# Milligram vs Substrato

The clearest difference is update cadence: Milligram at every 4 days against Substrato's every 2 weeks. On price, ads, in-app purchases and device support there is nothing between them.

Both are free to download. Milligram sells 3 in-app purchases, starting at $17.49 per month and Substrato sells 5 in-app purchases, starting at $4.99 per month. Whichever you choose, the download price is not the number that matters.

Milligram ships an update every 4 days, Substrato every 2 weeks. The most recent releases landed on October 12, 2026 and October 5, 2026 respectively.

## The numbers

| Metric | Milligram | Substrato |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[4.7 (313 ratings)](https://appshunter.io/ios/app/milligram-peptide-tracker/id6759593151/reviews)** | — |
| Number of ratings | **313** | — |
| Positive reviews | 68.6% of reviews | — |
| In-app purchases | Yes | Yes |
| Ads | No | No |
| Update frequency | **Every 4 days** | Every 2 weeks |
| Monetization | Free with in-app purchases | — |
| Size | 169 MB | 16 MB |
| Requires iOS | **17.0** | 17.6 |
| Devices | **iPhone, Apple Watch** | iPhone |
| Age rating | 12+ | 4+ |
| Developer | [Enzo Anderson](https://appshunter.io/developer/1879259083) | [Cristian Garske](https://appshunter.io/developer/1523712925) |

## What reviewers say

### Milligram

[App page](https://appshunter.io/ios/app/milligram-peptide-tracker/id6759593151)

Optimize your health and performance with science-backed data. Track peptide levels, analyze bloodwork, and monitor progress with intelligent insights. Get personalized feedback on your protocol and health metrics.

**Highlights:** Intelligent protocol analysis, Compound level tracking, Bloodwork analysis and biomarker flagging, Comprehensive compound library, Progress scans for body composition, Stack analytics and interaction flagging, Journaling for health metrics, Reconstitution calculator

**Features:** macOS Compatibility, Apple Watch app, Vision Pro support

**In-app purchases (3)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Milligram Pro | $17.49 | per month |
| Milligram Pro | $49.99 | per year |
| Milligram Pro | $69.99 | per year |


### Substrato

[App page](https://appshunter.io/ios/app/substrato-macro-protocol/id6763404287)

**Features:** Vision Pro support

**In-app purchases (5)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Premium | $4.99 | per month |
| Trainer | $14.99 | per month |
| Premium | $39.99 | per year |
| Trainer | $119.99 | per year |
| Premium Lifetime | $79.99 | one-time |


## Frequently asked questions

### Is Milligram free?

Milligram is free to download, with in-app purchases available.

### Is Substrato free?

Substrato is free to download, with in-app purchases available.

### Do Milligram or Substrato have ads?

Neither Milligram nor Substrato shows ads.

### Which is updated more often, Milligram or Substrato?

Milligram ships an update every 4 days, and Substrato every 2 weeks. Most recently, Milligram was updated on October 12, 2026 and Substrato on October 5, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*