# INFORMUS vs ReplyMD

The clearest difference is rating: ReplyMD at 5.0 against INFORMUS's 4.3. ReplyMD also leads on update cadence (every 10 days vs monthly). On price, ratings volume, ads and in-app purchases there is nothing between them.

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

ReplyMD holds the better App Store score, 5.0 against 4.3. Both are backed by a comparable volume of ratings — 8 and 4 respectively.

INFORMUS ships an update monthly, ReplyMD every 10 days. The most recent releases landed on October 7, 2026 and October 5, 2026 respectively.

## The numbers

| Metric | INFORMUS | ReplyMD |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [4.3 (8 ratings)](https://appshunter.io/ios/app/informus/id6471454872/reviews) | **[5.0 (4 ratings)](https://appshunter.io/ios/app/replymd/id6741511114/reviews)** |
| Number of ratings | **8** | 4 |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | Monthly | **Every 10 days** |
| Monetization | Free | Free |
| Size | 46 MB | 66 MB |
| Requires iOS | 15.1 | 15.1 |
| Devices | iPhone, iPod | iPhone, iPod |
| Age rating | 17+ | 17+ |
| Developer | [Caerus Marketing Group LLC](https://appshunter.io/developer/1301549334) | [Reply MD](https://appshunter.io/developer/1794507768) |

## What reviewers say

### INFORMUS

[App page](https://appshunter.io/ios/app/informus/id6471454872)

This app helps clinical trial participants manage their study information, including treatment plans, appointments, and payments. It allows users to track daily dosage results and access helpful study resources through a user-friendly interface.

**Highlights:** Access treatment plans and appointments, View payment information, Track daily dosage results, Access study information, User-friendly interface

**Features:** macOS Compatibility

**In-app purchases:** none


### ReplyMD

[App page](https://appshunter.io/ios/app/replymd/id6741511114)

Connect with verified healthcare professionals and join peer-to-peer communities for reliable health information and support. Ask questions, share experiences, and access curated articles to manage your health journey.

**Highlights:** Verified healthcare professionals, Peer-to-peer communities, Meaningful discussions, Curated articles and resources, Connect with others, Share knowledge

**Features:** macOS Compatibility

**In-app purchases:** none


## Frequently asked questions

### Is INFORMUS free?

INFORMUS is free to download, with no in-app purchases.

### Is ReplyMD free?

ReplyMD is free to download, with no in-app purchases.

### Which has better reviews, INFORMUS or ReplyMD?

ReplyMD is rated higher. INFORMUS averages 4.3 out of 5 from 8 ratings, while ReplyMD averages 5.0 from 4 ratings.

### Do INFORMUS or ReplyMD have ads?

Neither INFORMUS nor ReplyMD shows ads.

### Which is updated more often, INFORMUS or ReplyMD?

INFORMUS ships an update monthly, and ReplyMD every 10 days. Most recently, INFORMUS was updated on October 7, 2026 and ReplyMD on October 5, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*