# Biochemistry Mastery vs USMLE

The clearest difference is ratings volume: USMLE at 5K against Biochemistry Mastery's 37. Biochemistry Mastery's advantage is iOS requirement (9.0 vs 15.0). On price, rating, review sentiment and update cadence there is nothing between them.

Both are free to download. Biochemistry Mastery sells 1 one-off in-app purchase and USMLE sells 1 in-app purchase, starting at $49.99 per month. Whichever you choose, the download price is not the number that matters.

On the App Store both sit at effectively the same score — 4.6 for Biochemistry Mastery against 4.7 for USMLE. That said, the two scores are not equally well evidenced: USMLE has 5K ratings behind it against 37, so its average is the more settled of the two. Written reviews are what separate them: 50% of Biochemistry Mastery's written reviews are positive against 49% of USMLE's.

Biochemistry Mastery ships an update monthly, USMLE every 6 weeks. Both last shipped on November 2, 2026.

## The numbers

| Metric | Biochemistry Mastery | USMLE |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [4.6 (37 ratings)](https://appshunter.io/ios/app/biochemistry-mastery/id1102548368/reviews) | **[4.7 (5K ratings)](https://appshunter.io/ios/app/usmle-rx/id1222119266/reviews)** |
| Number of ratings | 37 | **5K** |
| Positive reviews | **50.0% of reviews** | 48.9% of reviews |
| In-app purchases | Yes | Yes |
| Ads | No | No |
| Update frequency | **Monthly** | Every 6 weeks |
| Monetization | Free with in-app purchases | Free with in-app purchases |
| Size | 64 MB | 40 MB |
| Requires iOS | **9.0** | 15.0 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 12+ | 17+ |
| Developer | [gWhiz, LLC](https://appshunter.io/developer/286531712) | [MedIQ Learning, LLC](https://appshunter.io/developer/344457828) |

## What reviewers say

### Biochemistry Mastery

[App page](https://appshunter.io/ios/app/biochemistry-mastery/id1102548368)

Master biochemistry with over 400 practice questions, flashcards, and study strategies. Study offline anytime, anywhere, and track your progress. Upgrade for full access to all content and explanations.

**Highlights:** 400+ practice questions, 100+ terminology flashcards, Study strategies, Biochemistry mnemonics, Offline access, Progress tracking

**Features:** macOS Compatibility

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| One time purchase to unlock all content (NOT a subscription). | Free | one-time |


### USMLE

[App page](https://appshunter.io/ios/app/usmle-rx/id1222119266)

Master medical school and the USMLE with a comprehensive resource app. Access board-style questions, interactive learning modules, flashcards, and videos. Study anytime, anywhere with cloud syncing and personalized study tools.

**Highlights:** Thousands of USMLE board-style questions, Nearly 800 eLearning modules, Over 14,000 flashcards, Over 80 hours of high-yield videos, Cloud syncing across devices, Spaced repetition study tool

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| RX360+ | $49.99 | per month |


## Frequently asked questions

### Is Biochemistry Mastery free?

Biochemistry Mastery is free to download, with in-app purchases available.

### Is USMLE free?

USMLE is free to download, with in-app purchases available.

### Which has better reviews, Biochemistry Mastery or USMLE?

USMLE is rated higher. Biochemistry Mastery averages 4.6 out of 5 from 37 ratings, while USMLE averages 4.7 from 5K ratings.

### Do Biochemistry Mastery or USMLE have ads?

Neither Biochemistry Mastery nor USMLE shows ads.

### Which is updated more often, Biochemistry Mastery or USMLE?

Biochemistry Mastery ships an update monthly, and USMLE every 6 weeks. Most recently, Biochemistry Mastery was updated on November 2, 2026 and USMLE on November 2, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*