# NurseBrain® Synapse vs Nursing Constellation Plus+

The clearest difference is ads: NurseBrain® Synapse at none against Nursing Constellation Plus+'s shown. NurseBrain® Synapse also leads on update cadence (weekly vs every 20 months) and ratings volume (31 vs 9). Nursing Constellation Plus+'s advantage is rating (4.6 vs 4.1) and review sentiment (100% vs 85%). On price, in-app purchases, monetization model and device support there is nothing between them.

Both are free to download. NurseBrain® Synapse sells 3 in-app purchases, starting at $29.99 per month and Nursing Constellation Plus+ sells 11 one-off in-app purchases. Whichever you choose, the download price is not the number that matters.

Nursing Constellation Plus+ holds the better App Store score, 4.6 against 4.1. Both are backed by a comparable volume of ratings — 31 and 9 respectively. Written reviews point the same way: 85% of NurseBrain® Synapse's written reviews are positive against 100% of Nursing Constellation Plus+'s.

NurseBrain® Synapse ships an update weekly, Nursing Constellation Plus+ every 20 months. The most recent releases landed on October 20, 2026 and October 2, 2026 respectively.

## The numbers

| Metric | NurseBrain® Synapse | Nursing Constellation Plus+ |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [4.1 (31 ratings)](https://appshunter.io/ios/app/nursebrain-synapse/id1528871626/reviews) | **[4.6 (9 ratings)](https://appshunter.io/ios/app/nursing-constellation-plus-plus/id1601814490/reviews)** |
| Number of ratings | **31** | 9 |
| Positive reviews | 85.1% of reviews | **100.0% of reviews** |
| In-app purchases | Yes | Yes |
| Ads | **No** | Yes |
| Update frequency | **Weekly** | Every 20 months |
| Monetization | Free with in-app purchases | Free with in-app purchases |
| Size | 146 MB | 42 MB |
| Requires iOS | 17.6 | **13.0** |
| Devices | iPhone, iPad, Apple Watch | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [Nursebrain LLC](https://appshunter.io/developer/1528871628) | [Skyscape Medpresso Inc](https://appshunter.io/developer/818609416) |

## What reviewers say

### NurseBrain® Synapse

[App page](https://appshunter.io/ios/app/nursebrain-synapse/id1528871626)

This app digitizes nursing report sheets, allowing nurses to manage their entire shift from a single, connected platform. It helps organize patient information, tasks, and notes, facilitating confident handoffs and efficient documentation.

**Highlights:** Customizable digital brain sheets, Real-time shift tracking, Organized patient handoff views, Voice and quick entry documentation, Generate progress notes and care plans, Cross-device compatibility (phone, watch)

**Features:** Apple Watch app, Vision Pro support

**In-app purchases (3)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Monthly Premium Access | $29.99 | per month |
| Quarterly Student Access | $29.99 | per 3 months |
| Yearly Premium Access | $149.99 | per year |

**What reviewers like**

- 👍 Organizes patient info and shifts
- 👍 Improves time management
- 👍 Enhances patient care
- 👍 Minimizes charting time (AI suggestions)
- 👍 Centralized information reduces stress

**What reviewers complain about**

- 🐛 Cannot sign up/create account
- 🐛 Cannot log in after signing up
- 🐛 Annoying to not see app without paying
- 🐛 Expensive monthly/yearly fee
- 🐛 Glitches and doesn't load

**Reported bugs**

- App won't let users sign up and make an account
- Cannot log in after signing up
- App glitches and won't load
- Cannot edit active patient list
- Patient list duplicates entries

**Requested features**

- Include more specialties, specifically for outpatients
- Add a 'Return' button for new lines in text fields
- Ability to time medications
- 24-hour clock option


### Nursing Constellation Plus+

[App page](https://appshunter.io/ios/app/nursing-constellation-plus-plus/id1601814490)

This app integrates seven essential mobile nursing references, offering comprehensive information on drugs, diseases, lab tests, and procedures. It provides clinical decision support for nurses and students at the bedside, in class, or during simulations.

**Highlights:** 7 integrated nursing references, Drug guide with 5,000+ medications, Disease and disorder information, Laboratory and diagnostic test details, Medical calculator, Medical news updates

**Features:** macOS Compatibility

**In-app purchases (11)**

| Purchase | Price | Billing |
| --- | --- | --- |
| ICD10-Clinical Modification 25 | $1.99 | one-time |
| ICD10-Clinical Modification 24 | $1.99 | one-time |
| Skyscape Clinical Calc PLUS | $24.99 | one-time |
| RNotes® Nurse's Pkt Guide Ed.6 | $29.99 | one-time |
| Taber's Dictionary - ed.25 | $38.99 | one-time |
| Taber's Dictionary - ed.24 | $38.99 | one-time |
| Davis DrugGuide-Nurses 24 ed19 | $47.99 | one-time |
| HBK of Laboratory & Dx Tests | $54.99 | one-time |
| HBK of Laboratory and Dx Tests | $54.99 | one-time |
| Diseases and Disorders FADavis | $59.99 | one-time |
| Nursing Constellation Plus | $179.99 | one-time |


## Frequently asked questions

### Is NurseBrain® Synapse free?

NurseBrain® Synapse is free to download, with in-app purchases available.

### Is Nursing Constellation Plus+ free?

Nursing Constellation Plus+ is free to download, with in-app purchases available.

### Which has better reviews, NurseBrain® Synapse or Nursing Constellation Plus+?

Nursing Constellation Plus+ is rated higher. NurseBrain® Synapse averages 4.1 out of 5 from 31 ratings, while Nursing Constellation Plus+ averages 4.6 from 9 ratings.

### Do NurseBrain® Synapse or Nursing Constellation Plus+ have ads?

Nursing Constellation Plus+ shows ads; NurseBrain® Synapse does not.

### Which is updated more often, NurseBrain® Synapse or Nursing Constellation Plus+?

NurseBrain® Synapse ships an update weekly, and Nursing Constellation Plus+ every 20 months. Most recently, NurseBrain® Synapse was updated on October 20, 2026 and Nursing Constellation Plus+ on October 2, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*