# Manual MSD versión pro vs Vademecum Internacional

The clearest difference is review sentiment: Manual MSD versión pro at 94% against Vademecum Internacional's 20%. Manual MSD versión pro also leads on rating (4.9 vs 4.0) and in-app purchases (none vs 4). Vademecum Internacional's advantage is update cadence (every 2 months vs every 5 months). On price, ads and device support there is nothing between them.

Both are free to download. Vademecum Internacional sells 4 in-app purchases, starting at $0.99 per month. Manual MSD versión pro asks for nothing beyond the download.

Manual MSD versión pro holds the better App Store score, 4.9 against 4.0. Both are backed by a comparable volume of ratings — 141 and 33 respectively. Written reviews point the same way: 94% of Manual MSD versión pro's written reviews are positive against 20% of Vademecum Internacional's.

Manual MSD versión pro ships an update every 5 months, Vademecum Internacional every 2 months. Both last shipped on November 2, 2026.

## The numbers

| Metric | Manual MSD versión pro | Vademecum Internacional |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[4.9 (141 ratings)](https://appshunter.io/ios/app/manual-msd-version-pro/id1151854781/reviews)** | [4.0 (33 ratings)](https://appshunter.io/ios/app/vademecum-internacional/id1449022938/reviews) |
| Number of ratings | **141** | 33 |
| Positive reviews | **93.7% of reviews** | 20.0% of reviews |
| In-app purchases | **No** | Yes |
| Ads | No | No |
| Update frequency | Every 5 months | **Every 2 months** |
| Monetization | **Free** | Free with in-app purchases |
| Size | 186 MB | 69 MB |
| Requires iOS | **13.0** | 15.0 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | +17 | 17+ |
| Developer | [Merck Sharp & Dohme LLC](https://appshunter.io/developer/718617686) | [Vademecum Internacional](https://appshunter.io/developer/586636217) |

## What reviewers say

### Manual MSD versión pro

[App page](https://appshunter.io/ios/app/manual-msd-version-pro/id1151854781)

This app provides medical professionals with clear, practical explanations on thousands of conditions across major medical and surgical specialties. It covers etiology, pathophysiology, prognosis, and treatment options, featuring regular updates from over 350 academic physicians.

**Highlights:** Thousands of medical topics, Regularly updated by physicians, Photos and illustrations, Instructional videos, Quizzes and medical news, Expert editorials

**Features:** macOS Compatibility

**In-app purchases:** none


### Vademecum Internacional

[App page](https://appshunter.io/ios/app/vademecum-internacional/id1449022938)

Access the most consulted pharmacological guide in Spanish, updated weekly. Analyze drug interactions, find international equivalents, and stay informed with daily news on supply issues and safety alerts. Provides detailed drug monographs for over 45 countries.

**Highlights:** Weekly updated pharmacological guide, Drug interaction analysis, International drug equivalency search, Daily news on supply and safety alerts, Detailed drug monographs, Information for over 45 countries, Prescription analysis by severity

**Features:** Vision Pro support

**In-app purchases (4)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Interacciones | $0.99 | per month |
| Vademecum | $2.49 | per month |
| Interacciones | $14.49 | per year |
| Vademecum | $28.49 | per year |


## Frequently asked questions

### Is Manual MSD versión pro free?

Manual MSD versión pro is free to download, with no in-app purchases.

### Is Vademecum Internacional free?

Vademecum Internacional is free to download, with in-app purchases available.

### Which has better reviews, Manual MSD versión pro or Vademecum Internacional?

Manual MSD versión pro is rated higher. Manual MSD versión pro averages 4.9 out of 5 from 141 ratings, while Vademecum Internacional averages 4.0 from 33 ratings.

### Do Manual MSD versión pro or Vademecum Internacional have ads?

Neither Manual MSD versión pro nor Vademecum Internacional shows ads.

### Which is updated more often, Manual MSD versión pro or Vademecum Internacional?

Manual MSD versión pro ships an update every 5 months, and Vademecum Internacional every 2 months. Most recently, Manual MSD versión pro was updated on November 2, 2026 and Vademecum Internacional on November 2, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*