# UpToDate Lexidrug vs APRN and PA’s Complete Guide

The clearest difference is review sentiment: UpToDate Lexidrug at 40% against APRN and PA’s Complete Guide's 0%. UpToDate Lexidrug also leads on ads (none vs shown) and ratings volume (6.1K vs 25). APRN and PA’s Complete Guide's advantage is monetization model (free with in-app purchases vs subscription) and iOS requirement (13.0 vs 16.0). On price, in-app purchases and device support there is nothing between them.

Both are free to download. UpToDate Lexidrug sells 2 in-app purchases, starting at $29.99 per month and APRN and PA’s Complete Guide sells 2 in-app purchases, starting at $39.99 per year. Whichever you choose, the download price is not the number that matters.

UpToDate Lexidrug holds the better App Store score, 4.7 against 4.5. That said, the two scores are not equally well evidenced: UpToDate Lexidrug has 6.1K ratings behind it against 25, so its average is the more settled of the two. Written reviews point the same way: 40% of UpToDate Lexidrug's written reviews are positive against 0% of APRN and PA’s Complete Guide's.

UpToDate Lexidrug ships an update every 2 months, APRN and PA’s Complete Guide every 8 months. The most recent releases landed on November 10, 2026 and November 3, 2026 respectively.

## The numbers

| Metric | UpToDate Lexidrug | APRN and PA’s Complete Guide |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[4.7 (6.1K ratings)](https://appshunter.io/ios/app/uptodate-lexidrug/id313401238/reviews)** | [4.5 (25 ratings)](https://appshunter.io/ios/app/aprn-and-pas-complete-guide/id1558030569/reviews) |
| Number of ratings | **6.1K** | 25 |
| Positive reviews | **39.8% of reviews** | 0.0% of reviews |
| In-app purchases | Yes | Yes |
| Ads | **No** | Yes |
| Update frequency | **Every 2 months** | Every 8 months |
| Monetization | Subscription | **Free with in-app purchases** |
| Best chart rank | **#20** | — |
| Size | 67 MB | 148 MB |
| Requires iOS | 16.0 | **13.0** |
| Devices | iPhone, iPad | **iPhone, iPad, iPod** |
| Age rating | 17+ | 17+ |
| Developer | [Lexi-Comp](https://appshunter.io/developer/295207927) | [Skyscape Medpresso Inc](https://appshunter.io/developer/818609416) |

## What reviewers say

### UpToDate Lexidrug

[App page](https://appshunter.io/ios/app/uptodate-lexidrug/id313401238)

**Currently charting:** #20 Top Grossing · Medical (US App Store)

This app provides comprehensive drug information and tools to aid in safe medication decisions. It offers daily updated clinical information, detailed drug databases, interaction checkers, and medical calculators. It is trusted by healthcare professionals and students for quick access to expert content.

**Highlights:** Daily updated clinical drug information, In-depth drug databases with dosing support, Comprehensive drug monographs, Hundreds of medical calculators, Interactive drug interactions checker, Offline database access

**Features:** Vision Pro support

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Lexicomp Professional Package | $29.99 | per month |
| Lexi-COMPLETE | $29.99 | per month |

**What reviewers like**

- 🌟 Best app for drug information
- 📚 Comprehensive and reliable content
- 🔍 Helpful search and navigation
- 🧮 Useful clinical tools (e.g., calculators)

**What reviewers complain about**

- 🐌 Sluggish performance and slow loading times
- 🔁 Frequent app crashes and freezes
- 🔒 Issues with login and subscription management
- 💰 Expensive subscription cost

**Reported bugs**

- App freezing when trying to access certain features
- Databases not downloading or updating properly
- Inconsistent behavior across iOS versions

**Requested features**

- Ability to customize database order and priority
- Improved offline functionality and background updates
- More user-friendly interface and navigation


### APRN and PA’s Complete Guide

[App page](https://appshunter.io/ios/app/aprn-and-pas-complete-guide/id1558030569)

This prescribing reference offers guidance on drug therapy for advanced healthcare providers and students. It includes over 600 diagnoses with detailed pharmacotherapy regimens, lab monitoring, and patient teaching points. Content is updated digitally and accessible offline.

**Highlights:** Over 600 diagnoses with pharmacotherapy regimens, Detailed drug information including dosing and FDA pregnancy category, Lab values to monitor and patient teaching points, Alphabetical diagnosis and drug cross-reference, Digital updates and offline access, SmartSearch technology for quick information retrieval

**Features:** macOS Compatibility

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| APRN & PA’s Complete Guide | $39.99 | per year |
| APRN & PA’s Complete Guide | $39.99 | one-time |


## Frequently asked questions

### Is UpToDate Lexidrug free?

UpToDate Lexidrug is free to download, with in-app purchases available.

### Is APRN and PA’s Complete Guide free?

APRN and PA’s Complete Guide is free to download, with in-app purchases available.

### Which has better reviews, UpToDate Lexidrug or APRN and PA’s Complete Guide?

UpToDate Lexidrug is rated higher. UpToDate Lexidrug averages 4.7 out of 5 from 6.1K ratings, while APRN and PA’s Complete Guide averages 4.5 from 25 ratings.

### Do UpToDate Lexidrug or APRN and PA’s Complete Guide have ads?

APRN and PA’s Complete Guide shows ads; UpToDate Lexidrug does not.

### Which is updated more often, UpToDate Lexidrug or APRN and PA’s Complete Guide?

UpToDate Lexidrug ships an update every 2 months, and APRN and PA’s Complete Guide every 8 months. Most recently, UpToDate Lexidrug was updated on November 10, 2026 and APRN and PA’s Complete Guide on November 3, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*