# iTIVA Anesthesia Plus vs Nerbio iTOF

The clearest difference is in-app purchases: Nerbio iTOF at none against iTIVA Anesthesia Plus's 2. Nerbio iTOF also leads on rating (5.0 vs 4.8). iTIVA Anesthesia Plus's advantage is ratings volume (330 vs 3) and iOS requirement (11.0 vs 15.6). On price, update cadence, ads and device support there is nothing between them.

Both are free to download. iTIVA Anesthesia Plus sells 2 in-app purchases, starting at $9.99 per year. Nerbio iTOF asks for nothing beyond the download.

Nerbio iTOF holds the better App Store score, 5.0 against 4.8. That said, the two scores are not equally well evidenced: iTIVA Anesthesia Plus has 330 ratings behind it against 3, so its average is the more settled of the two.

Both ship on a similar rhythm, roughly every 2 months. The most recent releases landed on September 23, 2026 and September 10, 2026 respectively.

## The numbers

| Metric | iTIVA Anesthesia Plus | Nerbio iTOF |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [4.8 (330 ratings)](https://appshunter.io/ios/app/itiva-anesthesia-plus/id1442975682/reviews) | **[5.0 (3 ratings)](https://appshunter.io/ios/app/nerbio-itof/id1525979662/reviews)** |
| Number of ratings | **330** | 3 |
| Positive reviews | 72.7% of reviews | — |
| In-app purchases | Yes | **No** |
| Ads | No | No |
| Update frequency | Every 2 months | Every 2 months |
| Monetization | Subscription | **Free** |
| Size | 125 MB | 87 MB |
| Requires iOS | **11.0** | 15.6 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [ANESTESIARTE CALI SAS](https://appshunter.io/developer/782878902) | [Nerbio Medical Software Platform Inc](https://appshunter.io/developer/1525979664) |

## What reviewers say

### iTIVA Anesthesia Plus

[App page](https://appshunter.io/ios/app/itiva-anesthesia-plus/id1442975682)

This app simulates drug concentrations in plasma and optimizes infusion schemes for medical professionals. It offers a comprehensive drug library, target-controlled infusion simulation, and MAC age calculation. Users can explore drug interactions, share cases, and export data.

**Highlights:** Accurate drug concentration estimation, Target Controlled Infusion (TCI) simulation, Comprehensive drug library (28 drugs), Explore drug interactions (70 PK, 10 PD models), MAC Age Calculation, Intraoperative milestones & case sharing, Save and run multiple simulations, Excel data export

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| iTIVA yearly | $9.99 | per year |
| iTIVA yearly 2021 | $9.99 | per year |


### Nerbio iTOF

[App page](https://appshunter.io/ios/app/nerbio-itof/id1525979662)

This medical application works with a specific device to provide quantitative monitoring of neuromuscular blocking agents. It enhances patient safety and accuracy in monitoring, offering wireless control for caregivers. The system is recommended by anesthesiologists for precise neuromuscular transmission monitoring.

**Highlights:** Quantitative neuromuscular transmission monitoring, Works with iTOF device hardware, Remote patient monitoring, Wireless control for caregivers, Automated quantitative monitoring, FDA cleared

**In-app purchases:** none


## Frequently asked questions

### Is iTIVA Anesthesia Plus free?

iTIVA Anesthesia Plus is free to download, with in-app purchases available.

### Is Nerbio iTOF free?

Nerbio iTOF is free to download, with no in-app purchases.

### Which has better reviews, iTIVA Anesthesia Plus or Nerbio iTOF?

Nerbio iTOF is rated higher. iTIVA Anesthesia Plus averages 4.8 out of 5 from 330 ratings, while Nerbio iTOF averages 5.0 from 3 ratings.

### Do iTIVA Anesthesia Plus or Nerbio iTOF have ads?

Neither iTIVA Anesthesia Plus nor Nerbio iTOF shows ads.

### Which is updated more often, iTIVA Anesthesia Plus or Nerbio iTOF?

iTIVA Anesthesia Plus ships an update every 2 months, and Nerbio iTOF every 2 months. Most recently, iTIVA Anesthesia Plus was updated on September 23, 2026 and Nerbio iTOF on September 10, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*