# TRT Plus — For TRT & Enhanced Athletes > TRT and enhanced athlete protocol and biomarker tracking app. (iPhone/iPad app by Nathan Southern.) - Source: https://appshunter.io/ios/app/trt-plus/id6448075516 (this page in markdown: same URL + `.md`) - Developer: [Nathan Southern](https://appshunter.io/developer/1683426811) - Category: Health & Fitness - Price: Free (on sale, was $12.99) - Rating: 4.10/5 from 12 App Store ratings · 18 written reviews indexed - Age rating: 12+ - Requires: iOS 15.1 · 51 MB - Languages: American English - Released: 2023-05-01 - Data updated: 2026-08-24 - Monetization: paid - User reviews in markdown: https://appshunter.io/ios/app/trt-plus/id6448075516/reviews.md ## What is TRT Plus? Hormone optimization. Understood. The framework for TRT and enhanced protocols. At a glance: a protocol planner built to replace your spreadsheets and notes. Under the hood: a full hormone optimization platform with AI-powered bloodwork analysis, advanced pharmacokinetic modeling, and a knowledge base covering everything from TRT fundamentals to peptides and advanced enhanced protocols. See the full framework at trtplus.app NOT A LOGGING APP. A COMPLETE FRAMEWORK. From ordering the right bloodwork through TRT Plus pathology partners, to interpreting your results, dialing in with the Testimator™, and adjusting your protocol — every feature exists to close that loop. Order → Interpret → Dial In → Adjust → Repeat. MY PROTOCOL — Daily Dashboard: your full schedule at a glance — checkboxes, visual syringe, injection stacking — 80+ pre-configured compounds: anabolics, TRT ancillaries, peptides, GLPs, SARMs — one tap to add — Dose Titration: set automatic ramping and tapering plans for any compound — Peptide reconstitution calculator — enter dry powder, bac water calculates automatically — Pharmacokinetic charting: the only TRT app with a true multi-route PK model — injectables, orals, peptides, and testosterone cream — Peak-to-trough T level fluctuation modeling based on your exact protocol — see the swing, not just the average — Frequency Tuning: detects when your peak-to-trough swing is higher than it needs to be and suggests the most practical schedule to smooth it — Rotation Planner: set your sites once, the app forecasts the sequence — Testosterone cream with Topi-CLICK® interface and site-specific absorption modeling — Inventory management with advance reorder notifications — Classic mode for straightforward TRT. Advanced mode for the full enhanced stack. MY BLOODWORK — Automated OCR scanning — upload any photo or screenshot, markers extract automatically — Enhanced reference ranges calibrated for TRT and enhanced athletes, not the general population — Reference ranges that move with your health — the Cardio-Metabolic Cascade feeds your cardiovascular markers into a personalized testosterone ceiling — Hormonal balance scored against your true androgenic load using exclusive DHT receptor potency and paracrine amplification model — Biomarker Score: a weighted composite across 15 markers — hormones, cardiovascular, liver, kidney, hematology — Free T via four methods: Vermeulen, Mazer, Södergård, and Zakharov — exclusive to TRT Plus, and the only model accurate at supra-physiological levels — AI Bloodwork Report: 8 sections interpreting your results alongside your active protocol in context — Pathology partner integration for athlete-specific panels: ApoB, Cystatin C, GGT (region dependent) THE TESTIMATOR™ Predict your testosterone response across any protocol before you run it — anchored to your actual bloodwork, not a population average. Understand the shape of your response. KNOWLEDGE BASE 100+ topics across 15 categories. 150+ studies cited. Zero generic AI content. Every biomarker and recommendation covered with the depth for someone actually running a protocol. THE BUILD Built by an application engineer with 25 years of experience — and on TRT — in collaboration with TRT clinics, coaches, and pathology partners. Grounded in de-identified data from thousands of real-world TRT patient results. Not a general health app retrofitted. Built from the ground up for this population. Charted #2 in App Store Health & Fitness · Top Paid TRT App Full feature breakdown, screenshots, and the engine behind it all: trtplus.app ## Key features - Protocol dashboard - Compound plotter charts - Bloodwork analysis - Medication reminders - Injection rotation planning - Inventory tracking - Pharmacokinetic modeling ## Recent user reviews (10 of 18) All indexed reviews: https://appshunter.io/ios/app/trt-plus/id6448075516/reviews.md ### 5/5 — Great for „TRT“ *2026-07-09* The app is fantastic and incredibly intuitive to use! The daily reminder helps you remember all your compounds and the Tritration function makes planning your cycle a breeze. There are so many compounds available. -The support is also really good! ### 5/5 — ⭐️⭐️⭐️⭐️⭐️⭐️⭐️⭐️ *2026-07-06* Excellent support and a fantastic app👍🏽👍🏽👍🏽 ### 5/5 — Fantastic app *2026-04-23* I had this on android and moved to iPhone and installed again, app works so much smoother on iPhone, great app with amazing functions. Developer gives the best support and help anyone could ask for and sets the bar for other developers ### 1/5 — Not into it *2026-03-19* Not what I was expecting all, very unintuitive. I will be asking for a refund **Developer response:** Thanks for the feedback. TRT Plus bridges clinical-grade features and consumer usability, which is genuinely one of the hardest design challenges in health apps, the advanced concepts clinics work with aren't always intuitive without that medical context. If you haven't already, there's a Classic/Advanced toggle in the top right of the My Protocol screen that simplifies the view significantly... worth trying before you go. I understand the app isn't for everyone, Apple Health and basic medication trackers are always an option for simpler needs. ### 2/5 — Very unintuitive *2026-03-03* Heh, really wanted to like this app, but it is not user friendly as it does not follow any usual guidelines about buttons and icons. I still cannot find how to delete one of peptides: In most cases when I hit peptide name the keyboard pops up and hides the input :), so I spend time trying to figure out how to hide the keyboard, on tapping almost anywhere else... nothing happens. How to log and find previous data is also jumps through the hoops. Try to change the frequency. .. you will hit date picker 20 times and will be close to break your phone :). What to do with the rotation widget is still a mystery for me: I simply cannot find how to specify and how to find the previous value :) **Developer response:** Hi McPooh123, thanks for the detailed feedback. Happy to walk you through a few things that might help. To delete a compound, tap the trash icon. After typing, tap the tick on the keyboard to dismiss it. Every field has built-in guidance, just tap any heading with a chevron > next to it. For the rotation schedule, tap Rotation > and a detailed guide will pop up with simple instructions to follow. For Rotation setup specifically you just enter your preferred sites, for example Left Delt, Right Delt, Left Ventroglute, Right Ventroglute... and the app forecasts them out on the calendar rotating evenly. So you don't have to remember where you injected last or log it, the app just tells you what site is next. This section also features an extensive knowledge base covering injection methods, site comparisons, IM vs SubQ and more. I'd also recommend switching to Classic mode if you haven't already. It's now the default for all new installs and simplifies the experience significantly. To switch, tap the layers icon top right of the My Protocol screen. The frequency picker was touchy on some devices and has been resolved in V2.6, released yesterday. Please update and let me know if you can get to frequency in less than 20 taps, and without wanting to break your phone. Hopefully that clears things up. Would love for you to give the app another chance and revise the rating if the experience is more intuitive in classic mode. ### 5/5 — App is broken *2025-12-23* It’s good app but after last update it’s not showing me anything anymore. Cheers **Developer response:** The latest release required that you re enter your protocol, as there was a major update. If you just setup your T and compound amounts again, it should all be fine. support@trtplus.app ### 5/5 — Mr white *2025-11-05* I found this updated version very helpful and the online support from Nathan has been extremely useful **Developer response:** Really appreciate the kind words, glad the support has been helpful! Always happy to assist. ### 5/5 — Really useful *2025-09-03* I find the app incredibly useful for those who may be managing their own TRT. The most useful aspect is the analyst of bloodwork and AI which I find invaluable. Definitely worth the cost. **Developer response:** Really appreciate the kind words. The bloodwork analysis is where the majority of the app's development effort has gone, so it's great to hear it's landing well. Most guys stick to the My Protocol section and never discover it, so you're definitely getting the most out of the app. Thanks for the support! ### 5/5 — Best app for TRT *2025-04-29* I can’t recommend This app enough, I work away from home and travel a lot for work, I have a busy lifestyle, the app helps me keep track of everything, and the ai report is really handy, the developer of the app is always happy to help and responds promptly, it almost like have a coach or a doctor in your pocket **Developer response:** Thank you, really appreciate it. TRT is an incredible game changer, but without something keeping you on track, it can quickly become a hassle to manage, especially with a busy schedule. That's exactly what the app was built for. Love the 'coach in your pocket'... that's the goal right there. ### 5/5 — Keeps getting better *2025-03-24* I’ve had this app for awhile now. I must say the updates keep making this app better. It’s helping me keep track of my protocol. **Developer response:** Really appreciate the loyalty, thank you. Guys like yourself are a big part of what drives the updates, plenty more still to come. If there's anything you'd like to see added, always happy to hear it. ## Frequently asked questions about TRT Plus ### What is TRT Plus? TRT Plus is a specialized application designed for individuals undergoing Testosterone Replacement Therapy (TRT) and enhanced athletes. It provides tools for detailed protocol management, bloodwork analysis, and health optimization. ### What kind of data does TRT Plus analyze? TRT Plus analyzes various health data, including bloodwork markers relevant to TRT and performance. It offers enhanced reference ranges tailored for optimization and can interpret key markers like testosterone, estradiol, and IGF-1. ### Can TRT Plus help with medication management? Yes, TRT Plus includes automated medication reminders to ensure you take your supplements and TRT-related compounds on time. It also features an inventory management system to track your supplies and reorder needs. ### Does TRT Plus support international bloodwork units? Yes, TRT Plus supports international bloodwork units for common markers such as Testosterone, Estradiol, Free T, DHT, HbA1c, ApoB, and IGF-1, allowing for easy conversion and analysis. ### How does TRT Plus help with injection planning? TRT Plus offers an injection rotation planner to help you maintain an even rotation between injection sites. It also features a visual syringe to show today's injections and allows for quick injection stacking. ### What is the pricing for TRT Plus? TRT Plus is available for a one-time purchase of $12.99. This grants you access to all its features for managing your TRT and athletic performance. ### On which devices can I use TRT Plus? TRT Plus is available for iPhone, iPad, and iPod. It is designed to be compatible with Apple's mobile operating systems. ### How often is TRT Plus updated? The latest version of TRT Plus is 2.5, and it was last updated on March 17, 2026. This indicates a commitment to ongoing development and feature enhancements. ## Version history (last 5 releases) ### 2.9 — 2026-08-09 • Frequency Tuning - Detects when your peak-to-trough swing is higher than it needs to be and shows you how to smooth it. Adjusting how often you dose is often the quickest route to fewer peak-driven side effects — elevated hematocrit, and excess conversion to estrogen and DHT. Ester and cream aware: your PTF% is calculated for your exact dose, frequency and testosterone formulation, and the recommendation is the most practical schedule to meaningfully flatten the curve — set it in one tap. • Discuss with your AI - Your bloodwork report can now continue the conversation. Tap Discuss with your AI to hand off the full analysis straight into ChatGPT, Gemini or Grok. It travels with a detailed prompt to provide context on the TRT Plus engine and methodology. Your assistant can answer real follow-up questions. • Pharma GLP-1s, GH & hCG - Verified brands can now be added. Tap Pharmaceutical product to search by product name — Ozempic, Wegovy, Mounjaro, Genotropin, Norditropin, Humatrope, Pregnyl, Novarel, Ovidrel, and more. The concentration is filled in from the manufacturer's regulatory label. Community requested. • Compound Database Updates - Minoxidil added to TRT Ancillaries, Accutane added to Advanced. Community requested. • GH-Equivalent Index - Your IGF-1 now translates into an estimated daily Growth Hormone output expressed in IU. The model maps your reading along an IGF-1-to-GH response curve calibrated against published dose-response data and saturating response (Ghigo et al. 1999, Janssen et al. 1997). It's a common currency: see how much headroom your own production leaves for added GH, read what a peptide like CJC/Ipamorelin is buying you, or check how an exogenous GH dose compares to what your IGF-1 actually converts to. • Free T Method Advisor - The My Free T calculator now reads your Total T and SHBG and recommends the estimation method best matched to your bloodwork. The common models each hold up only within the range they were built for: Vermeulen in the normal physiological range, Södergård as a high-end estimate, Zakharov where SHBG saturates at supraphysiologic testosterone. When your levels sit outside where your current method is reliable, you'll be prompted to switch to the one that actually fits your profile. Upgrade methods in one tap for a more accurate Free T. • Bloodwork Tiers - "Optimal" was doing too much. Your bloodwork now scores against four tiers, so each marker says what it means. Optimal — lower or controlled is better. TRT Calibrated — the dialed-in range for someone on TRT, above standard ranges by design. Enhanced — supraphysiologic, a performance choice rather than a health optimum. Tolerated — carries some intrinsic risk, accepted and monitored because surrounding markers are low-risk. ### 2.8 — 2026-07-06 • Dose Titration - Ramping and tapering plans can now be set for any compound. Define a target, timeframe, and adjustment frequency — the app builds a dated week-by-week plan and automatically adjusts on schedule. Re-open the plan at any time to see completed, current, and upcoming steps. Community requested. • Today Progress Bar - A live dose tracker showing how many compounds have been taken and how many remain, with a progress bar that fills as you go. • Engine Schematic - The My Biomarkers knowledge base now includes a visual map of the full scoring engine, showing how each biomarker feeds into and relates to the others across the cardiovascular, hormonal, and metabolic systems. • Compound Detail Strip - A live inventory countdown shows days remaining with color-coded urgency, and active Ramping or Tapering plans are summarized at a glance at the bottom of each compound card. • Nebido Support - Testosterone Undecanoate is now fully supported. Long-interval dosing from Every 3 to Every 16 Weeks is available exclusively when Nebido is selected. The fluctuation chart and Testimator both use a calibrated depot absorption model — levels rise to peak at day 7 post-injection and the Testimator timeline expands to 14 weeks to give a meaningful view of the full dosing cycle. A 5 mL syringe is set to hold the 4 mL standard volume. Community requested. • Titration Forecasting - Dose titration schedules are now visible on compound charts, showing your planned ramping or tapering steps, target achievement date, and elimination timeline in one integrated view. • HDL & LDL Markers - LDL Cholesterol replaces HDL as the secondary cardiovascular marker, displayed automatically when superior marker ApoB is not present in your bloodwork. • Compound Database Updates - Dutasteride added to Advanced, BPC + TB-500 and CJC + Ipamorelin blend entries added to Peptides. Community requested. ### 2.7 — 2026-05-08 • Testosterone Cream - Topical testosterone is now fully supported in My Protocol, represented as a Topi-CLICK® dispenser with +/- click buttons to adjust. • Peptide Reconstitution Calculator - When adding a peptide, you're guided through setting concentration. Enter your vial's dry powder amount and bac water volume calculates automatically. You can override in any direction — adjust bac water to recalculate concentration, or enter a target concentration to recalculate water volume. Unusual concentrations are flagged. • The Testimator - Significant redesign to simplify data input. Baseline Protocol is now pulled from your Testosterone details in My Protocol, Total Testosterone anchors the model from My Biomarkers, and Blood Test Timing has been added to reflect whether blood was drawn at peak or trough. • My Bloodwork - A dedicated hub to order the TRT Plus panel, upload results, generate your AI report, and book a consult. Each step is clearly labelled to guide you through the full bloodwork cycle. • High / Low Indicators - Each biomarker card now shows an H or L when a result falls outside TRT Plus optimised reference ranges. • Transdermal Pharmacokinetic Models - Cream compounds use two dedicated models for transdermal delivery. Absorbed amount is calculated via a Michaelis-Menten saturation model using site-specific parameters. The Compound Plotter and PTF calculation use a Bateman bi-exponential function, producing an accurate rise-to-peak curve rather than the instantaneous depot model used for injectables. • Testosterone Cream & Injectable Equivalent Converter - Select a weekly amount and application site to see your injectable equivalent in mg/W, using a Michaelis-Menten model with site-specific absorption ceilings and half-saturation points. • Protocol Validation - Ensures your compounds and amounts in My Protocol reflect what you were actually taking at the time of bloodwork, before being sent to AI for interpretation. • Chart Aesthetic Update - Charts and score gauges refined to match the glassmorphic feel of the app. Onboarding hints added. • Order Bloodwork - Choose between Essential and Comprehensive panels, order via our pathology partners, or use the combined marker list for private ordering or to show your doctor. • Compound Slots - My Protocol now supports up to 10 compounds, doubled from 5. • Injection Frequency Science - The Frequency knowledge base now includes a clinical breakdown of why injection interval matters. Steady-state accumulation theory and peak-to-trough data compare protocols from fortnightly to daily. Four cited studies are linked, including Nankin 1987 and the 2025 Walia clinical review. • E2 & DHT: The Paracrine Picture - New knowledge base section on E2 and DHT. Both are produced locally inside cells — a paracrine process — which is why plasma levels tell only part of the story, and why AIs and 5ARIs act systemically rather than at the symptom site. • GH Secretagogues & IGF-1 Bloodwork Timing - Three new sections covering how GH secretagogues work, the liver's 4–8 hour GH-to-IGF-1 conversion window, and a compound-by-compound bloodwork timing guide. • HDL & eGFR Markers - HDL Cholesterol and eGFR are reintroduced as secondary cardiovascular and kidney markers, shown automatically when ApoB or Cystatin C are not detected in your bloodwork. • Cardio-Metabolic Cascade - The formula behind your personalised testosterone reference range is now documented, showing how your cardiovascular and metabolic markers cascade into your scoring thresholds. ### 2.6 — 2026-04-03 • Personalized Testosterone Reference Range - In the context of TRT, setting a testosterone reference range based on the general slopulation misses the point entirely. Total T now scores against your own cardiovascular and haematological profile, with your personal biomarker health determining how much range you've earned. • Hematocrit Scoring Engine Upgrade - Hematocrit now uses a dynamic threshold system driven by six cascading cardiovascular markers: Blood Pressure, ApoB, CRP, Body Fat, and HbA1c. When all six are green, the optimal Hct ceiling extends, recognising that a lean, cardiovascularly healthy individual carries materially lower risk at higher Hct than standard population thresholds imply. • E2 Scoring Engine Upgrade - Estradiol scoring now uses the same DHT-adjusted Androgenic Load as the A:E gauge. When DHT is provided, both systems now evaluate E2 balance against the full androgenic picture. • A:E Ratio Rescue Logic - A healthy A:E ratio can now override an elevated absolute E2 value in the amber zone. If your androgenic load is sufficient to keep the ratio in the balanced range, E2 will reflect that context rather than penalising a higher absolute number in isolation. • A:E Gauge Zone Labels - The A:E and T:E ratio gauge now displays five clinically meaningful zone labels: Estrogenic, E2 Leaning, Balanced, E2 Low, and Androgenic. Amber states reflect directional imbalance, giving clearer context to where your ratio sits and what it means. • E2 Modal Overhaul - Comprehensive restructure of the Estradiol info modal for improved readability. Enhanced reference range updated. New content covers gynecomastia risk factors including DHT's inhibitory role, protocol peak-to-trough imbalance, and the 5–6 month hormonal adaptation window before considering an AI. AI reference points added for enhanced and high T protocols. • Unified Card Aesthetic - App cards redesigned with dark gradient surface, top-edge shimmer highlight, and shadow elevation. • Improved Tappable Area - The Frequency picker now has a more reliable hit target. ### 2.5 — 2026-03-17 • Classic & Advanced Mode - Switch between views using the layers icon in My Protocol. Classic mode shows your core TRT inputs. Advanced mode unlocks compound stacking, pharmacokinetic plotters, inventory management, and your full daily schedule. Your data is never affected. • A:E Ratio - Total Androgenic Load - When DHT is entered in your biomarkers, the T:E ratio upgrades to an A:E (Androgenic Load:Estrogen) ratio for a more complete picture of hormonal balance. A:E incorporates DHT's greater androgen receptor binding affinity and longer receptor residence time versus testosterone, using an asymmetric additive model that captures both suppressed DHT states and the non-linear paracrine amplification of elevated DHT at the tissue level. Full methodology, formula, and citations are in the My Biomarkers info modal (Russell & Wilson, 1994; Langley et al., 1995). • Medication Reminder Quick Actions - Long press or expand any notification to snooze for 15 or 30 minutes, or tap Mark as Taken to log your protocol without opening the app. • Smartwatch Support - Quick actions are now available on Apple Watch and compatible Android smartwatches (Wear OS, Galaxy Watch, Garmin). Mark as taken or snooze from your wrist. • Info Modals Redesigned - Cleaner horizontal layout across the app replaces the previous stacked design, giving more vertical space for content. Tappable headings now feature a guillemet suffix for improved discoverability. • Compound Database Updates - Glow Stack, Klow Stack, and NAD+ added to Peptides. • AI Bloodwork Report Enhancements - Tightened report structure with a new composite Anabolic Potential Rating, plus two new sections: Cardiovascular Risk Profile (Clogging Quartet framework) and Healthspan Assessment. Growth Hormone analysis now adapts to your active protocol. • App Icon & Splash Screen Redesign - New liquid glass-style icon and splash screen designed for iOS 26 and modern Android aesthetics. • Liquid Glass Tab Navigator - Bottom tab bar redesigned with a liquid glass treatment consistent with the new icon aesthetic. • Display Layout Optimisation - Full layout refactor for consistent experience across all tablet devices and larger mobile form factors. • Blood Test Scanning Enhancements - OCR now reliably detects DHT across a wider range of lab report formats, including Androstanolone, 5a-DHT, and related naming conventions. • Free T Import - A new Import button in My Free T pulls Total T and SHBG values directly from My Biomarkers, eliminating manual entry. • Testimator Import & Export - Import your Baseline Protocol from My Protocol and My Biomarkers directly into The Testimator. Export your Target Protocol back to My Protocol. • Timezone-Aware Scheduling - Your injection and medication schedule automatically stays in sync when you travel or change timezone. • Enhanced Navigation - Tapping a medication reminder notification navigates directly to the relevant compound. Tapping a compound in the daily dashboard scrolls to and opens its widget details. • Syringe Preference Saved - Your selected syringe is now remembered across app launches. • Peak & Trough Toast Notifications - A toast notification confirms when the peak or trough flag is updated against a blood test entry in My Biomarkers. • Injection Guide - Updated knowledge base covering TRT protocol evolution, a Deep IM / Shallow IM / SubQ comparison table, and site-specific techniques for ventroglute, deltoid, lat, glute, and quad, cited studies (Gunes et al. 2013, Nakajima et al. 2020, Figueiredo et al. 2022). ## Apps similar to TRT Plus | App | Rating | Price | Category | | --- | --- | --- | --- | | [Box Breathing - Float](https://appshunter.io/ios/app/box-breathing-float/id1605558336) | 4.8 (318) | Free | Health & Fitness | | [SleepHQ](https://appshunter.io/ios/app/sleephq/id6451459781) | 4.7 (553) | Free | Health & Fitness | | [Setgraph: Gym Workout Tracker](https://appshunter.io/ios/app/setgraph-gym-workout-tracker/id1209781676) | 4.7 (5,987) | Free | Health & Fitness | | [Evolt Active](https://appshunter.io/ios/app/evolt-active/id1464632516) | 1.9 (93) | Free | Health & Fitness | | [Spren Body Composition Scanner](https://appshunter.io/ios/app/spren-body-composition-scanner/id1664503999) | 4.7 (1,486) | Free | Health & Fitness | | [Stronglifts 5x5 Workout Plan](https://appshunter.io/ios/app/stronglifts-5x5-workout-plan/id488580022) | 4.9 (76,516) | Free | Health & Fitness | ## Related topics [testosterone calculator pro](https://appshunter.io/ios/topics/testosterone-calculator-pro) · [anabolic](https://appshunter.io/ios/topics/anabolic) · [trt tabii](https://appshunter.io/ios/topics/trt-tabii) --- *Data collected daily from the US App Store and indexed by [AppsHunter](https://appshunter.io/). User reviews are verbatim App Store reviews. Ratings, prices and chart positions refresh continuously; this snapshot is from 2026-08-24.*