# CTCAE v4.0 vs ASCO Guidelines

The clearest difference is rating: ASCO Guidelines at 4.8 against CTCAE v4.0's 3.5. ASCO Guidelines also leads on review sentiment (57% vs 17%) and update cadence (every 5 months vs every 44 months). On price, ads, in-app purchases and monetization model there is nothing between them.

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

ASCO Guidelines holds the better App Store score, 4.8 against 3.5. That said, the two scores are not equally well evidenced: ASCO Guidelines has 257 ratings behind it against 11, so its average is the more settled of the two. Written reviews point the same way: 17% of CTCAE v4.0's written reviews are positive against 57% of ASCO Guidelines's.

CTCAE v4.0 ships an update every 44 months, ASCO Guidelines every 5 months. The most recent releases landed on October 10, 2026 and October 16, 2026 respectively.

## The numbers

| Metric | CTCAE v4.0 | ASCO Guidelines |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [3.5 (11 ratings)](https://appshunter.io/ios/app/ctcae-v40/id378487242/reviews) | **[4.8 (257 ratings)](https://appshunter.io/ios/app/asco-guidelines/id1238827183/reviews)** |
| Number of ratings | 11 | **257** |
| Positive reviews | 16.7% of reviews | **57.1% of reviews** |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | Every 44 months | **Every 5 months** |
| Monetization | Free | Free |
| Size | 3 MB | 411 MB |
| Requires iOS | **9.2** | 10.0 |
| Devices | iPhone, iPod | **iPhone, iPad, iPod** |
| Age rating | 12+ | 12+ |
| Developer | [The Children's Hospital of Philadelphia](https://appshunter.io/developer/351401975) | [American Society of Clinical Oncology](https://appshunter.io/developer/1513043539) |

## What reviewers say

### CTCAE v4.0

[App page](https://appshunter.io/ios/app/ctcae-v40/id378487242)

This medical reference app provides a standardized system for grading the severity of adverse events related to drug treatments or medical devices. It offers hierarchical navigation, bookmarking, and search functionality for quick access to definitions and grading standards.

**Highlights:** Standardized adverse event grading system, Definitions for event severity (grades 1-5), Hierarchical navigation of categories, Bookmark frequently used events, Search across names, definitions, and grades

**Features:** macOS Compatibility

**In-app purchases:** none


### ASCO Guidelines

[App page](https://appshunter.io/ios/app/asco-guidelines/id1238827183)

Access comprehensive cancer care guidelines and interactive tools to inform treatment decisions. This app supports healthcare providers, patients, and caregivers in implementing recommended cancer care options for various cancer types, aiming to improve the quality of care.

**Highlights:** Guideline recommendations for cancer care, Interactive treatment decision tools, Supports healthcare providers, Informs patients and caregivers, Covers various cancer types, Regularly updated content

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


## Frequently asked questions

### Is CTCAE v4.0 free?

CTCAE v4.0 is free to download, with no in-app purchases.

### Is ASCO Guidelines free?

ASCO Guidelines is free to download, with no in-app purchases.

### Which has better reviews, CTCAE v4.0 or ASCO Guidelines?

ASCO Guidelines is rated higher. CTCAE v4.0 averages 3.5 out of 5 from 11 ratings, while ASCO Guidelines averages 4.8 from 257 ratings.

### Do CTCAE v4.0 or ASCO Guidelines have ads?

Neither CTCAE v4.0 nor ASCO Guidelines shows ads.

### Which is updated more often, CTCAE v4.0 or ASCO Guidelines?

CTCAE v4.0 ships an update every 44 months, and ASCO Guidelines every 5 months. Most recently, CTCAE v4.0 was updated on October 10, 2026 and ASCO Guidelines on October 16, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*