# iTIVA Anesthesia Plus vs Safe Vent

The clearest difference is iOS requirement: iTIVA Anesthesia Plus at 11.0 against Safe Vent's 13.0. On price, update cadence, ads and in-app purchases there is nothing between them.

Both are free to download. iTIVA Anesthesia Plus sells 2 in-app purchases, starting at $9.99 per year and Safe Vent sells 2 in-app purchases, starting at $2.99 per month. Whichever you choose, the download price is not the number that matters.

iTIVA Anesthesia Plus ships an update every 2 months, Safe Vent every 3 months. The most recent releases landed on September 23, 2026 and September 11, 2026 respectively.

## The numbers

| Metric | iTIVA Anesthesia Plus | Safe Vent |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[4.8 (330 ratings)](https://appshunter.io/ios/app/itiva-anesthesia-plus/id1442975682/reviews)** | — |
| Number of ratings | **330** | — |
| Positive reviews | 72.7% of reviews | — |
| In-app purchases | Yes | Yes |
| Ads | No | No |
| Update frequency | **Every 2 months** | Every 3 months |
| Monetization | Subscription | — |
| Size | 125 MB | 58 MB |
| Requires iOS | **11.0** | 13.0 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [ANESTESIARTE CALI SAS](https://appshunter.io/developer/782878902) | [SYNAPS AI SAS](https://appshunter.io/developer/1710831235) |

## What reviewers say

### iTIVA Anesthesia Plus

[App page](https://appshunter.io/ios/app/itiva-anesthesia-plus/id1442975682)

This app simulates drug concentrations in plasma and optimizes infusion schemes for medical professionals. It offers a comprehensive drug library, target-controlled infusion simulation, and MAC age calculation. Users can explore drug interactions, share cases, and export data.

**Highlights:** Accurate drug concentration estimation, Target Controlled Infusion (TCI) simulation, Comprehensive drug library (28 drugs), Explore drug interactions (70 PK, 10 PD models), MAC Age Calculation, Intraoperative milestones & case sharing, Save and run multiple simulations, Excel data export

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| iTIVA yearly | $9.99 | per year |
| iTIVA yearly 2021 | $9.99 | per year |


### Safe Vent

[App page](https://appshunter.io/ios/app/safe-vent/id6468893543)

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Safe Vent Full Access | $2.99 | per month |
| Safe Vent Full Access | $29.99 | per year |


## Frequently asked questions

### Is iTIVA Anesthesia Plus free?

iTIVA Anesthesia Plus is free to download, with in-app purchases available.

### Is Safe Vent free?

Safe Vent is free to download, with in-app purchases available.

### Do iTIVA Anesthesia Plus or Safe Vent have ads?

Neither iTIVA Anesthesia Plus nor Safe Vent shows ads.

### Which is updated more often, iTIVA Anesthesia Plus or Safe Vent?

iTIVA Anesthesia Plus ships an update every 2 months, and Safe Vent every 3 months. Most recently, iTIVA Anesthesia Plus was updated on September 23, 2026 and Safe Vent on September 11, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*