# iSearch Science vs ResearchGuide

The clearest difference is in-app purchases: ResearchGuide at none against iSearch Science's 8. ResearchGuide also leads on update cadence (every 3 days vs every 3 weeks) and iOS requirement (13.0 vs 16.0). On price, ads and device support there is nothing between them.

Both are free to download. iSearch Science sells 8 in-app purchases, starting at $7.99 per month. ResearchGuide asks for nothing beyond the download.

iSearch Science ships an update every 3 weeks, ResearchGuide every 3 days. The most recent releases landed on October 11, 2026 and October 9, 2026 respectively.

## The numbers

| Metric | iSearch Science | ResearchGuide |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[3.2 (13 ratings)](https://appshunter.io/ios/app/isearch-science/id1516874861/reviews)** | — |
| Number of ratings | **13** | — |
| Positive reviews | 84.2% of reviews | — |
| In-app purchases | Yes | **No** |
| Ads | No | No |
| Update frequency | Every 3 weeks | **Every 3 days** |
| Monetization | Free with in-app purchases | — |
| Size | 39 MB | 17 MB |
| Requires iOS | 16.0 | **13.0** |
| Devices | iPhone, iPad, Mac | iPhone, iPad, iPod |
| Age rating | 12+ | 17+ |
| Developer | [Best Surgical Education, LLC](https://appshunter.io/developer/1331613158) | [Monark IT](https://appshunter.io/developer/1618583329) |

## What reviewers say

### iSearch Science

[App page](https://appshunter.io/ios/app/isearch-science/id1516874861)

This intelligent research assistant mines the web for studies, automatically refining searches and classifying results by type. It uses AI to identify entities like drugs and diseases, and can summarize content or answer questions about research findings.

**Highlights:** Automated query refinement, Study classification by type, Entity identification (drugs, diseases), AI-powered summarization, Question answering on search results, PDF content analysis

**In-app purchases (8)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Monthly Subscription - Basic | $7.99 | per month |
| Monthly Subscription-Advanced | $12.99 | per month |
| Yearly Subscription - Basic | $39.99 | per year |
| Yearly Subscription - Advanced | $44.99 | per year |
| Full Access to Mac + iOS | $49.99 | per year |
| Cross Platform + Healthcare | $74.99 | per year |
| iSearch Science,iSearch Biomed | $99.99 | per year |
| Purchase Healthcare API | $24.99 | one-time |


### ResearchGuide

[App page](https://appshunter.io/ios/app/researchguide/id6477701498)

**Features:** macOS Compatibility

**In-app purchases:** none


## Frequently asked questions

### Is iSearch Science free?

iSearch Science is free to download, with in-app purchases available.

### Is ResearchGuide free?

ResearchGuide is free to download, with no in-app purchases.

### Do iSearch Science or ResearchGuide have ads?

Neither iSearch Science nor ResearchGuide shows ads.

### Which is updated more often, iSearch Science or ResearchGuide?

iSearch Science ships an update every 3 weeks, and ResearchGuide every 3 days. Most recently, iSearch Science was updated on October 11, 2026 and ResearchGuide on October 9, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*