# CTC vs CTCAE 5 Pro

The clearest difference is review sentiment: CTC at 56% against CTCAE 5 Pro's 0%. CTCAE 5 Pro's advantage is price (Free vs $3.99) and iOS requirement (15.5 vs 17.6). On update cadence, ads, in-app purchases and device support there is nothing between them.

CTCAE 5 Pro is free to download; CTC costs $3.99 up front. CTC sells 1 one-off in-app purchase and CTCAE 5 Pro sells 2 in-app purchases, starting at $1.99 per month. Whichever you choose, the download price is not the number that matters.

CTC ships an update every 2 months, CTCAE 5 Pro every 5 weeks. The most recent releases landed on September 13, 2026 and September 22, 2026 respectively.

## The numbers

| Metric | CTC | CTCAE 5 Pro |
| --- | --- | --- |
| Price | $3.99 | **Free** |
| Rating | — | **[4.8 (38 ratings)](https://appshunter.io/ios/app/ctcae-5-pro/id1625569535/reviews)** |
| Number of ratings | — | **38** |
| Positive reviews | **55.6% of reviews** | 0.0% of reviews |
| In-app purchases | Yes | Yes |
| Ads | No | No |
| Update frequency | Every 2 months | **Every 5 weeks** |
| Monetization | Paid | **Freemium** |
| Size | 2 MB | 60 MB |
| Requires iOS | 17.6 | **15.5** |
| Devices | iPhone, iPad, Mac | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [Arpacore B.V.](https://appshunter.io/developer/1441928570) | [Koichiro Watanabe](https://appshunter.io/developer/1077985400) |

## What reviewers say

### CTC

[App page](https://appshunter.io/ios/app/ctc-ae-plus/id349258523)

This medical reference app provides quick access to standardized adverse event criteria and grading scales for oncology research. It allows for efficient logging, tracking, and reporting of patient events, including performance scores and custom entries. Data is kept strictly on-device for privacy and compliance.

**Highlights:** CTCAE v4 and v5 reference, Performance score integration (Karnofsky, ECOG, Lansky), Advanced adverse event logger, Custom event creation, CSV data import/export, On-device data storage

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Adverse Event Logger | $3.99 | one-time |


### CTCAE 5 Pro

[App page](https://appshunter.io/ios/app/ctcae-5-pro/id1625569535)

This app helps review and take notes on CTCAE documents. It offers local data storage for privacy and premium features like version comparison and advanced note-taking with a subscription.

**Highlights:** Streamlined CTCAE Document Access, Local data storage for enhanced privacy, Version comparison tool, Advanced chronological note-taking with hashtags, Custom app creation from spreadsheets, Flexible backup and archiving (XLSX, CSV)

**Features:** macOS Compatibility, Family Sharing, Vision Pro support

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Monthly subscription | $1.99 | per month |
| Annual subscription | $9.99 | per year |


## Frequently asked questions

### Is CTC free?

CTC costs $3.99, and also offers in-app purchases.

### Is CTCAE 5 Pro free?

CTCAE 5 Pro is free to download, with in-app purchases available.

### Do CTC or CTCAE 5 Pro have ads?

Neither CTC nor CTCAE 5 Pro shows ads.

### Which is updated more often, CTC or CTCAE 5 Pro?

CTC ships an update every 2 months, and CTCAE 5 Pro every 5 weeks. Most recently, CTC was updated on September 13, 2026 and CTCAE 5 Pro on September 22, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*