# CTC vs CTCAE 6 Pro

The clearest difference is price: CTCAE 6 Pro at Free against CTC's $3.99. CTCAE 6 Pro also leads on update cadence (monthly vs every 2 months) and iOS requirement (15.6 vs 17.6). On ads, in-app purchases and device support there is nothing between them.

CTCAE 6 Pro is free to download; CTC costs $3.99 up front. CTC sells 1 one-off in-app purchase and CTCAE 6 Pro sells 2 in-app purchases, starting at $1.99 per month. Whichever you choose, the download price is not the number that matters.

CTC ships an update every 2 months, CTCAE 6 Pro monthly. The most recent releases landed on September 13, 2026 and September 25, 2026 respectively.

## The numbers

| Metric | CTC | CTCAE 6 Pro |
| --- | --- | --- |
| Price | $3.99 | **Free** |
| Rating | — | **[5.0 (8 ratings)](https://appshunter.io/ios/app/ctcae-6-pro/id1625560237/reviews)** |
| Number of ratings | — | **8** |
| Positive reviews | 55.6% of reviews | — |
| In-app purchases | Yes | Yes |
| Ads | No | No |
| Update frequency | Every 2 months | **Monthly** |
| Monetization | Paid | **Freemium** |
| Size | 2 MB | 87 MB |
| Requires iOS | 17.6 | **15.6** |
| Devices | iPhone, iPad, Mac | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [Arpacore B.V.](https://appshunter.io/developer/1441928570) | [Koichiro Watanabe](https://appshunter.io/developer/1077985400) |

## What reviewers say

### CTC

[App page](https://appshunter.io/ios/app/ctc-ae-plus/id349258523)

This medical reference app provides quick access to standardized adverse event criteria and grading scales for oncology research. It allows for efficient logging, tracking, and reporting of patient events, including performance scores and custom entries. Data is kept strictly on-device for privacy and compliance.

**Highlights:** CTCAE v4 and v5 reference, Performance score integration (Karnofsky, ECOG, Lansky), Advanced adverse event logger, Custom event creation, CSV data import/export, On-device data storage

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Adverse Event Logger | $3.99 | one-time |


### CTCAE 6 Pro

[App page](https://appshunter.io/ios/app/ctcae-6-pro/id1625560237)

Easily review and annotate medical toxicity criteria. Bookmark adverse events, search keywords, and organize entries chronologically. Offers local data storage and optional premium features for advanced note-taking and data export.

**Highlights:** Quick CTCAE 6.0 content access, Unlimited adverse event bookmarking, Keyword search with highlighting, Local data storage, Version comparison (5.0 ⇄ 6.0), Smart notes and timeline management, Spreadsheet to custom list app conversion

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Premium Plan – Monthly | $1.99 | per month |
| Premium Plan – Annual | $9.99 | per year |


## Frequently asked questions

### Is CTC free?

CTC costs $3.99, and also offers in-app purchases.

### Is CTCAE 6 Pro free?

CTCAE 6 Pro is free to download, with in-app purchases available.

### Do CTC or CTCAE 6 Pro have ads?

Neither CTC nor CTCAE 6 Pro shows ads.

### Which is updated more often, CTC or CTCAE 6 Pro?

CTC ships an update every 2 months, and CTCAE 6 Pro monthly. Most recently, CTC was updated on September 13, 2026 and CTCAE 6 Pro on September 25, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*