# Medissima vs SYNAPSE I СИНАПС

The clearest difference is in-app purchases: Medissima at none against SYNAPSE I СИНАПС's 3. Medissima also leads on update cadence (weekly vs monthly) and iOS requirement (8.0 vs 15.0). SYNAPSE I СИНАПС's advantage is review sentiment (100% vs 92%). On price, ads and device support there is nothing between them.

Both are free to download. SYNAPSE I СИНАПС sells 3 in-app purchases, starting at $12.99 per month. Medissima asks for nothing beyond the download.

Medissima ships an update weekly, SYNAPSE I СИНАПС monthly. The most recent releases landed on October 6, 2026 and October 19, 2026 respectively.

## The numbers

| Metric | Medissima | SYNAPSE I СИНАПС |
| --- | --- | --- |
| Price | Free | Free |
| Positive reviews | 91.7% of reviews | **100.0% of reviews** |
| In-app purchases | **No** | Yes |
| Ads | No | No |
| Update frequency | **Weekly** | Monthly |
| Monetization | **Free** | Free with in-app purchases |
| Size | 52 MB | 24 MB |
| Requires iOS | **8.0** | 15.0 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [Artur Lisyukov](https://appshunter.io/developer/1082147746) | [Dmitry Tereshin](https://appshunter.io/developer/1774693004) |

## What reviewers say

### Medissima

[App page](https://appshunter.io/ios/app/medissima/id1082147747)

A unique mobile game designed for medical professionals, featuring medical riddles that encrypt human disease names. It offers 10 difficulty levels and hand-drawn imagery to test and expand clinical knowledge.

**Highlights:** Medical riddles for disease names, 10 difficulty levels, Hand-drawn illustrations, Learn clinical medicine, Share on VKontakte

**Features:** macOS Compatibility

**In-app purchases:** none


### SYNAPSE I СИНАПС

[App page](https://appshunter.io/ios/app/synapse-i/id6737121601)

This app provides a comprehensive medical knowledge base with articles, clinical case studies, and video courses for healthcare professionals. It offers tools like calculators and scales to aid in clinical practice and learning.

**Highlights:** Extensive medical article database, Interactive clinical case studies, Video courses from experts, Clinical calculators and scales, Preparation for international exams, Medical English learning

**Features:** macOS Compatibility

**In-app purchases (3)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Подписка на 1 месяц | $12.99 | per month |
| Подписка на 3 месяца | $34.99 | per 3 months |
| Подписка на 12 месяцев | $129.99 | per year |


## Frequently asked questions

### Is Medissima free?

Medissima is free to download, with no in-app purchases.

### Is SYNAPSE I СИНАПС free?

SYNAPSE I СИНАПС is free to download, with in-app purchases available.

### Do Medissima or SYNAPSE I СИНАПС have ads?

Neither Medissima nor SYNAPSE I СИНАПС shows ads.

### Which is updated more often, Medissima or SYNAPSE I СИНАПС?

Medissima ships an update weekly, and SYNAPSE I СИНАПС monthly. Most recently, Medissima was updated on October 6, 2026 and SYNAPSE I СИНАПС on October 19, 2026.

---

*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*