# Eterna vs DNA Mutations Puzzles

The clearest difference is rating: Eterna at 3.7 against DNA Mutations Puzzles's 3.0. Eterna also leads on in-app purchases (none vs 1) and ads (none vs shown). DNA Mutations Puzzles's advantage is review sentiment (50% vs 33%) and iOS requirement (8.0 vs 13.0). On price, update cadence and device support there is nothing between them.

Both are free to download. DNA Mutations Puzzles sells 1 one-off in-app purchase. Eterna asks for nothing beyond the download.

Eterna holds the better App Store score, 3.7 against 3.0. Both are backed by a comparable volume of ratings — 15 and 4 respectively. Written reviews complicate that: 33% of Eterna's written reviews are positive against 50% of DNA Mutations Puzzles's, so the app with the better star average is not the one people write more warmly about.

Both ship on a similar rhythm, roughly every 3 weeks. The most recent releases landed on September 17, 2026 and August 13, 2026 respectively.

## The numbers

| Metric | Eterna | DNA Mutations Puzzles |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[3.7 (15 ratings)](https://appshunter.io/ios/app/eterna/id1513216417/reviews)** | [3.0 (4 ratings)](https://appshunter.io/ios/app/dna-mutations-puzzles/id1550067719/reviews) |
| Number of ratings | **15** | 4 |
| Positive reviews | 33.3% of reviews | **50.0% of reviews** |
| In-app purchases | **No** | Yes |
| Ads | **No** | Yes |
| Update frequency | Every 3 weeks | Every 3 weeks |
| Monetization | **Free** | Free with in-app purchases |
| Size | 188 MB | 32 MB |
| Requires iOS | 13.0 | **8.0** |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 12+ | 4+ |
| Developer | [Vital Mind Media](https://appshunter.io/developer/1513216416) | [Frozax Games](https://appshunter.io/developer/510201851) |

## What reviewers say

### Eterna

[App page](https://appshunter.io/ios/app/eterna/id1513216417)

Engage in a citizen science game to design RNA molecules for medical research. Solve puzzles to unlock lab access and contribute to inventing new medicines through challenges.

**Highlights:** Design RNA molecules, Solve scientific puzzles, Participate in medical research, Invent new medicines, Unlock lab access

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


### DNA Mutations Puzzles

[App page](https://appshunter.io/ios/app/dna-mutations-puzzles/id1550067719)

A retro puzzle game where players modify DNA sequences to match a target. Utilize a limited number of mutations in any order to solve scientific challenges. Enjoy an intuitive, colorful pixel-art experience that can be played offline.

**Highlights:** DNA modification gameplay, Limited mutation challenges, Retro pixel-art design, Intuitive controls, Offline play available, Multiple difficulty levels

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Remove Ads | $2.99 | one-time |


## Frequently asked questions

### Is Eterna free?

Eterna is free to download, with no in-app purchases.

### Is DNA Mutations Puzzles free?

DNA Mutations Puzzles is free to download, with in-app purchases available.

### Which has better reviews, Eterna or DNA Mutations Puzzles?

Eterna is rated higher. Eterna averages 3.7 out of 5 from 15 ratings, while DNA Mutations Puzzles averages 3.0 from 4 ratings.

### Do Eterna or DNA Mutations Puzzles have ads?

DNA Mutations Puzzles shows ads; Eterna does not.

### Which is updated more often, Eterna or DNA Mutations Puzzles?

Eterna ships an update every 3 weeks, and DNA Mutations Puzzles every 3 weeks. Most recently, Eterna was updated on September 17, 2026 and DNA Mutations Puzzles on August 13, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*