# n4Studies Plus vs MSD E

The clearest difference is price: MSD E at Free against n4Studies Plus's $7.99. MSD E also leads on iOS requirement (11.0 vs 16.0). On update cadence, ads, in-app purchases and device support there is nothing between them.

MSD E is free to download; n4Studies Plus costs $7.99 up front. Neither carries in-app purchases, so what you see is what you pay.

n4Studies Plus ships an update every 2 months, MSD E every 5 weeks. The most recent releases landed on September 15, 2026 and February 20, 2026 respectively.

## The numbers

| Metric | n4Studies Plus | MSD E |
| --- | --- | --- |
| Price | $7.99 | **Free** |
| Rating | **[3.0 (1 ratings)](https://appshunter.io/ios/app/n4studies-plus/id6450650727/reviews)** | — |
| Number of ratings | **1** | — |
| Positive reviews | 0.0% of reviews | — |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | Every 2 months | **Every 5 weeks** |
| Monetization | Paid | — |
| Size | 16 MB | 45 MB |
| Requires iOS | 16.0 | **11.0** |
| Devices | iPhone | **iPhone, iPod** |
| Age rating | 4+ | 17+ |
| Developer | [Chetta Ngamjarus](https://appshunter.io/developer/680516904) | [Deverhood HT Co.,Ltd.](https://appshunter.io/developer/1785579550) |

## What reviewers say

### n4Studies Plus

[App page](https://appshunter.io/ios/app/n4studies-plus/id6450650727)

This app simplifies sample size and study power calculations for various research designs. It offers tools for regression, survival analysis, diagnostic studies, and more, helping users find calculations in minutes.

**Highlights:** Sample size calculation for regression, Sample size for survival analysis, Sample size for diagnostic and cross-over studies, Sample size for population means and proportions, Sample size for case-control and cohort studies, Study power calculations, Email output sharing

**Features:** macOS Compatibility

**In-app purchases:** none


### MSD E

[App page](https://appshunter.io/ios/app/msd-e/id6502573447)

**Features:** macOS Compatibility

**In-app purchases:** none


## Frequently asked questions

### Is n4Studies Plus free?

n4Studies Plus costs $7.99, with no in-app purchases.

### Is MSD E free?

MSD E is free to download, with no in-app purchases.

### Do n4Studies Plus or MSD E have ads?

Neither n4Studies Plus nor MSD E shows ads.

### Which is updated more often, n4Studies Plus or MSD E?

n4Studies Plus ships an update every 2 months, and MSD E every 5 weeks. Most recently, n4Studies Plus was updated on September 15, 2026 and MSD E on February 20, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*