# ACP MKSAP vs Guideline Central

The clearest difference is review sentiment: Guideline Central at 100% against ACP MKSAP's 57%. Guideline Central also leads on rating (5.0 vs 4.2) and in-app purchases (none vs 1). ACP MKSAP's advantage is ratings volume (16 vs 2) and iOS requirement (13.0 vs 15.1). On price, update cadence, ads and device support there is nothing between them.

Both are free to download. ACP MKSAP sells 1 in-app purchase, starting at $999.99 per year. Guideline Central asks for nothing beyond the download.

Guideline Central holds the better App Store score, 5.0 against 4.2. That said, the two scores are not equally well evidenced: ACP MKSAP has 16 ratings behind it against 2, so its average is the more settled of the two. Written reviews point the same way: 57% of ACP MKSAP's written reviews are positive against 100% of Guideline Central's.

ACP MKSAP ships an update every 10 days, Guideline Central every 2 weeks. The most recent releases landed on October 21, 2026 and October 24, 2026 respectively.

## The numbers

| Metric | ACP MKSAP | Guideline Central |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [4.2 (16 ratings)](https://appshunter.io/ios/app/acp-mksap/id6739636797/reviews) | **[5.0 (2 ratings)](https://appshunter.io/ios/app/guideline-central/id6770587739/reviews)** |
| Number of ratings | **16** | 2 |
| Positive reviews | 57.1% of reviews | **100.0% of reviews** |
| In-app purchases | Yes | **No** |
| Ads | No | No |
| Update frequency | **Every 10 days** | Every 2 weeks |
| Monetization | Free with in-app purchases | **Free** |
| Size | 540 MB | 36 MB |
| Requires iOS | **13.0** | 15.1 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [American College of Physicians](https://appshunter.io/developer/371090673) | [International Guidelines Center, Inc](https://appshunter.io/developer/451486344) |

## What reviewers say

### ACP MKSAP

[App page](https://appshunter.io/ios/app/acp-mksap/id6739636797)

Access comprehensive internal medicine knowledge and practice exam-style questions offline. This app syncs your progress with the online version when connected to the internet. It's designed for physicians to stay updated on the latest evidence and enhance their clinical decision-making skills.

**Highlights:** Offline access to text and questions, Thousands of exam-like multiple-choice questions, Patient-based clinical scenarios, Syncs progress with online version, Includes figures, charts, and tables, Targets knowledge gaps

**Features:** Vision Pro support

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Non-member in-app price | $999.99 | per year |


### Guideline Central

[App page](https://appshunter.io/ios/app/guideline-central/id6770587739)

Access a vast collection of clinical practice guidelines and decision-support tools. Quickly find recommendations, calculators, drug information, and more to improve patient care. Stay updated with the latest medical research and guidelines from global associations.

**Highlights:** Clinical practice guideline repository, Guideline summaries and full text links, Clinical calculators, Drug monographs, Clinical trials search, Preventive services recommendations, PubMed search integration

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


## Frequently asked questions

### Is ACP MKSAP free?

ACP MKSAP is free to download, with in-app purchases available.

### Is Guideline Central free?

Guideline Central is free to download, with no in-app purchases.

### Which has better reviews, ACP MKSAP or Guideline Central?

Guideline Central is rated higher. ACP MKSAP averages 4.2 out of 5 from 16 ratings, while Guideline Central averages 5.0 from 2 ratings.

### Do ACP MKSAP or Guideline Central have ads?

Neither ACP MKSAP nor Guideline Central shows ads.

### Which is updated more often, ACP MKSAP or Guideline Central?

ACP MKSAP ships an update every 10 days, and Guideline Central every 2 weeks. Most recently, ACP MKSAP was updated on October 21, 2026 and Guideline Central on October 24, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*