# ApoThera vs Mosby's Drug Reference

The clearest difference is review sentiment: ApoThera at 89% against Mosby's Drug Reference's 32%. ApoThera also leads on update cadence (every 2 months vs every 9 months) and iOS requirement (11.0 vs 15.0). Mosby's Drug Reference's advantage is ads (none vs shown) and rating (4.6 vs 4.2). On price, in-app purchases, monetization model and device support there is nothing between them.

Both are free to download. ApoThera sells 2 in-app purchases, starting at $2.99 per month and Mosby's Drug Reference sells 1 in-app purchase, starting at $45.99 per year. Whichever you choose, the download price is not the number that matters.

Mosby's Drug Reference holds the better App Store score, 4.6 against 4.2. That said, the two scores are not equally well evidenced: Mosby's Drug Reference has 235 ratings behind it against 14, so its average is the more settled of the two. Written reviews complicate that: 89% of ApoThera's written reviews are positive against 32% of Mosby's Drug Reference's, so the app with the better star average is not the one people write more warmly about.

ApoThera ships an update every 2 months, Mosby's Drug Reference every 9 months. The most recent releases landed on October 8, 2026 and October 15, 2026 respectively.

## The numbers

| Metric | ApoThera | Mosby's Drug Reference |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [4.2 (14 ratings)](https://appshunter.io/ios/app/apothera/id526613282/reviews) | **[4.6 (235 ratings)](https://appshunter.io/ios/app/mosbys-drug-reference/id959042883/reviews)** |
| Number of ratings | 14 | **235** |
| Positive reviews | **88.9% of reviews** | 31.8% of reviews |
| In-app purchases | Yes | Yes |
| Ads | Yes | **No** |
| Update frequency | **Every 2 months** | Every 9 months |
| Monetization | Free with in-app purchases | Free with in-app purchases |
| Best chart rank | — | **#200** |
| Size | 19 MB | 9 MB |
| Requires iOS | **11.0** | 15.0 |
| Devices | iPhone, iPad, iPod | **iPhone, iPad, iPod, Mac** |
| Age rating | 17+ | 17+ |
| Developer | [Apothera Inc.](https://appshunter.io/developer/526613285) | [Unbound Medicine, Inc.](https://appshunter.io/developer/300420400) |

## What reviewers say

### ApoThera

[App page](https://appshunter.io/ios/app/apothera/id526613282)

This app provides clinical decision support for healthcare professionals. It offers treatment recommendations, disease management tools, drug information, interaction checkers, medical calculators, and patient savings programs. Content is updated daily and covers a wide range of medical specialties.

**Highlights:** Clinical guidelines and treatment recommendations, Disease management and drug information, Drug interaction checker, Medical calculators and conversion tools, Patient Rx savings and discounts, PDF document archiving

**Features:** macOS Compatibility

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| ApoThera Monthly | $2.99 | per month |
| ApoThera 1 year Auto-Renew | $59.99 | per year |


### Mosby's Drug Reference

[App page](https://appshunter.io/ios/app/mosbys-drug-reference/id959042883)

**Currently charting:** #200 Top Grossing · Medical (US App Store)

This app provides healthcare professionals with comprehensive drug information, including actions, usage, dosage, interactions, and side effects. It emphasizes patient safety with Black Box Warnings, Safety Alerts, and information on life-threatening side effects. Features include custom notes, highlights, and quick search functionality.

**Highlights:** Over 5,000 drug listings, Black Box Warnings and Safety Alerts, Drug action, usage, dosage, interactions, side effects, Custom notes and highlights, Full text search, Appendix of recent FDA-approvals

**Features:** Vision Pro support

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Mosby's Drug Reference | $45.99 | per year |


## Frequently asked questions

### Is ApoThera free?

ApoThera is free to download, with in-app purchases available.

### Is Mosby's Drug Reference free?

Mosby's Drug Reference is free to download, with in-app purchases available.

### Which has better reviews, ApoThera or Mosby's Drug Reference?

Mosby's Drug Reference is rated higher. ApoThera averages 4.2 out of 5 from 14 ratings, while Mosby's Drug Reference averages 4.6 from 235 ratings.

### Do ApoThera or Mosby's Drug Reference have ads?

ApoThera shows ads; Mosby's Drug Reference does not.

### Which is updated more often, ApoThera or Mosby's Drug Reference?

ApoThera ships an update every 2 months, and Mosby's Drug Reference every 9 months. Most recently, ApoThera was updated on October 8, 2026 and Mosby's Drug Reference on October 15, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*