# iTIVA Anesthesia Plus vs Guide Dose

The clearest difference is update cadence: Guide Dose at every 5 days against iTIVA Anesthesia Plus's every 2 months. Guide Dose also leads on review sentiment (86% vs 73%). iTIVA Anesthesia Plus's advantage is iOS requirement (11.0 vs 15.5). On price, ads, in-app purchases and monetization model there is nothing between them.

Both are free to download. iTIVA Anesthesia Plus sells 2 in-app purchases, starting at $9.99 per year and Guide Dose sells 2 in-app purchases, starting at $9.99 per month. Whichever you choose, the download price is not the number that matters.

iTIVA Anesthesia Plus ships an update every 2 months, Guide Dose every 5 days. The most recent releases landed on October 16, 2026 and October 3, 2026 respectively.

## The numbers

| Metric | iTIVA Anesthesia Plus | Guide Dose |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[4.8 (330 ratings)](https://appshunter.io/ios/app/itiva-anesthesia-plus/id1442975682/reviews)** | — |
| Number of ratings | **330** | — |
| Positive reviews | 72.7% of reviews | **85.7% of reviews** |
| In-app purchases | Yes | Yes |
| Ads | No | No |
| Update frequency | Every 2 months | **Every 5 days** |
| Monetization | Subscription | Subscription |
| Size | 125 MB | 144 MB |
| Requires iOS | **11.0** | 15.5 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 12+ |
| Developer | [ANESTESIARTE CALI SAS](https://appshunter.io/developer/782878902) | [MedCalc](https://appshunter.io/developer/1699306069) |

## What reviewers say

### iTIVA Anesthesia Plus

[App page](https://appshunter.io/ios/app/itiva-anesthesia-plus/id1442975682)

This app simulates drug concentrations in plasma and optimizes infusion schemes for medical professionals. It offers a comprehensive drug library, target-controlled infusion simulation, and MAC age calculation. Users can explore drug interactions, share cases, and export data.

**Highlights:** Accurate drug concentration estimation, Target Controlled Infusion (TCI) simulation, Comprehensive drug library (28 drugs), Explore drug interactions (70 PK, 10 PD models), MAC Age Calculation, Intraoperative milestones & case sharing, Save and run multiple simulations, Excel data export

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| iTIVA yearly | $9.99 | per year |
| iTIVA yearly 2021 | $9.99 | per year |


### Guide Dose

[App page](https://appshunter.io/ios/app/guide-dose-for-physicians/id6453359266)

This app provides healthcare professionals and students with quick access to clinical information, drug doses, and decision-support tools. It features a structured experience for study, reference, and organizing medical data, including AI-powered informational support.

**Highlights:** Search by medication or indication, Patient profile for contextualized readings, Organized clinical references and labeling, Modules on physiology, medications, and CPR, Clinical AI for informational support, Protocols and consultation flows, Auxiliary clinical tools

**Features:** macOS Compatibility

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Guide Dose Pro (monthly) | $9.99 | per month |
| Guide Dose Pro (annual) | $69.99 | per year |


## Frequently asked questions

### Is iTIVA Anesthesia Plus free?

iTIVA Anesthesia Plus is free to download, with in-app purchases available.

### Is Guide Dose free?

Guide Dose is free to download, with in-app purchases available.

### Do iTIVA Anesthesia Plus or Guide Dose have ads?

Neither iTIVA Anesthesia Plus nor Guide Dose shows ads.

### Which is updated more often, iTIVA Anesthesia Plus or Guide Dose?

iTIVA Anesthesia Plus ships an update every 2 months, and Guide Dose every 5 days. Most recently, iTIVA Anesthesia Plus was updated on October 16, 2026 and Guide Dose on October 3, 2026.

---

*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*