# Clinical Practice Guidelines vs SemaCalc

The clearest difference is price: Clinical Practice Guidelines at Free against SemaCalc's $3.99. Clinical Practice Guidelines also leads on rating (4.8 vs 4.2) and ratings volume (448 vs 6). SemaCalc's advantage is chart position (#199 vs unranked). On review sentiment, update cadence, ads and in-app purchases there is nothing between them.

Clinical Practice Guidelines is free to download; SemaCalc costs $3.99 up front. Neither carries in-app purchases, so what you see is what you pay.

Clinical Practice Guidelines holds the better App Store score, 4.8 against 4.2. That said, the two scores are not equally well evidenced: Clinical Practice Guidelines has 448 ratings behind it against 6, so its average is the more settled of the two. Written reviews complicate that: 67% of Clinical Practice Guidelines's written reviews are positive against 71% of SemaCalc's, so the app with the better star average is not the one people write more warmly about.

Clinical Practice Guidelines ships an update every 6 months, SemaCalc every 4 months. The most recent releases landed on October 14, 2026 and September 30, 2026 respectively.

## The numbers

| Metric | Clinical Practice Guidelines | SemaCalc |
| --- | --- | --- |
| Price | **Free** | $3.99 |
| Rating | **[4.8 (448 ratings)](https://appshunter.io/ios/app/clinical-practice-guidelines/id1079272170/reviews)** | [4.2 (6 ratings)](https://appshunter.io/ios/app/semacalc/id6502772237/reviews) |
| Number of ratings | **448** | 6 |
| Positive reviews | 66.7% of reviews | **71.4% of reviews** |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | Every 6 months | **Every 4 months** |
| Monetization | **Free** | Paid |
| Best chart rank | — | **#199** |
| Size | 113 MB | 16 MB |
| Requires iOS | **12.0** | 15.1 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 12+ | 17+ |
| Developer | [The Endocrine Society](https://appshunter.io/developer/438308415) | [Cynthia Ruiz](https://appshunter.io/developer/1746738074) |

## What reviewers say

### Clinical Practice Guidelines

[App page](https://appshunter.io/ios/app/clinical-practice-guidelines/id1079272170)

Access endocrine society clinical practice guidelines directly on your device. Utilize interactive tools like risk calculators and diagnostic algorithms. Save important information, take notes, and share resources with colleagues.

**Highlights:** Point-of-care guideline access, Interactive risk calculators, Diagnosis and treatment algorithms, Medication charts, Bookmark and note-taking, Shareable PDFs

**Features:** macOS Compatibility

**In-app purchases:** none


### SemaCalc

[App page](https://appshunter.io/ios/app/semacalc/id6502772237)

**Currently charting:** #199 Top Paid · Medical (US App Store)

This medical app simplifies semaglutide dilution calculations for healthcare professionals. It provides precise dilution guidance and recommends appropriate syringes for dosage preparation, enhancing accuracy and efficiency.

**Highlights:** Semaglutide dilution calculation, Precise dilution guidance, Syringe recommendations, Dosage preparation, Workflow streamlining

**Features:** macOS Compatibility

**In-app purchases:** none


## Frequently asked questions

### Is Clinical Practice Guidelines free?

Clinical Practice Guidelines is free to download, with no in-app purchases.

### Is SemaCalc free?

SemaCalc costs $3.99, with no in-app purchases.

### Which has better reviews, Clinical Practice Guidelines or SemaCalc?

Clinical Practice Guidelines is rated higher. Clinical Practice Guidelines averages 4.8 out of 5 from 448 ratings, while SemaCalc averages 4.2 from 6 ratings.

### Do Clinical Practice Guidelines or SemaCalc have ads?

Neither Clinical Practice Guidelines nor SemaCalc shows ads.

### Which is updated more often, Clinical Practice Guidelines or SemaCalc?

Clinical Practice Guidelines ships an update every 6 months, and SemaCalc every 4 months. Most recently, Clinical Practice Guidelines was updated on October 14, 2026 and SemaCalc on September 30, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*