# Pyrls vs Antibiotics Simplified Guide

The clearest difference is ads: Pyrls at none against Antibiotics Simplified Guide's shown. Pyrls also leads on update cadence (every 9 days vs every 2 months) and chart position (#65 vs unranked). On price, in-app purchases, device support and iOS requirement there is nothing between them.

Both are free to download. Pyrls sells 3 in-app purchases, starting at $40.00 per month and Antibiotics Simplified Guide sells 1 in-app purchase, starting at $9.99 per year. Whichever you choose, the download price is not the number that matters.

Pyrls ships an update every 9 days, Antibiotics Simplified Guide every 2 months. The most recent releases landed on November 7, 2026 and November 8, 2026 respectively.

## The numbers

| Metric | Pyrls | Antibiotics Simplified Guide |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[4.8 (136 ratings)](https://appshunter.io/ios/app/pyrls/id1517540628/reviews)** | — |
| Number of ratings | **136** | — |
| Positive reviews | 82.4% of reviews | — |
| In-app purchases | Yes | Yes |
| Ads | **No** | Yes |
| Update frequency | **Every 9 days** | Every 2 months |
| Monetization | Free with in-app purchases | — |
| Best chart rank | **#65** | — |
| Size | 80 MB | 48 MB |
| Requires iOS | 13.0 | 13.0 |
| Devices | iPhone, iPod | **iPhone, iPad, iPod** |
| Age rating | 17+ | 17+ |
| Developer | [Cosmas Health LLC](https://appshunter.io/developer/1517540627) | [Skyscape Medpresso Inc](https://appshunter.io/developer/818609416) |

## What reviewers say

### Pyrls

[App page](https://appshunter.io/ios/app/pyrls/id1517540628)

**Currently charting:** #65 Top Grossing · Medical (US App Store)

This app provides essential drug information for medical professionals, focusing on practical details like indications, pharmacology, and counseling points. It offers quick access to key data, reference tables, and clinical pearls to aid in medication management and patient care.

**Highlights:** Drug naming and indications, Pharmacology details, Counseling points, Safety and monitoring information, Reference tables and charts

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (3)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Pyrls Monthly Membership | $40.00 | per month |
| Annual: Student/New Provider | $119.99 | per year |
| Annual: Professional | $179.99 | per year |

**What reviewers like**

- 👍 Easy to use and navigate
- 💡 Excellent resource for drug information
- 📊 Fantastic charts and summaries
- 📚 Helpful for students and practitioners
- 🚀 Quick access to information

**What reviewers complain about**

- 📉 Incomplete drug database
- 💰 Expensive subscription for some
- ❓ Some users experience issues with free content

**Reported bugs**

- Free NAPLEX questions do not open
- App does not open

**Requested features**

- iPad mini support
- Fund business outside of user subscriptions


### Antibiotics Simplified Guide

[App page](https://appshunter.io/ios/app/antibiotics-simplified-guide/id6741313363)

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Antibiotics Simplified 1/Y Sub | $9.99 | per year |


## Frequently asked questions

### Is Pyrls free?

Pyrls is free to download, with in-app purchases available.

### Is Antibiotics Simplified Guide free?

Antibiotics Simplified Guide is free to download, with in-app purchases available.

### Do Pyrls or Antibiotics Simplified Guide have ads?

Antibiotics Simplified Guide shows ads; Pyrls does not.

### Which is updated more often, Pyrls or Antibiotics Simplified Guide?

Pyrls ships an update every 9 days, and Antibiotics Simplified Guide every 2 months. Most recently, Pyrls was updated on November 7, 2026 and Antibiotics Simplified Guide on November 8, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*