# TrialOnline vs YPrime eCOA

The clearest difference is rating: YPrime eCOA at 2.9 against TrialOnline's 2.5. YPrime eCOA also leads on review sentiment (13% vs 0%) and ratings volume (15 vs 2). On price, update cadence, ads and in-app purchases there is nothing between them.

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

YPrime eCOA holds the better App Store score, 2.9 against 2.5. That said, the two scores are not equally well evidenced: YPrime eCOA has 15 ratings behind it against 2, so its average is the more settled of the two. Written reviews point the same way: 0% of TrialOnline's written reviews are positive against 13% of YPrime eCOA's.

TrialOnline ships an update every 3 months, YPrime eCOA every 2 months. The most recent releases landed on October 18, 2026 and October 24, 2026 respectively.

## The numbers

| Metric | TrialOnline | YPrime eCOA |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [2.5 (2 ratings)](https://appshunter.io/ios/app/trialonline/id1521167087/reviews) | **[2.9 (15 ratings)](https://appshunter.io/ios/app/yprime-ecoa/id1521277112/reviews)** |
| Number of ratings | 2 | **15** |
| Positive reviews | 0.0% of reviews | **12.5% of reviews** |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | Every 3 months | **Every 2 months** |
| Monetization | Free | Free |
| Size | 71 MB | 131 MB |
| Requires iOS | **11.0** | 12.0 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 4+ |
| Developer | [Replior AB](https://appshunter.io/developer/1513532149) | [Y-Prime](https://appshunter.io/developer/872635320) |

## What reviewers say

### TrialOnline

[App page](https://appshunter.io/ios/app/trialonline/id1521167087)

This application serves as a patient portal for clinical research participants, allowing them to complete study-specific questionnaires and communicate with healthcare personnel. It facilitates secure data gathering and ensures patient anonymity throughout clinical trials, adhering to international regulations.

**Highlights:** Patient portal for clinical research, Study-specific questionnaires, Secure data gathering, Patient anonymity, Video, voice, and text communication, Site-to-patient communication module

**In-app purchases:** none


### YPrime eCOA

[App page](https://appshunter.io/ios/app/yprime-ecoa/id1521277112)

Access clinical study questionnaires on your personal device. Use your enrollment ID to log in and complete required training. The app reminds you of upcoming questionnaires based on your visit schedule, ensuring compliance with study requirements.

**Highlights:** Access study questionnaires, Personal device access, Enrollment ID login, Study-specific questionnaires, Visit schedule reminders, Compliance tracking

**In-app purchases:** none


## Frequently asked questions

### Is TrialOnline free?

TrialOnline is free to download, with no in-app purchases.

### Is YPrime eCOA free?

YPrime eCOA is free to download, with no in-app purchases.

### Which has better reviews, TrialOnline or YPrime eCOA?

YPrime eCOA is rated higher. TrialOnline averages 2.5 out of 5 from 2 ratings, while YPrime eCOA averages 2.9 from 15 ratings.

### Do TrialOnline or YPrime eCOA have ads?

Neither TrialOnline nor YPrime eCOA shows ads.

### Which is updated more often, TrialOnline or YPrime eCOA?

TrialOnline ships an update every 3 months, and YPrime eCOA every 2 months. Most recently, TrialOnline was updated on October 18, 2026 and YPrime eCOA on October 24, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*