# GuiaUPP vs Manual MSD versión pro

The clearest difference is update cadence: GuiaUPP at every 3 weeks against Manual MSD versión pro's every 5 months. GuiaUPP also leads on iOS requirement (8.0 vs 13.0). On price, ads, in-app purchases and device support there is nothing between them.

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

GuiaUPP ships an update every 3 weeks, Manual MSD versión pro every 5 months. The most recent releases landed on October 26, 2026 and October 24, 2026 respectively.

## The numbers

| Metric | GuiaUPP | Manual MSD versión pro |
| --- | --- | --- |
| Price | Free | Free |
| Rating | — | **[4.9 (141 ratings)](https://appshunter.io/ios/app/manual-msd-version-pro/id1151854781/reviews)** |
| Number of ratings | — | **141** |
| Positive reviews | — | 93.7% of reviews |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | **Every 3 weeks** | Every 5 months |
| Monetization | — | Free |
| Size | 21 MB | 186 MB |
| Requires iOS | **8.0** | 13.0 |
| Devices | iPhone, iPod | **iPhone, iPad, iPod** |
| Age rating | 17+ | +17 |
| Developer | [ERTAKY](https://appshunter.io/developer/530321340) | [Merck Sharp & Dohme LLC](https://appshunter.io/developer/718617686) |

## What reviewers say

### GuiaUPP

[App page](https://appshunter.io/ios/app/guiaupp/id546315186)

**Features:** macOS Compatibility

**In-app purchases:** none


### Manual MSD versión pro

[App page](https://appshunter.io/ios/app/manual-msd-version-pro/id1151854781)

This app provides medical professionals with clear, practical explanations on thousands of conditions across major medical and surgical specialties. It covers etiology, pathophysiology, prognosis, and treatment options, featuring regular updates from over 350 academic physicians.

**Highlights:** Thousands of medical topics, Regularly updated by physicians, Photos and illustrations, Instructional videos, Quizzes and medical news, Expert editorials

**Features:** macOS Compatibility

**In-app purchases:** none


## Frequently asked questions

### Is GuiaUPP free?

GuiaUPP is free to download, with no in-app purchases.

### Is Manual MSD versión pro free?

Manual MSD versión pro is free to download, with no in-app purchases.

### Do GuiaUPP or Manual MSD versión pro have ads?

Neither GuiaUPP nor Manual MSD versión pro shows ads.

### Which is updated more often, GuiaUPP or Manual MSD versión pro?

GuiaUPP ships an update every 3 weeks, and Manual MSD versión pro every 5 months. Most recently, GuiaUPP was updated on October 26, 2026 and Manual MSD versión pro on October 24, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*