# NephroCalc™ vs Sanford Guide Antimicrobial

The clearest difference is price: Sanford Guide Antimicrobial at Free against NephroCalc™'s $3.99. Sanford Guide Antimicrobial also leads on update cadence (every 2 weeks vs every 10 months) and ratings volume (1.9K vs 1). NephroCalc™'s advantage is in-app purchases (none vs 3) and rating (5.0 vs 4.8). On ads and device support there is nothing between them.

Sanford Guide Antimicrobial is free to download; NephroCalc™ costs $3.99 up front. Sanford Guide Antimicrobial sells 3 in-app purchases, starting at $4.99 per year. NephroCalc™ asks for nothing beyond the download.

NephroCalc™ holds the better App Store score, 5.0 against 4.8. That said, the two scores are not equally well evidenced: Sanford Guide Antimicrobial has 1.9K ratings behind it against 1, so its average is the more settled of the two.

NephroCalc™ ships an update every 10 months, Sanford Guide Antimicrobial every 2 weeks. Both last shipped on November 1, 2026.

## The numbers

| Metric | NephroCalc™ | Sanford Guide Antimicrobial |
| --- | --- | --- |
| Price | $3.99 | **Free** |
| Rating | **[5.0 (1 ratings)](https://appshunter.io/ios/app/nephrocalc/id573215712/reviews)** | [4.8 (1.9K ratings)](https://appshunter.io/ios/app/sanford-guide-antimicrobial/id863196620/reviews) |
| Number of ratings | 1 | **1.9K** |
| Positive reviews | — | 88.4% of reviews |
| In-app purchases | **No** | Yes |
| Ads | No | No |
| Update frequency | Every 10 months | **Every 2 weeks** |
| Monetization | **Paid** | Subscription |
| Best chart rank | #144 | **#5** |
| Size | 24 MB | 46 MB |
| Requires iOS | **13.0** | 15.0 |
| Devices | iPhone, iPod | **iPhone, iPad, iPod** |
| Age rating | 17+ | 17+ |
| Developer | [ScyMed, Inc](https://appshunter.io/developer/545140733) | [Antimicrobial Therapy, Inc.](https://appshunter.io/developer/443442554) |

## What reviewers say

### NephroCalc™

[App page](https://appshunter.io/ios/app/nephrocalc/id573215712)

**Currently charting:** #144 Top Paid · Medical (US App Store)

This medical calculator app provides over 100 essential formulas and equations for assessing patients with kidney disease and acid-base disorders. It features innovative Master panels for combined calculations and a physician-friendly interface for efficient patient data management.

**Highlights:** Over 100 renal and acid-base equations, Innovative MultiCalx™ Master panels, Customizable mCalx™ DARK calculator, Physician-friendly intuitive interface, Automatic unit conversion, Color-coded normal-abnormal outputs, Fully referenced clinical data

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


### Sanford Guide Antimicrobial

[App page](https://appshunter.io/ios/app/sanford-guide-antimicrobial/id863196620)

**Currently charting:** #5 Top Grossing · Medical (US App Store)

Provides clinicians with concise, evidence-based answers for infectious disease treatment decisions. Features interactive tools like spectra charts and calculators, updated frequently by an expert editorial team.

**Highlights:** Clinically actionable answers, Institutionally diverse editorial team, Constant updates, Interactive antibacterial spectra chart, Drug-drug interaction checker, Trustworthy calculators for dosing

**Features:** Vision Pro support

**In-app purchases (3)**

| Purchase | Price | Billing |
| --- | --- | --- |
| U.S. Vaccine Guidelines | $4.99 | per year |
| Sanford Guide | $39.99 | per year |
| Sanford Guide All Access | $79.99 | per year |

**What reviewers like**

- 👍 Easy to use
- 🚀 Quick access to information
- 💡 Helpful charts and tables
- 🔍 Comprehensive coverage of infections and treatments
- 📚 Up-to-date content and frequent updates

**What reviewers complain about**

- 🐛 Occasional crashes or freezing
- ⏱️ Slow search function
- 💰 Expensive subscription model
- 🔒 Login issues and subscription verification problems

**Reported bugs**

- App freezing or closing unexpectedly
- Login and subscription verification problems
- Corrupted passwords and inability to reset

**Requested features**

- Side-by-side antibiotic susceptibility comparison
- Offline access to content
- Improved navigation and UI


## Frequently asked questions

### Is NephroCalc™ free?

NephroCalc™ costs $3.99, with no in-app purchases.

### Is Sanford Guide Antimicrobial free?

Sanford Guide Antimicrobial is free to download, with in-app purchases available.

### Which has better reviews, NephroCalc™ or Sanford Guide Antimicrobial?

NephroCalc™ is rated higher. NephroCalc™ averages 5.0 out of 5 from 1 ratings, while Sanford Guide Antimicrobial averages 4.8 from 1.9K ratings.

### Do NephroCalc™ or Sanford Guide Antimicrobial have ads?

Neither NephroCalc™ nor Sanford Guide Antimicrobial shows ads.

### Which is updated more often, NephroCalc™ or Sanford Guide Antimicrobial?

NephroCalc™ ships an update every 10 months, and Sanford Guide Antimicrobial every 2 weeks. Most recently, NephroCalc™ was updated on November 1, 2026 and Sanford Guide Antimicrobial on November 1, 2026.

### Which is more popular, NephroCalc™ or Sanford Guide Antimicrobial?

NephroCalc™ currently peaks at #144 in the App Store charts, and Sanford Guide Antimicrobial at #5. Chart position reflects recent download velocity rather than total install base.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*