# CTCAE v4.0 vs ASTCT Practice Guidelines

The clearest difference is review sentiment: ASTCT Practice Guidelines at 100% against CTCAE v4.0's 17%. ASTCT Practice Guidelines also leads on rating (5.0 vs 3.5) and update cadence (every 2 months vs every 44 months). CTCAE v4.0's advantage is iOS requirement (9.2 vs 15.0). On price, ratings volume, ads and in-app purchases there is nothing between them.

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

ASTCT Practice Guidelines holds the better App Store score, 5.0 against 3.5. Both are backed by a comparable volume of ratings — 11 and 4 respectively. Written reviews point the same way: 17% of CTCAE v4.0's written reviews are positive against 100% of ASTCT Practice Guidelines's.

CTCAE v4.0 ships an update every 44 months, ASTCT Practice Guidelines every 2 months. The most recent releases landed on September 24, 2026 and October 13, 2026 respectively.

## The numbers

| Metric | CTCAE v4.0 | ASTCT Practice Guidelines |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [3.5 (11 ratings)](https://appshunter.io/ios/app/ctcae-v40/id378487242/reviews) | **[5.0 (4 ratings)](https://appshunter.io/ios/app/astct-practice-guidelines/id1204871675/reviews)** |
| Number of ratings | **11** | 4 |
| Positive reviews | 16.7% of reviews | **100.0% of reviews** |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | Every 44 months | **Every 2 months** |
| Monetization | Free | Free |
| Size | 3 MB | 107 MB |
| Requires iOS | **9.2** | 15.0 |
| Devices | iPhone, iPod | **iPhone, iPad, iPod** |
| Age rating | 12+ | 17+ |
| Developer | [The Children's Hospital of Philadelphia](https://appshunter.io/developer/351401975) | [ASBMT](https://appshunter.io/developer/1204871674) |

## What reviewers say

### CTCAE v4.0

[App page](https://appshunter.io/ios/app/ctcae-v40/id378487242)

This medical reference app provides a standardized system for grading the severity of adverse events related to drug treatments or medical devices. It offers hierarchical navigation, bookmarking, and search functionality for quick access to definitions and grading standards.

**Highlights:** Standardized adverse event grading system, Definitions for event severity (grades 1-5), Hierarchical navigation of categories, Bookmark frequently used events, Search across names, definitions, and grades

**Features:** macOS Compatibility

**In-app purchases:** none


### ASTCT Practice Guidelines

[App page](https://appshunter.io/ios/app/astct-practice-guidelines/id1204871675)

Access up-to-date practice guidelines, evidence-based reviews, and clinical calculators for blood, bone marrow transplantation, and cellular therapies. Developed by experts, this app aids clinical decision-making with immediate access to crucial information.

**Highlights:** Practice guidelines, Evidence-based reviews, Clinical calculators, HCT patient tools, Expert-developed content, Detailed references

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


## Frequently asked questions

### Is CTCAE v4.0 free?

CTCAE v4.0 is free to download, with no in-app purchases.

### Is ASTCT Practice Guidelines free?

ASTCT Practice Guidelines is free to download, with no in-app purchases.

### Which has better reviews, CTCAE v4.0 or ASTCT Practice Guidelines?

ASTCT Practice Guidelines is rated higher. CTCAE v4.0 averages 3.5 out of 5 from 11 ratings, while ASTCT Practice Guidelines averages 5.0 from 4 ratings.

### Do CTCAE v4.0 or ASTCT Practice Guidelines have ads?

Neither CTCAE v4.0 nor ASTCT Practice Guidelines shows ads.

### Which is updated more often, CTCAE v4.0 or ASTCT Practice Guidelines?

CTCAE v4.0 ships an update every 44 months, and ASTCT Practice Guidelines every 2 months. Most recently, CTCAE v4.0 was updated on September 24, 2026 and ASTCT Practice Guidelines on October 13, 2026.

---

*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*