# NCCN Guidelines® vs CTCAE 5 Pro

The clearest difference is rating: CTCAE 5 Pro at 4.8 against NCCN Guidelines®'s 3.6. NCCN Guidelines®'s advantage is in-app purchases (none vs 2) and review sentiment (13% vs 0%). On price, ratings volume, update cadence and ads there is nothing between them.

Both are free to download. CTCAE 5 Pro sells 2 in-app purchases, starting at $1.99 per month. NCCN Guidelines® asks for nothing beyond the download.

CTCAE 5 Pro holds the better App Store score, 4.8 against 3.6. Both are backed by a comparable volume of ratings — 24 and 38 respectively. Written reviews complicate that: 13% of NCCN Guidelines®'s written reviews are positive against 0% of CTCAE 5 Pro's, so the app with the better star average is not the one people write more warmly about.

NCCN Guidelines® ships an update every 2 months, CTCAE 5 Pro every 5 weeks. The most recent releases landed on August 26, 2026 and September 22, 2026 respectively.

## The numbers

| Metric | NCCN Guidelines® | CTCAE 5 Pro |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [3.6 (24 ratings)](https://appshunter.io/ios/app/nccn-guidelines/id775500217/reviews) | **[4.8 (38 ratings)](https://appshunter.io/ios/app/ctcae-5-pro/id1625569535/reviews)** |
| Number of ratings | 24 | **38** |
| Positive reviews | **12.5% of reviews** | 0.0% of reviews |
| In-app purchases | **No** | Yes |
| Ads | No | No |
| Update frequency | Every 2 months | **Every 5 weeks** |
| Monetization | **Free** | Freemium |
| Size | 118 MB | 60 MB |
| Requires iOS | **13.1** | 15.5 |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [National Comprehensive Cancer Network®](https://appshunter.io/developer/1168594705) | [Koichiro Watanabe](https://appshunter.io/developer/1077985400) |

## What reviewers say

### NCCN Guidelines®

[App page](https://appshunter.io/ios/app/nccn-guidelines/id775500217)

This app provides healthcare professionals with convenient access to comprehensive clinical practice guidelines for oncology. It aims to improve the quality and effectiveness of cancer care by offering evidence-based recommendations for diagnosis, treatment, and supportive services.

**Highlights:** Virtual Library of NCCN Guidelines, Oncology clinical practice guidelines, Evidence-based recommendations, Supports cancer care decision-making, Covers 97% of US cancer cases

**Features:** Vision Pro support

**In-app purchases:** none


### CTCAE 5 Pro

[App page](https://appshunter.io/ios/app/ctcae-5-pro/id1625569535)

This app helps review and take notes on CTCAE documents. It offers local data storage for privacy and premium features like version comparison and advanced note-taking with a subscription.

**Highlights:** Streamlined CTCAE Document Access, Local data storage for enhanced privacy, Version comparison tool, Advanced chronological note-taking with hashtags, Custom app creation from spreadsheets, Flexible backup and archiving (XLSX, CSV)

**Features:** macOS Compatibility, Family Sharing, Vision Pro support

**In-app purchases (2)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Monthly subscription | $1.99 | per month |
| Annual subscription | $9.99 | per year |


## Frequently asked questions

### Is NCCN Guidelines® free?

NCCN Guidelines® is free to download, with no in-app purchases.

### Is CTCAE 5 Pro free?

CTCAE 5 Pro is free to download, with in-app purchases available.

### Which has better reviews, NCCN Guidelines® or CTCAE 5 Pro?

CTCAE 5 Pro is rated higher. NCCN Guidelines® averages 3.6 out of 5 from 24 ratings, while CTCAE 5 Pro averages 4.8 from 38 ratings.

### Do NCCN Guidelines® or CTCAE 5 Pro have ads?

Neither NCCN Guidelines® nor CTCAE 5 Pro shows ads.

### Which is updated more often, NCCN Guidelines® or CTCAE 5 Pro?

NCCN Guidelines® ships an update every 2 months, and CTCAE 5 Pro every 5 weeks. Most recently, NCCN Guidelines® was updated on August 26, 2026 and CTCAE 5 Pro on September 22, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*