# Clinical Practice Guidelines vs CDC Yellow Book

The clearest difference is review sentiment: Clinical Practice Guidelines at 67% against CDC Yellow Book's 20%. Clinical Practice Guidelines also leads on rating (4.8 vs 4.2) and in-app purchases (none vs 2). On price, ads and device support there is nothing between them.

Both are free to download. CDC Yellow Book sells 1 one-off in-app purchase. Clinical Practice Guidelines asks for nothing beyond the download.

Clinical Practice Guidelines holds the better App Store score, 4.8 against 4.2. That said, the two scores are not equally well evidenced: Clinical Practice Guidelines has 531 ratings behind it against 69, so its average is the more settled of the two. Written reviews point the same way: 67% of Clinical Practice Guidelines's written reviews are positive against 20% of CDC Yellow Book's.

Clinical Practice Guidelines ships an update every 6 months, CDC Yellow Book every 17 months. Both last shipped on October 29, 2026.

## The numbers

| Metric | Clinical Practice Guidelines | CDC Yellow Book |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[4.8 (531 ratings)](https://appshunter.io/ios/app/clinical-practice-guidelines/id1079272170/reviews)** | [4.2 (69 ratings)](https://appshunter.io/ios/app/cdc-yellow-book/id1235766820/reviews) |
| Number of ratings | **531** | 69 |
| Positive reviews | **66.7% of reviews** | 20.0% of reviews |
| In-app purchases | **No** | Yes |
| Ads | No | No |
| Update frequency | **Every 6 months** | Every 17 months |
| Monetization | **Free** | Free with in-app purchases |
| Size | 113 MB | 10 MB |
| Requires iOS | **12.0** | 15.0 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 12+ | 17+ |
| Developer | [The Endocrine Society](https://appshunter.io/developer/438308415) | [Unbound Medicine, Inc.](https://appshunter.io/developer/300420400) |

## What reviewers say

### Clinical Practice Guidelines

[App page](https://appshunter.io/ios/app/clinical-practice-guidelines/id1079272170)

Access endocrine society clinical practice guidelines directly on your device. Utilize interactive tools like risk calculators and diagnostic algorithms. Save important information, take notes, and share resources with colleagues.

**Highlights:** Point-of-care guideline access, Interactive risk calculators, Diagnosis and treatment algorithms, Medication charts, Bookmark and note-taking, Shareable PDFs

**Features:** macOS Compatibility

**In-app purchases:** none


### CDC Yellow Book

[App page](https://appshunter.io/ios/app/cdc-yellow-book/id1235766820)

Access the U.S. government's most current travel health guidelines, including vaccine recommendations and destination-specific advice. This app offers comprehensive information for staying healthy abroad, with features like search, notes, and favorites.

**Highlights:** Pre-travel vaccinations and preventative care, Destination-specific guidelines, Advice for travelers with specific health needs, Full text search, Custom notes and highlights, Reference maps, tables, and charts

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| CDC Yellow Book | $29.99 | one-time |


## Frequently asked questions

### Is Clinical Practice Guidelines free?

Clinical Practice Guidelines is free to download, with no in-app purchases.

### Is CDC Yellow Book free?

CDC Yellow Book is free to download, with in-app purchases available.

### Which has better reviews, Clinical Practice Guidelines or CDC Yellow Book?

Clinical Practice Guidelines is rated higher. Clinical Practice Guidelines averages 4.8 out of 5 from 531 ratings, while CDC Yellow Book averages 4.2 from 69 ratings.

### Do Clinical Practice Guidelines or CDC Yellow Book have ads?

Neither Clinical Practice Guidelines nor CDC Yellow Book shows ads.

### Which is updated more often, Clinical Practice Guidelines or CDC Yellow Book?

Clinical Practice Guidelines ships an update every 6 months, and CDC Yellow Book every 17 months. Most recently, Clinical Practice Guidelines was updated on October 29, 2026 and CDC Yellow Book on October 29, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*