# Know Your CML vs JOE in MDS

The clearest difference is update cadence: Know Your CML at monthly against JOE in MDS's every 18 months. Know Your CML also leads on iOS requirement (13.4 vs 15.0). On price, ads, in-app purchases and device support there is nothing between them.

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

Know Your CML ships an update monthly, JOE in MDS every 18 months. The most recent releases landed on October 12, 2026 and October 25, 2026 respectively.

## The numbers

| Metric | Know Your CML | JOE in MDS |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[5.0 (1 ratings)](https://appshunter.io/ios/app/know-your-cml/id1591499666/reviews)** | — |
| Number of ratings | **1** | — |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | **Monthly** | Every 18 months |
| Monetization | Free | — |
| Size | 59 MB | 17 MB |
| Requires iOS | **13.4** | 15.0 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 12+ | 17+ |
| Developer | [Leukemia Patient Advocates Foundation](https://appshunter.io/developer/1038000285) | [MDS Foundation, Inc](https://appshunter.io/developer/1355138228) |

## What reviewers say

### Know Your CML

[App page](https://appshunter.io/ios/app/know-your-cml/id1591499666)

This medical app helps patients and caregivers manage chronic myelogenous leukemia. It allows users to track side effects, compare test results, and access updated treatment guidelines and community news. Developed by patients for patients, it aims to support best practice sharing globally.

**Highlights:** Monitor side effects, Compare test results, Access treatment guidelines, View community news, Benchmarking data with other patients, Global patient organization network

**Features:** macOS Compatibility

**In-app purchases:** none


### JOE in MDS

[App page](https://appshunter.io/ios/app/joe-in-mds/id1659056497)

**Features:** macOS Compatibility

**In-app purchases:** none


## Frequently asked questions

### Is Know Your CML free?

Know Your CML is free to download, with no in-app purchases.

### Is JOE in MDS free?

JOE in MDS is free to download, with no in-app purchases.

### Do Know Your CML or JOE in MDS have ads?

Neither Know Your CML nor JOE in MDS shows ads.

### Which is updated more often, Know Your CML or JOE in MDS?

Know Your CML ships an update monthly, and JOE in MDS every 18 months. Most recently, Know Your CML was updated on October 12, 2026 and JOE in MDS on October 25, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*