# Manuale MSD Professionisti vs CTO SSM

The clearest difference is in-app purchases: Manuale MSD Professionisti at none against CTO SSM's 1. Manuale MSD Professionisti also leads on iOS requirement (13.0 vs 15.6). CTO SSM's advantage is update cadence (fortnightly vs every 6 months). On price, ads and device support there is nothing between them.

Both are free to download. CTO SSM sells 1 in-app purchase, starting at $24.99 per month. Manuale MSD Professionisti asks for nothing beyond the download.

Manuale MSD Professionisti ships an update every 6 months, CTO SSM fortnightly. The most recent releases landed on October 24, 2026 and October 30, 2026 respectively.

## The numbers

| Metric | Manuale MSD Professionisti | CTO SSM |
| --- | --- | --- |
| Price | Free | Free |
| Positive reviews | 84.0% of reviews | — |
| In-app purchases | **No** | Yes |
| Ads | No | No |
| Update frequency | Every 6 months | **Fortnightly** |
| Monetization | Free | — |
| Size | 188 MB | 38 MB |
| Requires iOS | **13.0** | 15.6 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [Merck Sharp & Dohme LLC](https://appshunter.io/developer/718617686) | [CTO Medicina](https://appshunter.io/developer/597003826) |

## What reviewers say

### Manuale MSD Professionisti

[App page](https://appshunter.io/ios/app/manuale-msd-professionisti/id1583953784)

This medical app provides healthcare professionals, nurses, and students with clear, practical explanations of thousands of conditions across all major medical and surgical specialties. It includes etiology, pathophysiology, prognosis, and treatment options, along with images, videos, and quizzes.

**Highlights:** Thousands of medical topics, Regularly updated by experts, Images and illustrations, Video tutorials for procedures, Medical quizzes, Medical news and commentary

**Features:** macOS Compatibility

**In-app purchases:** none


### CTO SSM

[App page](https://appshunter.io/ios/app/cto-ssm/id6743671817)

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Abbonamento mensile. | $24.99 | per month |


## Frequently asked questions

### Is Manuale MSD Professionisti free?

Manuale MSD Professionisti is free to download, with no in-app purchases.

### Is CTO SSM free?

CTO SSM is free to download, with in-app purchases available.

### Do Manuale MSD Professionisti or CTO SSM have ads?

Neither Manuale MSD Professionisti nor CTO SSM shows ads.

### Which is updated more often, Manuale MSD Professionisti or CTO SSM?

Manuale MSD Professionisti ships an update every 6 months, and CTO SSM fortnightly. Most recently, Manuale MSD Professionisti was updated on October 24, 2026 and CTO SSM on October 30, 2026.

---

*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*