# iToxin vs SMbox Neuro

The clearest difference is iOS requirement: SMbox Neuro at 9.0 against iToxin's 16.0. On price, update cadence, ads and in-app purchases there is nothing between them.

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

iToxin ships an update every 4 months, SMbox Neuro every 3 months. The most recent releases landed on October 26, 2026 and October 20, 2026 respectively.

## The numbers

| Metric | iToxin | SMbox Neuro |
| --- | --- | --- |
| Price | Free | Free |
| Positive reviews | — | 50.0% of reviews |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | Every 4 months | **Every 3 months** |
| Monetization | — | Free |
| Size | 740 MB | 19 MB |
| Requires iOS | 16.0 | **9.0** |
| Devices | iPhone, iPad | iPhone, iPod |
| Age rating | 17+ | 12+ |
| Developer | [Teracat](https://appshunter.io/developer/562843085) | [3clicks sp. z o.o.](https://appshunter.io/developer/1136238813) |

## What reviewers say

### iToxin

[App page](https://appshunter.io/ios/app/itoxin/id1197347362)

**Features:** macOS Compatibility

**In-app purchases:** none


### SMbox Neuro

[App page](https://appshunter.io/ios/app/smbox-neuro/id1381346272)

Provides healthcare professionals with quick access to essential information on diagnosing and treating multiple sclerosis. Features include diagnostic scales, treatment algorithms, drug programs, and patient materials, all updated regularly from reliable medical sources.

**Highlights:** Multiple sclerosis diagnosis and treatment information, Diagnostic and treatment scales, Drug reimbursement programs, Therapeutic algorithms, Reference centers, Conference and congress information, Patient educational materials

**Features:** macOS Compatibility

**In-app purchases:** none


## Frequently asked questions

### Is iToxin free?

iToxin is free to download, with no in-app purchases.

### Is SMbox Neuro free?

SMbox Neuro is free to download, with no in-app purchases.

### Do iToxin or SMbox Neuro have ads?

Neither iToxin nor SMbox Neuro shows ads.

### Which is updated more often, iToxin or SMbox Neuro?

iToxin ships an update every 4 months, and SMbox Neuro every 3 months. Most recently, iToxin was updated on October 26, 2026 and SMbox Neuro on October 20, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*