# Fluids and Electrolytes MIE vs NurseBrain® Synapse

The clearest difference is ads: NurseBrain® Synapse at none against Fluids and Electrolytes MIE's shown. NurseBrain® Synapse also leads on update cadence (weekly vs every 7 months) and rating (4.1 vs 3.8). Fluids and Electrolytes MIE's advantage is iOS requirement (13.0 vs 17.6). On price, in-app purchases, monetization model and device support there is nothing between them.

Both are free to download. Fluids and Electrolytes MIE sells 2 in-app purchases, starting at $39.99 per year and NurseBrain® Synapse sells 3 in-app purchases, starting at $29.99 per month. Whichever you choose, the download price is not the number that matters.

NurseBrain® Synapse holds the better App Store score, 4.1 against 3.8. That said, the two scores are not equally well evidenced: NurseBrain® Synapse has 31 ratings behind it against 5, so its average is the more settled of the two.

Fluids and Electrolytes MIE ships an update every 7 months, NurseBrain® Synapse weekly. The most recent releases landed on November 2, 2026 and November 7, 2026 respectively.

## The numbers

| Metric | Fluids and Electrolytes MIE | NurseBrain® Synapse |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [3.8 (5 ratings)](https://appshunter.io/ios/app/fluids-and-electrolytes-mie/id1207773168/reviews) | **[4.1 (31 ratings)](https://appshunter.io/ios/app/nursebrain-synapse/id1528871626/reviews)** |
| Number of ratings | 5 | **31** |
| Positive reviews | — | 85.1% of reviews |
| In-app purchases | Yes | Yes |
| Ads | Yes | **No** |
| Update frequency | Every 7 months | **Weekly** |
| Monetization | Free with in-app purchases | Free with in-app purchases |
| Best chart rank | — | **#191** |
| Size | 47 MB | 158 MB |
| Requires iOS | **13.0** | 17.6 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, Apple Watch |
| Age rating | 17+ | 17+ |
| Developer | [Skyscape Medpresso Inc](https://appshunter.io/developer/818609416) | [Nursebrain LLC](https://appshunter.io/developer/1528871628) |

## What reviewers say

### Fluids and Electrolytes MIE

[App page](https://appshunter.io/ios/app/fluids-and-electrolytes-mie/id1207773168)

This medical reference app simplifies complex fluid and electrolyte concepts for nursing professionals. It offers step-by-step guidance, visual aids, and practical tips to enhance understanding and application in patient care. Access is unlocked via an in-app purchase.

**Highlights:** Step-by-step conversational guidance, Updated nursing practices and disorders, Colorful charts and diagrams, Memory Jogger reminders, CAUTION! alerts for dangerous signs, Chart Smart documentation tips, SmartSearch technology

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Fluids & Electrolytes MIE 1//Y | $39.99 | per year |
| Fluids and Electrolytes MIE | $39.99 | one-time |


### NurseBrain® Synapse

[App page](https://appshunter.io/ios/app/nursebrain-synapse/id1528871626)

**Currently charting:** #191 Top Grossing · Medical (US App Store)

Streamline your nursing workflow with a digital report sheet. Capture patient information, tasks, and notes efficiently throughout your shift. Generate organized reports and progress notes with ease, reducing manual rewriting and saving valuable time for patient care.

**Highlights:** Customizable digital brain sheets, Organized patient tracking, Efficient shift handoffs, Voice and quick note entry, PDF export for reports, HIPAA-compliant, SBAR format organization

**Features:** Apple Watch app, Vision Pro support

**In-app purchases (3)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Monthly Premium Access | $29.99 | per month |
| Quarterly Student Access | $29.99 | per 3 months |
| Yearly Premium Access | $149.99 | per year |

**What reviewers like**

- 👍 Organizes patient info and shifts
- 👍 Improves time management
- 👍 Enhances patient care
- 👍 Minimizes charting time (AI suggestions)
- 👍 Centralized information reduces stress

**What reviewers complain about**

- 🐛 Cannot sign up/create account
- 🐛 Cannot log in after signing up
- 🐛 Annoying to not see app without paying
- 🐛 Expensive monthly/yearly fee
- 🐛 Glitches and doesn't load

**Reported bugs**

- App won't let users sign up and make an account
- Cannot log in after signing up
- App glitches and won't load
- Cannot edit active patient list
- Patient list duplicates entries

**Requested features**

- Include more specialties, specifically for outpatients
- Add a 'Return' button for new lines in text fields
- Ability to time medications
- 24-hour clock option


## Frequently asked questions

### Is Fluids and Electrolytes MIE free?

Fluids and Electrolytes MIE is free to download, with in-app purchases available.

### Is NurseBrain® Synapse free?

NurseBrain® Synapse is free to download, with in-app purchases available.

### Which has better reviews, Fluids and Electrolytes MIE or NurseBrain® Synapse?

NurseBrain® Synapse is rated higher. Fluids and Electrolytes MIE averages 3.8 out of 5 from 5 ratings, while NurseBrain® Synapse averages 4.1 from 31 ratings.

### Do Fluids and Electrolytes MIE or NurseBrain® Synapse have ads?

Fluids and Electrolytes MIE shows ads; NurseBrain® Synapse does not.

### Which is updated more often, Fluids and Electrolytes MIE or NurseBrain® Synapse?

Fluids and Electrolytes MIE ships an update every 7 months, and NurseBrain® Synapse weekly. Most recently, Fluids and Electrolytes MIE was updated on November 2, 2026 and NurseBrain® Synapse on November 7, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*