# Eterna vs Total Biochem

The clearest difference is rating: Total Biochem at 5.0 against Eterna's 3.7. Total Biochem also leads on update cadence (weekly vs every 3 weeks). Eterna's advantage is in-app purchases (none vs 1) and ratings volume (15 vs 1). On price, ads and device support there is nothing between them.

Both are free to download. Total Biochem sells 1 one-off in-app purchase. Eterna asks for nothing beyond the download.

Total Biochem holds the better App Store score, 5.0 against 3.7. That said, the two scores are not equally well evidenced: Eterna has 15 ratings behind it against 1, so its average is the more settled of the two.

Eterna ships an update every 3 weeks, Total Biochem weekly. Both last shipped on October 24, 2026.

## The numbers

| Metric | Eterna | Total Biochem |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [3.7 (15 ratings)](https://appshunter.io/ios/app/eterna/id1513216417/reviews) | **[5.0 (1 ratings)](https://appshunter.io/ios/app/total-biochem/id6809552525/reviews)** |
| Number of ratings | **15** | 1 |
| Positive reviews | 33.3% of reviews | — |
| In-app purchases | **No** | Yes |
| Ads | No | No |
| Update frequency | Every 3 weeks | **Weekly** |
| Monetization | **Free** | Free with in-app purchases |
| Size | 188 MB | 63 MB |
| Requires iOS | **13.0** | 15.1 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 12+ | 4+ |
| Developer | [Vital Mind Media](https://appshunter.io/developer/1513216416) | [Sinter Labs LLC](https://appshunter.io/developer/6796522374) |

## What reviewers say

### Eterna

[App page](https://appshunter.io/ios/app/eterna/id1513216417)

Engage in a citizen science game to design RNA molecules for medical research. Solve puzzles to unlock lab access and contribute to inventing new medicines through challenges.

**Highlights:** Design RNA molecules, Solve scientific puzzles, Participate in medical research, Invent new medicines, Unlock lab access

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


### Total Biochem

[App page](https://appshunter.io/ios/app/total-biochem/id6809552525)

Master biochemistry with comprehensive study tools, including practice questions, lessons, flashcards, and mock exams. Then, apply your knowledge in a captivating night-shift mystery game where you diagnose patients by analyzing lab results and biochemical pathways.

**Highlights:** 3,300+ Practice Items, Lessons for Every Topic, Flashcards & Cheat Sheets, Mock Exams & Course Map, Step-by-step Mechanism Walkthroughs, Clinical Mystery Game, Lab Analysis Simulation

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Full Game | $4.99 | one-time |


## Frequently asked questions

### Is Eterna free?

Eterna is free to download, with no in-app purchases.

### Is Total Biochem free?

Total Biochem is free to download, with in-app purchases available.

### Which has better reviews, Eterna or Total Biochem?

Total Biochem is rated higher. Eterna averages 3.7 out of 5 from 15 ratings, while Total Biochem averages 5.0 from 1 ratings.

### Do Eterna or Total Biochem have ads?

Neither Eterna nor Total Biochem shows ads.

### Which is updated more often, Eterna or Total Biochem?

Eterna ships an update every 3 weeks, and Total Biochem weekly. Most recently, Eterna was updated on October 24, 2026 and Total Biochem on October 24, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*