# UpToDate vs Drug Structures

The clearest difference is rating: Drug Structures at 4.7 against UpToDate's 3.6. Drug Structures also leads on monetization model (free vs subscription). UpToDate's advantage is update cadence (every 2 months vs every 14 months) and ratings volume (587 vs 3). On price, ads, in-app purchases and device support there is nothing between them.

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

Drug Structures holds the better App Store score, 4.7 against 3.6. That said, the two scores are not equally well evidenced: UpToDate has 587 ratings behind it against 3, so its average is the more settled of the two.

UpToDate ships an update every 2 months, Drug Structures every 14 months. The most recent releases landed on November 13, 2026 and November 2, 2026 respectively.

## The numbers

| Metric | UpToDate | Drug Structures |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [3.6 (587 ratings)](https://appshunter.io/ios/app/uptodate/id334265345/reviews) | **[4.7 (3 ratings)](https://appshunter.io/ios/app/drug-structures/id1207401347/reviews)** |
| Number of ratings | **587** | 3 |
| Positive reviews | 28.4% of reviews | — |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | **Every 2 months** | Every 14 months |
| Monetization | Subscription | **Free** |
| Size | 56 MB | 3 MB |
| Requires iOS | **18.0** | 18.6 |
| Devices | **iPhone, iPad** | iPhone |
| Age rating | 17+ | 12+ |
| Developer | [UpToDate, Inc.](https://appshunter.io/developer/334265348) | [David Bourne](https://appshunter.io/developer/1031086386) |

## What reviewers say

### UpToDate

[App page](https://appshunter.io/ios/app/uptodate/id334265345)

This clinical decision support tool provides healthcare professionals with evidence-based guidance to improve patient care. It features AI-powered conversational answers, continuously updated medical content, and tools for drug reference, calculations, and patient education.

**Highlights:** Expert AI conversational guidance, Gold standard clinical content, Practice-changing updates, Patient education materials, Drug reference and interactions, Clinical calculators, Kidney dosing guidance

**Features:** Vision Pro support

**In-app purchases:** none

**What reviewers like**

- 💎 Invaluable medical resource
- 🚀 Quick and easy to use
- 🔍 Comprehensive and up-to-date content

**What reviewers complain about**

- 🐛 Frequent crashes and freezing issues
- 🔌 Unreliable offline functionality
- 💰 Expensive subscription cost

**Reported bugs**

- Inability to download offline content
- Constant need to re-authenticate
- Incompatibility with recent iOS updates

**Requested features**

- Highlight and annotate content
- Improved institutional login support
- Dark mode and font size options


### Drug Structures

[App page](https://appshunter.io/ios/app/drug-structures/id1207401347)

This game helps pharmacy and healthcare students practice identifying drug structures. It offers a focused learning experience for medical professionals in training.

**Highlights:** Identify drug structures, Practice for healthcare students, Targeted medical education, Free to play

**Features:** macOS Compatibility

**In-app purchases:** none


## Frequently asked questions

### Is UpToDate free?

UpToDate is free to download, with no in-app purchases.

### Is Drug Structures free?

Drug Structures is free to download, with no in-app purchases.

### Which has better reviews, UpToDate or Drug Structures?

Drug Structures is rated higher. UpToDate averages 3.6 out of 5 from 587 ratings, while Drug Structures averages 4.7 from 3 ratings.

### Do UpToDate or Drug Structures have ads?

Neither UpToDate nor Drug Structures shows ads.

### Which is updated more often, UpToDate or Drug Structures?

UpToDate ships an update every 2 months, and Drug Structures every 14 months. Most recently, UpToDate was updated on November 13, 2026 and Drug Structures on November 2, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*