# Bio vs Annotare

The clearest difference is in-app purchases: Annotare at none against Bio's 3. On price, update cadence, ads and device support there is nothing between them.

Both are free to download. Bio sells 3 in-app purchases, starting at $2.99 per month. Annotare asks for nothing beyond the download.

Bio ships an update every 2 weeks, Annotare fortnightly. The most recent releases landed on September 30, 2026 and October 7, 2026 respectively.

## The numbers

| Metric | Bio | Annotare |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[5.0 (2 ratings)](https://appshunter.io/ios/app/bio-calculator/id6498629520/reviews)** | — |
| Number of ratings | **2** | — |
| In-app purchases | Yes | **No** |
| Ads | No | No |
| Update frequency | **Every 2 weeks** | Fortnightly |
| Monetization | Freemium | — |
| Size | 51 MB | 13 MB |
| Requires iOS | **17.0** | 18.5 |
| Devices | iPhone, iPad | iPhone, iPad |
| Age rating | 4+ | 4+ |
| Developer | [杰 吴](https://appshunter.io/developer/1729187814) | [Barthelemy Charrier](https://appshunter.io/developer/1824739707) |

## What reviewers say

### Bio

[App page](https://appshunter.io/ios/app/bio-calculator/id6498629520)

This scientific assistant provides researchers and students with essential tools for everyday lab calculations. It offers modules for protein and nucleic acid conversions, solution preparation, microbiology, and buffer recipes. Streamline your laboratory workflow with precise and efficient scientific computations.

**Highlights:** Protein & Peptide Conversion, Nucleic Acid & Genomics Toolkit, Biochemistry & Solution Preparation, Microbiology & Cell Culture Tools, Buffer & Solution Preparation Library, Native iOS Performance

**Features:** macOS Compatibility

**In-app purchases (3)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Monthly Plan | $2.99 | per month |
| Yearly Plan | $19.99 | per year |
| Lifetime member | $44.99 | one-time |


### Annotare

[App page](https://appshunter.io/ios/app/annotare/id6748240456)

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


## Frequently asked questions

### Is Bio free?

Bio is free to download, with in-app purchases available.

### Is Annotare free?

Annotare is free to download, with no in-app purchases.

### Do Bio or Annotare have ads?

Neither Bio nor Annotare shows ads.

### Which is updated more often, Bio or Annotare?

Bio ships an update every 2 weeks, and Annotare fortnightly. Most recently, Bio was updated on September 30, 2026 and Annotare on October 7, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*