# Справочник MSD профи vs SYNAPSE I СИНАПС

The clearest difference is in-app purchases: Справочник MSD профи at none against SYNAPSE I СИНАПС's 3. Справочник MSD профи also leads on iOS requirement (13.0 vs 15.0). SYNAPSE I СИНАПС's advantage is update cadence (monthly vs every 7 months) and review sentiment (100% vs 89%). On price, ads and device support there is nothing between them.

Both are free to download. SYNAPSE I СИНАПС sells 3 in-app purchases, starting at $12.99 per month. Справочник MSD профи asks for nothing beyond the download.

Справочник MSD профи ships an update every 7 months, SYNAPSE I СИНАПС monthly. The most recent releases landed on September 24, 2026 and September 15, 2026 respectively.

## The numbers

| Metric | Справочник MSD профи | SYNAPSE I СИНАПС |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[4.9 (7 ratings)](https://appshunter.io/ios/app/msd/id1547442149/reviews)** | — |
| Number of ratings | **7** | — |
| Positive reviews | 88.7% of reviews | **100.0% of reviews** |
| In-app purchases | **No** | Yes |
| Ads | No | No |
| Update frequency | Every 7 months | **Monthly** |
| Monetization | **Free** | Free with in-app purchases |
| Size | 205 MB | 24 MB |
| Requires iOS | **13.0** | 15.0 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [Merck Sharp & Dohme LLC](https://appshunter.io/developer/718617686) | [Dmitry Tereshin](https://appshunter.io/developer/1774693004) |

## What reviewers say

### Справочник MSD профи

[App page](https://appshunter.io/ios/app/msd/id1547442149)

This app provides medical professionals with comprehensive, up-to-date information on thousands of diseases and conditions across all major medical and surgical fields. It includes detailed explanations, images, videos, and self-assessment tests for continuous learning and practice.

**Highlights:** Thousands of diseases and conditions covered, Regularly updated clinical information, Images and illustrations of pathologies, Video guides for procedures and exams, Self-assessment tests, Medical news and expert commentary

**Features:** macOS Compatibility

**In-app purchases:** none


### SYNAPSE I СИНАПС

[App page](https://appshunter.io/ios/app/synapse-i/id6737121601)

This app provides a comprehensive medical knowledge base with articles, clinical case studies, and video courses for healthcare professionals. It offers tools like calculators and scales to aid in clinical practice and learning.

**Highlights:** Extensive medical article database, Interactive clinical case studies, Video courses from experts, Clinical calculators and scales, Preparation for international exams, Medical English learning

**Features:** macOS Compatibility

**In-app purchases (3)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Подписка на 1 месяц | $12.99 | per month |
| Подписка на 3 месяца | $34.99 | per 3 months |
| Подписка на 12 месяцев | $129.99 | per year |


## Frequently asked questions

### Is Справочник MSD профи free?

Справочник MSD профи is free to download, with no in-app purchases.

### Is SYNAPSE I СИНАПС free?

SYNAPSE I СИНАПС is free to download, with in-app purchases available.

### Do Справочник MSD профи or SYNAPSE I СИНАПС have ads?

Neither Справочник MSD профи nor SYNAPSE I СИНАПС shows ads.

### Which is updated more often, Справочник MSD профи or SYNAPSE I СИНАПС?

Справочник MSD профи ships an update every 7 months, and SYNAPSE I СИНАПС monthly. Most recently, Справочник MSD профи was updated on September 24, 2026 and SYNAPSE I СИНАПС on September 15, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*