# APLIGEM vs AntibioticApp

The clearest difference is in-app purchases: APLIGEM at none against AntibioticApp's 2. APLIGEM also leads on ads (none vs shown) and update cadence (every 2 weeks vs every 4 months). On price and device support there is nothing between them.

Both are free to download. AntibioticApp sells 2 in-app purchases, starting at $0.99 per month. APLIGEM asks for nothing beyond the download.

APLIGEM ships an update every 2 weeks, AntibioticApp every 4 months. The most recent releases landed on September 20, 2026 and September 17, 2026 respectively.

## The numbers

| Metric | APLIGEM | AntibioticApp |
| --- | --- | --- |
| Price | Free | Free |
| Rating | — | **[5.0 (3 ratings)](https://appshunter.io/ios/app/antibioticapp/id1510630035/reviews)** |
| Number of ratings | — | **3** |
| In-app purchases | **No** | Yes |
| Ads | **No** | Yes |
| Update frequency | **Every 2 weeks** | Every 4 months |
| Monetization | — | Free with in-app purchases |
| Size | 60 MB | 46 MB |
| Requires iOS | **12.0** | 15.6 |
| Devices | **iPhone, iPad, iPod** | iPhone, iPod |
| Age rating | 12+ | 17+ |
| Developer | [ACTIVIA SA](https://appshunter.io/developer/1449162015) | [Screaming Brothers S.A.](https://appshunter.io/developer/1593875614) |

## What reviewers say

### APLIGEM

[App page](https://appshunter.io/ios/app/apligem/id1449162016)

**Features:** Vision Pro support

**In-app purchases:** none


### AntibioticApp

[App page](https://appshunter.io/ios/app/antibioticapp/id1510630035)

A practical, synthetic, and reliable tool for healthcare professionals to improve antimicrobial use. It provides updated information on infectious diseases, therapeutic recommendations, vaccines, infection control, and pharmacological/microbiological data.

**Highlights:** Antimicrobial treatments and prophylaxis, Antimicrobial drug compendium, Updated microbiological and parasitological data, Infectious disease information, Vaccine recommendations, Infection control guidelines, Intuitive menus and search engine

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Apprentice | $0.99 | per month |
| Apprentice | $9.99 | per year |


## Frequently asked questions

### Is APLIGEM free?

APLIGEM is free to download, with no in-app purchases.

### Is AntibioticApp free?

AntibioticApp is free to download, with in-app purchases available.

### Do APLIGEM or AntibioticApp have ads?

AntibioticApp shows ads; APLIGEM does not.

### Which is updated more often, APLIGEM or AntibioticApp?

APLIGEM ships an update every 2 weeks, and AntibioticApp every 4 months. Most recently, APLIGEM was updated on September 20, 2026 and AntibioticApp on September 17, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*