# Case Files vs MRTLE2 Study

The clearest difference is in-app purchases: MRTLE2 Study at none against Case Files's 6. MRTLE2 Study also leads on update cadence (every 5 weeks vs every 19 months) and iOS requirement (13.0 vs 15.6). On price, ads and device support there is nothing between them.

Both are free to download. Case Files sells 6 in-app purchases, starting at $6.99 per 7 days. MRTLE2 Study asks for nothing beyond the download.

Case Files ships an update every 19 months, MRTLE2 Study every 5 weeks. The most recent releases landed on November 3, 2026 and November 6, 2026 respectively.

## The numbers

| Metric | Case Files | MRTLE2 Study |
| --- | --- | --- |
| Price | Free | Free |
| Positive reviews | 70.6% of reviews | — |
| In-app purchases | Yes | **No** |
| Ads | No | No |
| Update frequency | Every 19 months | **Every 5 weeks** |
| Monetization | Free with in-app purchases | — |
| Size | 28 MB | 9 MB |
| Requires iOS | 15.6 | **13.0** |
| Devices | **iPhone, iPad, iPod** | iPhone, iPod |
| Age rating | 12+ | 17+ |
| Developer | [Expanded Apps](https://appshunter.io/developer/313709778) | [Irody Inc.](https://appshunter.io/developer/362460645) |

## What reviewers say

### Case Files

[App page](https://appshunter.io/ios/app/case-files-physiology/id464681219)

This app helps medical students learn and review physiology by presenting 51 high-yield clinical cases. It reinforces the connection between basic science and clinical medicine, improving diagnostic skills and exam performance. A free sample case is included, with more available via subscription.

**Highlights:** 51 high-yield clinical cases, USMLE-style questions, Interactive learning system, Study, Exam, and Bookmark modes, Progress tracking, Notes section per case, iCloud support

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (6)**

| Purchase | Price | Billing |
| --- | --- | --- |
| 1 Week | $6.99 | per 7 days |
| Weekly Access | $11.99 | per 7 days |
| 1 Month | $18.99 | per month |
| Monthly Access | $19.99 | per month |
| 1 Year | $59.99 | per year |
| Lifetime Access | $39.99 | one-time |


### MRTLE2 Study

[App page](https://appshunter.io/ios/app/mrtle2-study/id1451800482)

**Features:** macOS Compatibility

**In-app purchases:** none


## Frequently asked questions

### Is Case Files free?

Case Files is free to download, with in-app purchases available.

### Is MRTLE2 Study free?

MRTLE2 Study is free to download, with no in-app purchases.

### Do Case Files or MRTLE2 Study have ads?

Neither Case Files nor MRTLE2 Study shows ads.

### Which is updated more often, Case Files or MRTLE2 Study?

Case Files ships an update every 19 months, and MRTLE2 Study every 5 weeks. Most recently, Case Files was updated on November 3, 2026 and MRTLE2 Study on November 6, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*