# Codon One vs BioCaL

The clearest difference is update cadence: BioCaL at every 2 days against Codon One's every 3 weeks. Codon One's advantage is iOS requirement (15.6 vs 17.0). On price, ads, in-app purchases and device support there is nothing between them.

Both are free to download. Codon One sells 7 one-off in-app purchases and BioCaL sells 1 one-off in-app purchase. Whichever you choose, the download price is not the number that matters.

Codon One ships an update every 3 weeks, BioCaL every 2 days. The most recent releases landed on September 8, 2026 and August 2, 2026 respectively.

## The numbers

| Metric | Codon One | BioCaL |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[4.4 (23 ratings)](https://appshunter.io/ios/app/codon-one-biology-study/id1517313390/reviews)** | — |
| Number of ratings | **23** | — |
| Positive reviews | 76.5% of reviews | — |
| In-app purchases | Yes | Yes |
| Ads | No | No |
| Update frequency | Every 3 weeks | **Every 2 days** |
| Monetization | Free with in-app purchases | — |
| Size | 252 MB | 23 MB |
| Requires iOS | **15.6** | 17.0 |
| Devices | **iPhone, iPad, iPod** | iPhone, iPad |
| Age rating | 4+ | 4+ |
| Developer | [Daniel Gebert](https://appshunter.io/developer/1517313389) | [Yoshikazu Mikawa](https://appshunter.io/developer/1778069380) |

## What reviewers say

### Codon One

[App page](https://appshunter.io/ios/app/codon-one-biology-study/id1517313390)

Master molecular biology, genetics, evolution, and life chemistry through interactive modules and quizzes. Explore essential concepts with clear diagrams and concise explanations. Includes helpful tools for sequence analysis and genetic code reference.

**Highlights:** Interactive learning modules, Quick quizzes for comprehension, Clear diagrams and plain language, Molecule reference guide, Sequence analysis tools, Genetic code exploration

**Features:** Family Sharing, Vision Pro support

**In-app purchases (7)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Module 1: Chemistry of Life | Free | one-time |
| Module 2: Genetics | $2.99 | one-time |
| Module 3: Evolution | $2.99 | one-time |
| Module 4: Science History | $2.99 | one-time |
| Module 5: Cell Biology | $2.99 | one-time |
| Module 6: Development | $2.99 | one-time |
| Unlock All | $8.99 | one-time |


### BioCaL

[App page](https://appshunter.io/ios/app/biocal/id6476985449)

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| BioCaL Premium Access | $4.99 | one-time |


## Frequently asked questions

### Is Codon One free?

Codon One is free to download, with in-app purchases available.

### Is BioCaL free?

BioCaL is free to download, with in-app purchases available.

### Do Codon One or BioCaL have ads?

Neither Codon One nor BioCaL shows ads.

### Which is updated more often, Codon One or BioCaL?

Codon One ships an update every 3 weeks, and BioCaL every 2 days. Most recently, Codon One was updated on September 8, 2026 and BioCaL on August 2, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*