# MD Reference vs misTMJ

The clearest difference is in-app purchases: misTMJ at none against MD Reference's 4. misTMJ also leads on ads (none vs shown) and update cadence (monthly vs every 4 months). On price, device support and iOS requirement there is nothing between them.

Both are free to download. MD Reference sells 4 in-app purchases, starting at $2.99 per month. misTMJ asks for nothing beyond the download.

MD Reference ships an update every 4 months, misTMJ monthly. The most recent releases landed on July 16, 2026 and September 18, 2026 respectively.

## The numbers

| Metric | MD Reference | misTMJ |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[3.0 (2 ratings)](https://appshunter.io/ios/app/md-reference/id1509330680/reviews)** | — |
| Number of ratings | **2** | — |
| Positive reviews | 50.0% of reviews | — |
| In-app purchases | Yes | **No** |
| Ads | Yes | **No** |
| Update frequency | Every 4 months | **Monthly** |
| Monetization | Free with in-app purchases | — |
| Size | 14 MB | 594 MB |
| Requires iOS | **10.0** | 11.0 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [Uptodate In Medicine MMC](https://appshunter.io/developer/1428873400) | [Himalaya Computing](https://appshunter.io/developer/1205321932) |

## What reviewers say

### MD Reference

[App page](https://appshunter.io/ios/app/md-reference/id1509330680)

This medical reference app aims to improve healthcare quality by providing medical professionals with updated knowledge and modern technologies. It helps practitioners stay informed about advancements and apply them in their practice. The service operates on a subscription basis with various plans available.

**Highlights:** Enhances medical knowledge, Keeps users updated on new technologies, Facilitates practical application of knowledge, Subscription-based access, Personalized user accounts

**Features:** macOS Compatibility

**In-app purchases (4)**

| Purchase | Price | Billing |
| --- | --- | --- |
| 1 month subscription | $2.99 | per month |
| 3 months subscription | $8.99 | per 3 months |
| 6 months subscription | $14.99 | per 6 months |
| 12 months subscription | $23.99 | per year |


### misTMJ

[App page](https://appshunter.io/ios/app/mistmj/id1592838220)

**Features:** macOS Compatibility

**In-app purchases:** none


## Frequently asked questions

### Is MD Reference free?

MD Reference is free to download, with in-app purchases available.

### Is misTMJ free?

misTMJ is free to download, with no in-app purchases.

### Do MD Reference or misTMJ have ads?

MD Reference shows ads; misTMJ does not.

### Which is updated more often, MD Reference or misTMJ?

MD Reference ships an update every 4 months, and misTMJ monthly. Most recently, MD Reference was updated on July 16, 2026 and misTMJ on September 18, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*