# DE.med vs Guideline Central

The clearest difference is in-app purchases: Guideline Central at none against DE.med's 3. On price, update cadence, ads and device support there is nothing between them.

Both are free to download. DE.med sells 3 in-app purchases, starting at $8.99 per month. Guideline Central asks for nothing beyond the download.

DE.med ships an update monthly, Guideline Central every 2 weeks. The most recent releases landed on September 17, 2026 and September 30, 2026 respectively.

## The numbers

| Metric | DE.med | Guideline Central |
| --- | --- | --- |
| Price | Free | Free |
| Rating | — | **[5.0 (2 ratings)](https://appshunter.io/ios/app/guideline-central/id6770587739/reviews)** |
| Number of ratings | — | **2** |
| Positive reviews | — | 100.0% of reviews |
| In-app purchases | Yes | **No** |
| Ads | No | No |
| Update frequency | Monthly | **Every 2 weeks** |
| Monetization | — | Free |
| Size | 98 MB | 36 MB |
| Requires iOS | 16.4 | **15.1** |
| Devices | iPhone, iPad | **iPhone, iPad, iPod** |
| Age rating | 17+ | 17+ |
| Developer | [Gustavo cesar Sola Barreto Marcelino](https://appshunter.io/developer/1875104005) | [International Guidelines Center, Inc](https://appshunter.io/developer/451486344) |

## What reviewers say

### DE.med

[App page](https://appshunter.io/ios/app/demed/id6758807897)

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (3)**

| Purchase | Price | Billing |
| --- | --- | --- |
| DE.med Pro Monthly | $8.99 | per month |
| DE.med Pro Annual | $89.99 | per year |
| DE.med Pro Lifetime | $99.99 | one-time |


### Guideline Central

[App page](https://appshunter.io/ios/app/guideline-central/id6770587739)

Access a vast collection of clinical practice guidelines and decision-support tools. Quickly find recommendations, calculators, drug information, and more to improve patient care. Stay updated with the latest medical research and guidelines from global associations.

**Highlights:** Clinical practice guideline repository, Guideline summaries and full text links, Clinical calculators, Drug monographs, Clinical trials search, Preventive services recommendations, PubMed search integration

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


## Frequently asked questions

### Is DE.med free?

DE.med is free to download, with in-app purchases available.

### Is Guideline Central free?

Guideline Central is free to download, with no in-app purchases.

### Do DE.med or Guideline Central have ads?

Neither DE.med nor Guideline Central shows ads.

### Which is updated more often, DE.med or Guideline Central?

DE.med ships an update monthly, and Guideline Central every 2 weeks. Most recently, DE.med was updated on September 17, 2026 and Guideline Central on September 30, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*