# Medicine Central vs APRN and PA’s Complete Guide

The clearest difference is review sentiment: Medicine Central at 69% against APRN and PA’s Complete Guide's 0%. Medicine Central also leads on ads (none vs shown) and rating (5.0 vs 4.5). APRN and PA’s Complete Guide's advantage is iOS requirement (13.0 vs 15.0). On price, update cadence, in-app purchases and monetization model there is nothing between them.

Both are free to download. Medicine Central sells 2 in-app purchases, starting at $99.99 per year and APRN and PA’s Complete Guide sells 2 in-app purchases, starting at $39.99 per year. Whichever you choose, the download price is not the number that matters.

Medicine Central holds the better App Store score, 5.0 against 4.5. Both are backed by a comparable volume of ratings — 118 and 25 respectively. Written reviews point the same way: 69% of Medicine Central's written reviews are positive against 0% of APRN and PA’s Complete Guide's.

Medicine Central ships an update every 6 months, APRN and PA’s Complete Guide every 8 months. The most recent releases landed on November 1, 2026 and November 3, 2026 respectively.

## The numbers

| Metric | Medicine Central | APRN and PA’s Complete Guide |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[5.0 (118 ratings)](https://appshunter.io/ios/app/medicine-central/id350347587/reviews)** | [4.5 (25 ratings)](https://appshunter.io/ios/app/aprn-and-pas-complete-guide/id1558030569/reviews) |
| Number of ratings | **118** | 25 |
| Positive reviews | **69.2% of reviews** | 0.0% of reviews |
| In-app purchases | Yes | Yes |
| Ads | **No** | Yes |
| Update frequency | **Every 6 months** | Every 8 months |
| Monetization | Free with in-app purchases | Free with in-app purchases |
| Size | 9 MB | 148 MB |
| Requires iOS | 15.0 | **13.0** |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [Unbound Medicine, Inc.](https://appshunter.io/developer/300420400) | [Skyscape Medpresso Inc](https://appshunter.io/developer/818609416) |

## What reviewers say

### Medicine Central

[App page](https://appshunter.io/ios/app/medicine-central/id350347587)

This comprehensive medical reference app provides quick access to essential information on diagnoses, treatments, and drug details. It integrates multiple trusted resources, including clinical consults, drug guides, diagnostic tests, and PubMed access, for efficient point-of-care decision-making.

**Highlights:** Over 1,000 medical conditions with treatment recommendations, Comprehensive drug information for over 5,000 drugs, Differential diagnoses search by symptom or disease, Information on over 450 common laboratory tests, Full PubMed database search with visual exploration, Cross-linking between integrated resources, Full text search across all references

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Medicine Central Renewal | $99.99 | per year |
| Medicine Central | $169.99 | one-time |


### APRN and PA’s Complete Guide

[App page](https://appshunter.io/ios/app/aprn-and-pas-complete-guide/id1558030569)

This prescribing reference offers guidance on drug therapy for advanced healthcare providers and students. It includes over 600 diagnoses with detailed pharmacotherapy regimens, lab monitoring, and patient teaching points. Content is updated digitally and accessible offline.

**Highlights:** Over 600 diagnoses with pharmacotherapy regimens, Detailed drug information including dosing and FDA pregnancy category, Lab values to monitor and patient teaching points, Alphabetical diagnosis and drug cross-reference, Digital updates and offline access, SmartSearch technology for quick information retrieval

**Features:** macOS Compatibility

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| APRN & PA’s Complete Guide | $39.99 | per year |
| APRN & PA’s Complete Guide | $39.99 | one-time |


## Frequently asked questions

### Is Medicine Central free?

Medicine Central is free to download, with in-app purchases available.

### Is APRN and PA’s Complete Guide free?

APRN and PA’s Complete Guide is free to download, with in-app purchases available.

### Which has better reviews, Medicine Central or APRN and PA’s Complete Guide?

Medicine Central is rated higher. Medicine Central averages 5.0 out of 5 from 118 ratings, while APRN and PA’s Complete Guide averages 4.5 from 25 ratings.

### Do Medicine Central or APRN and PA’s Complete Guide have ads?

APRN and PA’s Complete Guide shows ads; Medicine Central does not.

### Which is updated more often, Medicine Central or APRN and PA’s Complete Guide?

Medicine Central ships an update every 6 months, and APRN and PA’s Complete Guide every 8 months. Most recently, Medicine Central was updated on November 1, 2026 and APRN and PA’s Complete Guide on November 3, 2026.

---

*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*