# EBMRef vs Synapse for Safari

The clearest difference is update cadence: Synapse for Safari at every 2 days against EBMRef's every 3 weeks. Synapse for Safari also leads on device support (4 vs 2) and iOS requirement (15.0 vs 26.0). On price, ads and in-app purchases there is nothing between them.

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

EBMRef ships an update every 3 weeks, Synapse for Safari every 2 days. The most recent releases landed on September 23, 2026 and October 17, 2026 respectively.

## The numbers

| Metric | EBMRef | Synapse for Safari |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[5.0 (21 ratings)](https://appshunter.io/ios/app/ebmref/id6751447390/reviews)** | — |
| Number of ratings | **21** | — |
| Positive reviews | 100.0% of reviews | — |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | Every 3 weeks | **Every 2 days** |
| Monetization | Free | — |
| Size | 8 MB | 2 MB |
| Requires iOS | 26.0 | **15.0** |
| Devices | iPhone, iPad | **iPhone, iPad, iPod, Mac** |
| Age rating | 17+ | 17+ |
| Developer | [Rishi Kumar](https://appshunter.io/developer/1434016052) | [Synapse Social LLC](https://appshunter.io/developer/1769426157) |

## What reviewers say

### EBMRef

[App page](https://appshunter.io/ios/app/ebmref/id6751447390)

Access summaries of landmark medical research across specialties. Quickly find key trial details like interventions, outcomes, and clinical relevance for bedside reference. Intended for educational use, it's a supplement to, not a replacement for, professional medical advice.

**Highlights:** Landmark research summaries, Organized by medical specialty, Key trial details (name, year, interventions, outcomes), Clinical relevance distilled, Quick bedside access, Educational and informational

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


### Synapse for Safari

[App page](https://appshunter.io/ios/app/synapse-for-safari/id6761625356)

**Features:** Safari Extension, Vision Pro support

**In-app purchases:** none


## Frequently asked questions

### Is EBMRef free?

EBMRef is free to download, with no in-app purchases.

### Is Synapse for Safari free?

Synapse for Safari is free to download, with no in-app purchases.

### Do EBMRef or Synapse for Safari have ads?

Neither EBMRef nor Synapse for Safari shows ads.

### Which is updated more often, EBMRef or Synapse for Safari?

EBMRef ships an update every 3 weeks, and Synapse for Safari every 2 days. Most recently, EBMRef was updated on September 23, 2026 and Synapse for Safari on October 17, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*