# STI Tx Guide vs Guideline Central

The clearest difference is review sentiment: Guideline Central at 100% against STI Tx Guide's 36%. Guideline Central also leads on rating (5.0 vs 3.5) and update cadence (every 2 weeks vs every 2 months). STI Tx Guide's advantage is ratings volume (36 vs 2). On price, ads, in-app purchases and monetization model there is nothing between them.

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

Guideline Central holds the better App Store score, 5.0 against 3.5. That said, the two scores are not equally well evidenced: STI Tx Guide has 36 ratings behind it against 2, so its average is the more settled of the two. Written reviews point the same way: 36% of STI Tx Guide's written reviews are positive against 100% of Guideline Central's.

STI Tx Guide ships an update every 2 months, Guideline Central every 2 weeks. The most recent releases landed on October 8, 2026 and October 16, 2026 respectively.

## The numbers

| Metric | STI Tx Guide | Guideline Central |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [3.5 (36 ratings)](https://appshunter.io/ios/app/sti-tx-guide/id655206856/reviews) | **[5.0 (2 ratings)](https://appshunter.io/ios/app/guideline-central/id6770587739/reviews)** |
| Number of ratings | **36** | 2 |
| Positive reviews | 35.7% of reviews | **100.0% of reviews** |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | Every 2 months | **Every 2 weeks** |
| Monetization | Free | Free |
| Size | 36 MB | 36 MB |
| Requires iOS | **15.0** | 15.1 |
| Devices | iPhone, iPod | **iPhone, iPad, iPod** |
| Age rating | 12+ | 17+ |
| Developer | [Centers For Disease Control and Prevention](https://appshunter.io/developer/439259253) | [International Guidelines Center, Inc](https://appshunter.io/developer/451486344) |

## What reviewers say

### STI Tx Guide

[App page](https://appshunter.io/ios/app/sti-tx-guide/id655206856)

Provides healthcare professionals with up-to-date, evidence-based recommendations for the prevention, diagnosis, and treatment of sexually transmitted infections. Features include clinical care guidance, sexual history resources, and patient materials for effective patient management.

**Highlights:** STI prevention recommendations, Diagnosis guidance, Treatment protocols, Clinical care assistance, Sexual history resources, Patient management tools

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


### Guideline Central

[App page](https://appshunter.io/ios/app/guideline-central/id6770587739)

Access a vast collection of clinical practice guidelines and decision-support tools. Quickly find recommendations, calculators, drug information, and more to improve patient care. Stay updated with the latest medical research and guidelines from global associations.

**Highlights:** Clinical practice guideline repository, Guideline summaries and full text links, Clinical calculators, Drug monographs, Clinical trials search, Preventive services recommendations, PubMed search integration

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


## Frequently asked questions

### Is STI Tx Guide free?

STI Tx Guide is free to download, with no in-app purchases.

### Is Guideline Central free?

Guideline Central is free to download, with no in-app purchases.

### Which has better reviews, STI Tx Guide or Guideline Central?

Guideline Central is rated higher. STI Tx Guide averages 3.5 out of 5 from 36 ratings, while Guideline Central averages 5.0 from 2 ratings.

### Do STI Tx Guide or Guideline Central have ads?

Neither STI Tx Guide nor Guideline Central shows ads.

### Which is updated more often, STI Tx Guide or Guideline Central?

STI Tx Guide ships an update every 2 months, and Guideline Central every 2 weeks. Most recently, STI Tx Guide was updated on October 8, 2026 and Guideline Central on October 16, 2026.

---

*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*