05-31

Guide & Immunology, minor fixes

### 1.0.1 — 2024-05-27

Ortographic Camera movement

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| --- | --- | --- | --- |
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## More apps by Andrea Carlomaria Sertorio

- [Flux : AR Adventure](https://appshunter.io/ios/app/flux-ar-adventure/id1465623600)
- [AR Anatomy ++](https://appshunter.io/ios/app/ar-anatomy-plus-plus/id1493567338)
- [Blood Crush](https://appshunter.io/ios/app/blood-crush/id1536344832)

All apps by Andrea Carlomaria Sertorio: https://appshunter.io/developer/1465623599

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*Data collected daily from the US App Store and indexed by [AppsHunter](https://appshunter.io/). User reviews are verbatim App Store reviews. Ratings, prices and chart positions refresh continuously; this snapshot is from 2026-08-22.*